Implementation of next generation sequencing into pediatric hematology-oncology practice: moving beyond actionable alterations
出版年份 2016 全文链接
标题
Implementation of next generation sequencing into pediatric hematology-oncology practice: moving beyond actionable alterations
作者
关键词
Whole exome sequencing, RNA sequencing, Precision medicine, Pediatric oncology
出版物
Genome Medicine
Volume 8, Issue 1, Pages -
出版商
Springer Nature
发表日期
2016-12-19
DOI
10.1186/s13073-016-0389-6
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia
- (2016) D. A. Arber et al. BLOOD
- MultiDimensional ClinOmics for Precision Therapy of Children and Adolescent Young Adults with Relapsed and Refractory Cancer: A Report from the Center for Cancer Research
- (2016) W. Chang et al. CLINICAL CANCER RESEARCH
- The Spectrum of Clinical Utilities in Molecular Pathology Testing Procedures for Inherited Conditions and Cancer
- (2016) Loren Joseph et al. JOURNAL OF MOLECULAR DIAGNOSTICS
- Integrating Genomics Into Clinical Pediatric Oncology Using the Molecular Tumor Board at the Memorial Sloan Kettering Cancer Center
- (2016) Michael V. Ortiz et al. PEDIATRIC BLOOD & CANCER
- Development and clinical application of an integrative genomic approach to personalized cancer therapy
- (2016) Andrew V. Uzilov et al. Genome Medicine
- Diagnostic Yield of Clinical Tumor and Germline Whole-Exome Sequencing for Children With Solid Tumors
- (2016) D. Williams Parsons et al. JAMA Oncology
- Multicenter Feasibility Study of Tumor Molecular Profiling to Inform Therapeutic Decisions in Advanced Pediatric Solid Tumors
- (2016) Marian H. Harris et al. JAMA Oncology
- A targeted next-generation sequencing method for identifying clinically relevant mutation profiles in lung adenocarcinoma
- (2016) Di Shao et al. Scientific Reports
- Advances in the translational genomics of neuroblastoma: From improving risk stratification and revealing novel biology to identifying actionable genomic alterations
- (2015) Kristopher R. Bosse et al. CANCER
- Molecular Classification of Ependymal Tumors across All CNS Compartments, Histopathological Grades, and Age Groups
- (2015) Kristian W. Pajtler et al. CANCER CELL
- Phenotypic and genotypic characterisation of biallelic mismatch repair deficiency (BMMR-D) syndrome
- (2015) Carol A. Durno et al. EUROPEAN JOURNAL OF CANCER
- Integrative Clinical Sequencing in the Management of Refractory or Relapsed Cancer in Youth
- (2015) Rajen J. Mody et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Feasibility of Large-Scale Genomic Testing to Facilitate Enrollment Onto Genomically Matched Clinical Trials
- (2015) Funda Meric-Bernstam et al. JOURNAL OF CLINICAL ONCOLOGY
- Advances in Risk Classification and Treatment Strategies for Neuroblastoma
- (2015) Navin R. Pinto et al. JOURNAL OF CLINICAL ONCOLOGY
- Molecular subgroups of atypical teratoid rhabdoid tumours in children: an integrated genomic and clinicopathological analysis
- (2015) Jonathon Torchia et al. LANCET ONCOLOGY
- Acute Lymphoblastic Leukemia in Children
- (2015) Stephen P. Hunger et al. NEW ENGLAND JOURNAL OF MEDICINE
- Germline Mutations in Predisposition Genes in Pediatric Cancer
- (2015) Jinghui Zhang et al. NEW ENGLAND JOURNAL OF MEDICINE
- Activating mutations of STAT5B and STAT3 in lymphomas derived from γδ-T or NK cells
- (2015) Can Küçük et al. Nature Communications
- Development and Validation of a Scalable Next-Generation Sequencing System for Assessing Relevant Somatic Variants in Solid Tumors
- (2015) Daniel H. Hovelson et al. NEOPLASIA
- Whole-Exome Sequencing of Metastatic Cancer and Biomarkers of Treatment Response
- (2015) Himisha Beltran et al. JAMA Oncology
- Targetable Kinase-Activating Lesions in Ph-like Acute Lymphoblastic Leukemia
- (2015) Kathryn G. Roberts et al. NEW ENGLAND JOURNAL OF MEDICINE
- Analytical and Clinical Validation of a Digital Sequencing Panel for Quantitative, Highly Accurate Evaluation of Cell-Free Circulating Tumor DNA
- (2015) Richard B. Lanman et al. PLoS One
- Frequent STAT5B mutations in γδ hepatosplenic T-cell lymphomas
- (2014) A Nicolae et al. LEUKEMIA
- C11orf95–RELA fusions drive oncogenic NF-κB signalling in ependymoma
- (2014) Matthew Parker et al. NATURE
- Erratum: Corrigendum: Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks
- (2014) Cole Trapnell et al. Nature Protocols
- MLL2 and KDM6A mutations in patients with Kabuki syndrome
- (2013) Noriko Miyake et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART A
- CBFA2T3-GLIS2 fusion transcript is a novel common feature in pediatric, cytogenetically normal AML, not restricted to FAB M7 subtype
- (2013) R. Masetti et al. BLOOD
- The histone H3.3K27M mutation in pediatric glioma reprograms H3K27 methylation and gene expression
- (2013) K.-M. Chan et al. GENES & DEVELOPMENT
- ACMG recommendations for reporting of incidental findings in clinical exome and genome sequencing
- (2013) Robert C. Green et al. GENETICS IN MEDICINE
- Signatures of mutational processes in human cancer
- (2013) Ludmil B. Alexandrov et al. NATURE
- Development and validation of a clinical cancer genomic profiling test based on massively parallel DNA sequencing
- (2013) Garrett M Frampton et al. NATURE BIOTECHNOLOGY
- Exome sequencing identifies secondary mutations of SETBP1 and JAK3 in juvenile myelomonocytic leukemia
- (2013) Hirotoshi Sakaguchi et al. NATURE GENETICS
- Relapse-specific mutations in NT5C2 in childhood acute lymphoblastic leukemia
- (2013) Julia A Meyer et al. NATURE GENETICS
- Activating mutations in the NT5C2 nucleotidase gene drive chemotherapy resistance in relapsed ALL
- (2013) Gannie Tzoneva et al. NATURE MEDICINE
- The molecular biology of WHO Grade II gliomas
- (2013) Nicholas F. Marko et al. Neurosurgical Focus
- PAX-FOXO1fusion status drives unfavorable outcome for children with rhabdomyosarcoma: A children's oncology group report
- (2013) Stephen X. Skapek et al. PEDIATRIC BLOOD & CANCER
- EXCAVATOR: detecting copy number variants from whole-exome sequencing data
- (2013) Alberto Magi et al. GENOME BIOLOGY
- Aberrant patterns of H3K4 and H3K27 histone lysine methylation occur across subgroups in medulloblastoma
- (2012) Adrian M. Dubuc et al. ACTA NEUROPATHOLOGICA
- K27M mutation in histone H3.3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas
- (2012) Dong-Anh Khuong-Quang et al. ACTA NEUROPATHOLOGICA
- Hotspot Mutations in H3F3A and IDH1 Define Distinct Epigenetic and Biological Subgroups of Glioblastoma
- (2012) Dominik Sturm et al. CANCER CELL
- An Inv(16)(p13.3q24.3)-Encoded CBFA2T3-GLIS2 Fusion Protein Defines an Aggressive Subtype of Pediatric Acute Megakaryoblastic Leukemia
- (2012) Tanja A. Gruber et al. CANCER CELL
- Copy Number Gain of 1q25 Predicts Poor Progression-Free Survival for Pediatric Intracranial Ependymomas and Enables Patient Risk Stratification: A Prospective European Clinical Trial Cohort Analysis on Behalf of the Children's Cancer Leukaemia Group (CCLG), Societe Francaise d'Oncologie Pediatrique (SFOP), and International Society for Pediatric Oncology (SIOP)
- (2012) J.-P. Kilday et al. CLINICAL CANCER RESEARCH
- Points to consider in the clinical application of genomic sequencing
- (2012) GENETICS IN MEDICINE
- Association of Age at Diagnosis and Genetic Mutations in Patients With Neuroblastoma
- (2012) Nai-Kong V. Cheung JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks
- (2012) Cole Trapnell et al. Nature Protocols
- The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.
- (2012) Ethan Cerami et al. Cancer Discovery
- FusionMap: detecting fusion genes from next-generation sequencing data at base-pair resolution
- (2011) Huanying Ge et al. BIOINFORMATICS
- Identification of FOXP1 and SNX2 as novel ABL1 fusion partners in acute lymphoblastic leukaemia
- (2011) Thomas Ernst et al. BRITISH JOURNAL OF HAEMATOLOGY
- Delineation of Two Clinically and Molecularly Distinct Subgroups of Posterior Fossa Ependymoma
- (2011) Hendrik Witt et al. CANCER CELL
- Renal Cell Carcinoma in Children and Young Adults: Clinicopathological, Immunohistochemical, and VHL Gene Analysis of 46 Cases With Follow-up
- (2011) Qiu Rao et al. INTERNATIONAL JOURNAL OF SURGICAL PATHOLOGY
- Ollier disease and Maffucci syndrome are caused by somatic mosaic mutations of IDH1 and IDH2
- (2011) M Fernanda Amary et al. NATURE GENETICS
- Somatic mosaic IDH1 and IDH2 mutations are associated with enchondroma and spindle cell hemangioma in Ollier disease and Maffucci syndrome
- (2011) Twinkal C Pansuriya et al. NATURE GENETICS
- Hereditary cancer risk assessment in a pediatric oncology follow-up clinic
- (2011) Sara Knapke et al. PEDIATRIC BLOOD & CANCER
- High-Throughput Detection of Actionable Genomic Alterations in Clinical Tumor Samples by Targeted, Massively Parallel Sequencing
- (2011) Nikhil Wagle et al. Cancer Discovery
- Fusion Gene–Negative Alveolar Rhabdomyosarcoma Is Clinically and Molecularly Indistinguishable From Embryonal Rhabdomyosarcoma
- (2010) Daniel Williamson et al. JOURNAL OF CLINICAL ONCOLOGY
- Medulloblastoma Comprises Four Distinct Molecular Variants
- (2010) Paul A. Northcott et al. JOURNAL OF CLINICAL ONCOLOGY
- Prevalence and prognostic implications of CEBPA mutations in pediatric acute myeloid leukemia (AML): a report from the Children's Oncology Group
- (2009) P. A. Ho et al. BLOOD
- Genomic Analysis Using High-Density Single Nucleotide Polymorphism-Based Oligonucleotide Arrays and Multiplex Ligation-Dependent Probe Amplification Provides a Comprehensive Analysis of INI1/SMARCB1 in Malignant Rhabdoid Tumors
- (2009) E. M. Jackson et al. CLINICAL CANCER RESEARCH
- Histologic subtypes of hepatoblastoma are characterized by differential canonical Wnt and Notch pathway activation in DLK+ precursors
- (2009) Dolores López-Terrada et al. HUMAN PATHOLOGY
- Specific chromosomal imbalances as detected by array CGH in ependymomas in association with tumor location, histological subtype and grade
- (2009) Audrey Rousseau et al. JOURNAL OF NEURO-ONCOLOGY
- Deletion ofIKZF1and Prognosis in Acute Lymphoblastic Leukemia
- (2009) Charles G. Mullighan et al. NEW ENGLAND JOURNAL OF MEDICINE
- An Abundance of Ubiquitously Expressed Genes Revealed by Tissue Transcriptome Sequence Data
- (2009) Daniel Ramsköld et al. PLoS Computational Biology
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