Distinct gene regulatory programs define the inhibitory effects of liver X receptors and PPARG on cancer cell proliferation

Uncoupling Nuclear Receptor LXR and Cholesterol Metabolism in Cancer

(2015) Fabiola Bovenga et al.   Cell Metabolism

Promoter-distal RNA polymerase II binding discriminates active from inactive CCAAT/ enhancer-binding protein beta binding sites

(2015) Daniel Savic et al.   GENOME RESEARCH

Inhibition of Cancer Cell Proliferation by PPARγ Is Mediated by a Metabolic Switch that Increases Reactive Oxygen Species Levels

(2014) Nishi Srivastava et al.   Cell Metabolism

A new dawn for the use of thiazolidinediones in cancer therapy

(2014) Hardik Joshi et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Peroxisome proliferator-activated receptor-γ activation inhibits hepatocellular carcinoma cell invasion by upregulating plasminogen activator inhibitor-1

(2013) Xiaojuan Pang et al.   CANCER SCIENCE

Distinct Properties of Cell-Type-Specific and Shared Transcription Factor Binding Sites

(2013) Jason Gertz et al.   MOLECULAR CELL

PPARγ against Tumors by Different Signaling Pathways

(2013) Zhi Zhang et al.   ONKOLOGIE

Signaling by Nuclear Receptors

(2013) R. Sever et al.   Cold Spring Harbor Perspectives in Biology

The Liver X Receptor Agonist T0901317 Protects Mice from High Fat Diet-Induced Obesity and Insulin Resistance

(2012) Mingming Gao et al.   AAPS Journal

The Role of Peroxisome Proliferator-Activated Receptor-γ in Breast Cancer

(2012) Ioly Kotta-Loizou et al.   Anti-Cancer Agents in Medicinal Chemistry

The oxysterol receptors lxrα and lxrβ suppress proliferation in the colon

(2012) Lise-Lotte Vedin et al.   MOLECULAR CARCINOGENESIS

Transcriptional enhancers in development and disease

(2012) Noboru Sakabe et al.   GENOME BIOLOGY

Modeling gene expression using chromatin features in various cellular contexts

(2012) Xianjun Dong et al.   GENOME BIOLOGY

Functional and Mechanistic Diversity of Distal Transcription Enhancers

(2011) Michael Bulger et al.   CELL

Transposase mediated construction of RNA-seq libraries

(2011) J. Gertz et al.   GENOME RESEARCH

Gene regulatory networks and the role of robustness and stochasticity in the control of gene expression

(2011) L. T. MacNeil et al.   GENOME RESEARCH

Transcription Factor AP1 Potentiates Chromatin Accessibility and Glucocorticoid Receptor Binding

(2011) Simon C. Biddie et al.   MOLECULAR CELL

Coronin 2A mediates actin-dependent de-repression of inflammatory response genes

(2011) Wendy Huang et al.   NATURE

Procedures for large-scale metabolic profiling of serum and plasma using gas chromatography and liquid chromatography coupled to mass spectrometry

(2011) Warwick B Dunn et al.   Nature Protocols

Chemopreventive potential of β-Sitosterol in experimental colon cancer model - an In vitro and In vivo study

(2010) Albert A Baskar et al.   BMC Complementary and Alternative Medicine

Transcriptional Enhancers in Animal Development and Evolution

(2010) Mike Levine   CURRENT BIOLOGY

GREAT improves functional interpretation of cis-regulatory regions

(2010) Cory Y McLean et al.   NATURE BIOTECHNOLOGY

Liver X Receptor activation downregulates AKT survival signaling in lipid rafts and induces apoptosis of prostate cancer cells

(2010) A J C Pommier et al.   ONCOGENE

Enrichment Map: A Network-Based Method for Gene-Set Enrichment Visualization and Interpretation

(2010) Daniele Merico et al.   PLoS One

Estrogen-dependent gallbladder carcinogenesis in LXR -/- female mice

(2010) C. Gabbi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Histone H3K27ac separates active from poised enhancers and predicts developmental state

(2010) M. P. Creyghton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Large Fraction of Extragenic RNA Pol II Transcription Sites Overlap Enhancers

(2010) Francesca De Santa et al.   PLOS BIOLOGY

Differential expression analysis for sequence count data

(2010) Simon Anders et al.   GENOME BIOLOGY

The oxysterol receptor LXR inhibits proliferation of human breast cancer cells

(2009) Lise-Lotte Vedin et al.   CARCINOGENESIS

Differential chromatin marking of introns and expressed exons by H3K36me3

(2009) Paulina Kolasinska-Zwierz et al.   NATURE GENETICS

Coordination of inflammation and metabolism by PPAR and LXR nuclear receptors

(2008) Cynthia Hong et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Androgen Deprivation by Activating the Liver X Receptor

(2008) Jung Hoon Lee et al.   ENDOCRINOLOGY

Tuning gene expression to changing environments: from rapid responses to evolutionary adaptation

(2008) Luis López-Maury et al.   NATURE REVIEWS GENETICS

Model-based Analysis of ChIP-Seq (MACS)

(2008) Yong Zhang et al.   GENOME BIOLOGY