Spermidine Suppresses Age-Associated Memory Impairment by Preventing Adverse Increase of Presynaptic Active Zone Size and Release

KIF1A/UNC-104 Transports ATG-9 to Regulate Neurodevelopment and Autophagy at Synapses

(2016) Andrea K.H. Stavoe et al.   DEVELOPMENTAL CELL

Maturation of active zone assembly byDrosophilaBruchpilot

(2016) Wernher Fouquet et al.   JOURNAL OF CELL BIOLOGY

Long-distance autophagy

(2015) Aileen R Ariosa et al.   Autophagy

Olfactory learning skews mushroom body output pathways to steer behavioral choice in Drosophila

(2015) David Owald et al.   CURRENT OPINION IN NEUROBIOLOGY

Aging Impairs Protein-Synthesis-Dependent Long-Term Memory in Drosophila

(2015) A. Tonoki et al.   JOURNAL OF NEUROSCIENCE

Activity of Defined Mushroom Body Output Neurons Underlies Learned Olfactory Behavior in Drosophila

(2015) David Owald et al.   NEURON

Hsc70-4 Deforms Membranes to Promote Synaptic Protein Turnover by Endosomal Microautophagy

(2015) Valerie Uytterhoeven et al.   NEURON

Heterosynaptic Plasticity Underlies Aversive Olfactory Learning in Drosophila

(2015) Toshihide Hige et al.   NEURON

Presynaptic spinophilin tunes neurexin signalling to control active zone architecture and function

(2015) Karzan Muhammad et al.   Nature Communications

Optical Dissection of Experience-Dependent Pre- and Postsynaptic Plasticity in the Drosophila Brain

(2015) Ulrike Pech et al.   Cell Reports

Metabolic Control of Autophagy

(2014) Lorenzo Galluzzi et al.   CELL

The Search for Antiaging Interventions: From Elixirs to Fasting Regimens

(2014) Rafael de Cabo et al.   CELL

Spermidine protects against α-synuclein neurotoxicity

(2014) Sabrina Büttner et al.   CELL CYCLE

Spermidine induces autophagy by inhibiting the acetyltransferase EP300

(2014) F Pietrocola et al.   CELL DEATH AND DIFFERENTIATION

Evoked and Spontaneous Transmission Favored by Distinct Sets of Synapses

(2014) Einat S. Peled et al.   CURRENT BIOLOGY

Autophagosome Biogenesis in Primary Neurons Follows an Ordered and Spatially Regulated Pathway

(2014) Sandra Maday et al.   DEVELOPMENTAL CELL

An Age-Dependent Change in the Set Point of Synaptic Homeostasis

(2014) R. E. Mahoney et al.   JOURNAL OF NEUROSCIENCE

Sparse, decorrelated odor coding in the mushroom body enhances learned odor discrimination

(2014) Andrew C Lin et al.   NATURE NEUROSCIENCE

Sleep and the Price of Plasticity: From Synaptic and Cellular Homeostasis to Memory Consolidation and Integration

(2014) Giulio Tononi et al.   NEURON

Quantitative super-resolution imaging of Bruchpilot distinguishes active zone states

(2014) Nadine Ehmann et al.   Nature Communications

HDAC6 Is a Bruchpilot Deacetylase that Facilitates Neurotransmitter Release

(2014) Katarzyna Miskiewicz et al.   Cell Reports

Drep-2 is a novel synaptic protein important for learning and memory

(2014) Till F M Andlauer et al.   eLife

Spermidine-triggered autophagy ameliorates memory during aging

(2013) Stephan J Sigrist et al.   Autophagy

Functional Aging in the Nervous System Contributes to Age-Dependent Motor Activity Decline in C. elegans

(2013) Jie Liu et al.   Cell Metabolism

The Bruchpilot cytomatrix determines the size of the readily releasable pool of synaptic vesicles

(2013) Tanja Matkovic et al.   JOURNAL OF CELL BIOLOGY

Spontaneous and Evoked Release Are Independently Regulated at Individual Active Zones

(2013) J. E. Melom et al.   JOURNAL OF NEUROSCIENCE

Rapid Combinatorial ERLIC–SCX Solid-Phase Extraction for In-Depth Phosphoproteome Analysis

(2013) Mostafa Zarei et al.   JOURNAL OF PROTEOME RESEARCH

Restoring polyamines protects from age-induced memory impairment in an autophagy-dependent manner

(2013) Varun K Gupta et al.   NATURE NEUROSCIENCE

Homeostatic Signaling and the Stabilization of Neural Function

(2013) Graeme W. Davis   NEURON

Neurotransmitter Release: The Last Millisecond in the Life of a Synaptic Vesicle

(2013) Thomas C. Südhof   NEURON

The synaptic vesicle SNARE neuronal Synaptobrevin promotes endolysosomal degradation and prevents neurodegeneration

(2012) Adam Haberman et al.   JOURNAL OF CELL BIOLOGY

Different classes of input and output neurons reveal new features in microglomeruli of the adult Drosophila mushroom body calyx

(2012) Nancy J. Butcher et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Cooperation of Syd-1 with Neurexin synchronizes pre- with postsynaptic assembly

(2012) David Owald et al.   NATURE NEUROSCIENCE

Structural plasticity upon learning: regulation and functions

(2012) Pico Caroni et al.   NATURE REVIEWS NEUROSCIENCE

The Presynaptic Active Zone

(2012) Thomas C. Südhof   NEURON

TrakEM2 Software for Neural Circuit Reconstruction

(2012) Albert Cardona et al.   PLoS One

Aging impairs intermediate-term behavioral memory by disrupting the dorsal paired medial neuron memory trace

(2012) A. Tonoki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Spermidine and resveratrol induce autophagy by distinct pathways converging on the acetylproteome

(2011) Eugenia Morselli et al.   JOURNAL OF CELL BIOLOGY

Bruchpilot, A Synaptic Active Zone Protein for Anesthesia-Resistant Memory

(2011) S. Knapek et al.   JOURNAL OF NEUROSCIENCE

Optical quantal analysis of synaptic transmission in wild-type and rab3-mutant Drosophila motor axons

(2011) Einat S Peled et al.   NATURE NEUROSCIENCE

Protein scaffolds in the coupling of synaptic exocytosis and endocytosis

(2011) Volker Haucke et al.   NATURE REVIEWS NEUROSCIENCE

ELP3 Controls Active Zone Morphology by Acetylating the ELKS Family Member Bruchpilot

(2011) Katarzyna Miśkiewicz et al.   NEURON

RIM-Binding Protein, a Central Part of the Active Zone, Is Essential for Neurotransmitter Release

(2011) K. S. Y. Liu et al.   SCIENCE

How synapsin I may cluster synaptic vesicles

(2011) Oleg Shupliakov et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Spermidine: A novel autophagy inducer and longevity elixir

(2010) Frank Madeo et al.   Autophagy

Structural Long-Term Changes at Mushroom Body Input Synapses

(2010) Malte C. Kremer et al.   CURRENT BIOLOGY

Structural and functional plasticity of the cytoplasmic active zone

(2010) Stephan J Sigrist et al.   CURRENT OPINION IN NEUROBIOLOGY

Acute Inhibition of PKA Activity at Old Ages Ameliorates Age-Related Memory Impairment in Drosophila

(2010) D. Yamazaki et al.   JOURNAL OF NEUROSCIENCE

Senescent synapses and hippocampal circuit dynamics

(2010) Sara N. Burke et al.   TRENDS IN NEUROSCIENCES

Dopamine reveals neural circuit mechanisms of fly memory

(2010) Scott Waddell   TRENDS IN NEUROSCIENCES

Induction of autophagy by spermidine promotes longevity

(2009) Tobias Eisenberg et al.   NATURE CELL BIOLOGY

Imaging neural activity in worms, flies and mice with improved GCaMP calcium indicators

(2009) Lin Tian et al.   NATURE METHODS

Widespread Changes in Synaptic Markers as a Function of Sleep and Wakefulness in Drosophila

(2009) Giorgio F. Gilestro et al.   SCIENCE

The Self-Tuning Neuron: Synaptic Scaling of Excitatory Synapses

(2008) Gina G. Turrigiano   CELL

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY