Notch stimulates growth by direct regulation of genes involved in the control of glycolysis and the tricarboxylic acid cycle

ECM1 promotes the Warburg effect through EGF-mediated activation of PKM2

(2015) Kyung-min Lee et al.   CELLULAR SIGNALLING

Extracellular Adenosine Mediates a Systemic Metabolic Switch during Immune Response

(2015) Adam Bajgar et al.   PLOS BIOLOGY

From Fly Wings to Targeted Cancer Therapies: A Centennial for Notch Signaling

(2014) Panagiotis Ntziachristos et al.   CANCER CELL

Long non-coding RNA UCA1 promotes glycolysis by upregulating hexokinase 2 through the mTOR-STAT3/microRNA143 pathway

(2014) Zhengkun Li et al.   CANCER SCIENCE

Alteration of Mitochondrial Proteome Due to Activation of Notch1 Signaling Pathway

(2014) Nandini Pal Basak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Notch controls the survival of memory CD4+ T cells by regulating glucose uptake

(2014) Yoichi Maekawa et al.   NATURE MEDICINE

Coordinated Metabolic Transitions During Drosophila Embryogenesis and the Onset of Aerobic Glycolysis

(2014) Jason M. Tennessen et al.   G3-Genes Genomes Genetics

Role of PFKFB3-Driven Glycolysis in Vessel Sprouting

(2013) Katrien De Bock et al.   CELL

Regulation of Glycolysis by Pdk Functions as a Metabolic Checkpoint for Cell Cycle Quiescence in Hematopoietic Stem Cells

(2013) Keiyo Takubo et al.   Cell Stem Cell

Oxygen-independent Regulation of HIF-1: Novel Involvement of PI3K/ AKT/mTOR Pathway in Cancer

(2013) Faton Agani et al.   CURRENT CANCER DRUG TARGETS

Stem cells living with a Notch

(2013) U. Koch et al.   DEVELOPMENT

Nutrient-sensing pathways and metabolic regulation in stem cells

(2013) Joshua D. Ochocki et al.   JOURNAL OF CELL BIOLOGY

Signal integration by mTORC1 coordinates nutrient input with biosynthetic output

(2013) Christian C. Dibble et al.   NATURE CELL BIOLOGY

Targeting cellular metabolism to improve cancer therapeutics

(2013) Y Zhao et al.   Cell Death & Disease

Metabolic sensors and their interplay with cell signalling and transcription

(2012) Alena Krejčí   BIOCHEMICAL SOCIETY TRANSACTIONS

Metabolic Reprogramming: A Cancer Hallmark Even Warburg Did Not Anticipate

(2012) Patrick S. Ward et al.   CANCER CELL

Dissecting the mechanisms of Notch induced hyperplasia

(2012) Alexandre Djiane et al.   EMBO JOURNAL

HIF1α induced switch from bivalent to exclusively glycolytic metabolism during ESC-to-EpiSC/hESC transition

(2012) Wenyu Zhou et al.   EMBO JOURNAL

The Drosophila Estrogen-Related Receptor Directs a Metabolic Switch that Supports Developmental Growth

(2011) Jason M. Tennessen et al.   Cell Metabolism

Cutting Edge: Distinct Glycolytic and Lipid Oxidative Metabolic Programs Are Essential for Effector and Regulatory CD4+ T Cell Subsets

(2011) R. D. Michalek et al.   JOURNAL OF IMMUNOLOGY

Hypo- and hyperactivated Notch signaling induce a glycolytic switch through distinct mechanisms

(2011) S. K.- J. Landor et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-wide analysis reveals conserved and divergent features of Notch1/RBPJ binding in human and murine T-lymphoblastic leukemia cells

(2011) H. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interaction Between Notch and Hif-  in Development and Survival of Drosophila Blood Cells

(2011) T. Mukherjee et al.   SCIENCE

Specificity of Notch pathway activation: Twist controls the transcriptional output in adult muscle progenitors

(2010) F. Bernard et al.   DEVELOPMENT

A Combined Ex Vivo and In Vivo RNAi Screen for Notch Regulators in Drosophila Reveals an Extensive Notch Interaction Network

(2010) Abil Saj et al.   DEVELOPMENTAL CELL

Notch1-induced mammary tumor development is cyclin D1-dependent and correlates with expansion of pre-malignant multipotent duct-limited progenitors

(2010) H Ling et al.   ONCOGENE

Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

(2009) Lenny Dang et al.   NATURE

Direct Response to Notch Activation: Signaling Crosstalk and Incoherent Logic

(2009) A. Krejci et al.   Science Signaling

Effective Quenching Processes for Physiologically Valid Metabolite Profiling of Suspension Cultured Mammalian Cells

(2008) Christopher A. Sellick et al.   ANALYTICAL CHEMISTRY

Notch signaling mediates G1/S cell-cycle progression in T cells via cyclin D3 and its dependent kinases

(2008) I. Joshi et al.   BLOOD

Interaction with factor inhibiting HIF-1 defines an additional mode of cross-coupling between the Notch and hypoxia signaling pathways

(2008) X. Zheng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanisms Underlying Hypoxia Tolerance in Drosophila melanogaster: hairy as a Metabolic Switch

(2008) Dan Zhou et al.   PLoS Genetics