Review
Microbiology
Mahvish Maqbool, Muhammad Sohail Sajid, Muhammad Saqib, Faisal Rasheed Anjum, Muhammad Haleem Tayyab, Hafiz Muhammad Rizwan, Muhammad Imran Rashid, Imaad Rashid, Asif Iqbal, Rao Muhammad Siddique, Asim Shamim, Muhammad Adeel Hassan, Farhan Ahmad Atif, Abdul Razzaq, Muhammad Zeeshan, Kashif Hussain, Rana Hamid Ali Nisar, Akasha Tanveer, Sahar Younas, Kashif Kamran, Sajjad ur Rahman
Summary: Ticks are important vectors for transmitting pathogens to humans, animals, and wildlife. Tick-borne viruses are highly pathogenic and pose a significant threat to public health, especially in resource-poor communities. Understanding tick saliva, host interactions, and control strategies is crucial in preventing tick-borne viral diseases.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Microbiology
Geng Hu, Fachun Jiang, Qin Luo, Kexin Zong, Liyan Dong, Guoyong Mei, Haijun Du, Hongming Dong, Qinqin Song, Juan Song, Zhiqiang Xia, Chen Gao, Jun Han
Summary: Thirty-six strains of 10 RNA viruses belonging to 4 viral families were identified from five tick species in Qingdao, China. A diversity of tick-borne viruses from hares and hedgehogs in Qingdao was found in this study. These findings shed new light on the cross-sea transmission of tick-borne viruses between China and Japan.
MICROBIOLOGY SPECTRUM
(2023)
Article
Immunology
You Zhang, Ben Hu, Bernard Agwanda, Yaohui Fang, Jun Wang, Stephen Kuria, Juan Yang, Moses Masika, Shuang Tang, Jacqueline Lichoti, Zhaojun Fan, Zhengli Shi, Sheila Ommeh, Hualin Wang, Fei Deng, Shu Shen
Summary: This study identified novel tick-borne viruses and new strains of known viruses, some of which were found to potentially cause zoonotic diseases. Transmission patterns of these viruses were analyzed, suggesting various modes of transmission. The findings highlight the threat posed by emerging tick-borne viruses and may inform prevention and control strategies for zoonotic diseases in Kenya and other African countries.
EMERGING MICROBES & INFECTIONS
(2021)
Article
Parasitology
Caitlin A. O'Brien, Bixing Huang, David Warrilow, Jessamine E. Hazlewood, Helle Bielefeldt-Ohmann, Sonja Hall-Mendelin, Cassandra L. Pegg, Jessica J. Harrison, Devina Paramitha, Natalee D. Newton, Benjamin L. Schulz, Andreas Suhrbier, Jody Hobson-Peters, Roy A. Hall
Summary: A subset of Australians bitten by ticks experience chronic and debilitating symptoms that cannot be explained by known pathogenic bacteria. In an effort to understand these symptoms, researchers in Australia are identifying and characterising viruses in ticks. This study successfully characterises five tick-borne viruses and provides insights into their replication and antigenic profiles.
PARASITES & VECTORS
(2022)
Article
Infectious Diseases
Elizabeth Ajema Chebichi Luvai, Leo Uchida, Mya Myat Ngwe Tun, Shingo Inoue, Hu Weiyin, Hiroshi Shimoda, Kouichi Morita, Daisuke Hayasaka
Summary: This study aimed to determine the seroprevalence of tick-borne viruses, including TBEV and newly identified viruses, in wild boar in Nagasaki, Japan. The research revealed the presence of antibodies against KAMV, TFLV, and TBEV in wild boar serum, highlighting the importance of understanding the seroprevalence of these viruses in sentinel animals for disease prevention policies.
TICKS AND TICK-BORNE DISEASES
(2022)
Article
Virology
Xianglong Cai, Xiaojing Cai, Yongkang Xu, Yi Shao, Lian Fu, Xiaoyu Men, Yan Zhu
Summary: This study investigated the geographical distribution of tick species and related viruses in Heilongjiang and Jilin Provinces in Northeast China. Four Ixodidae species were identified, including Ixodes persulcatus, Haemaphysalis japonica, Dermacentor silvarum, and Haemaphysalis concinna. The viral sequences were annotated as Beiji nairovirus, Alongshan virus, bovine parvovirus-2, and tick-associated circovirus. This study provides a basis for further research on tick-borne viruses in northeastern China.
Article
Virology
Michael Amoa-Bosompem, Daisuke Kobayashi, Astri Nur Faizah, Shohei Kimura, Ama Antwi, Esinam Agbosu, Deborah Pratt, Mitsuko Ohashi, Joseph H. Kofi Bonney, Samuel Dadzie, Hiroko Ejiri, Nobuo Ohta, Kyoko Sawabe, Shiroh Iwanaga, Haruhiko Isawa
Summary: This study in Ghana aimed to determine the presence and distribution of ticks infesting dogs and cattle, as well as the tick-borne or tick-associated viruses they carry. A diverse population of ticks infesting cattle, with three genera found, was identified compared to ticks infesting dogs which belong to only one genus. Six phleboviruses and an orthonairovirus were detected in tick pools, with one virus (16GH-T27) most closely related to unclassified phleboviruses found in ticks collected from cattle. The findings contribute to understanding the presence and distribution of ticks and tick-borne viruses in disease prevention and public health.
ARCHIVES OF VIROLOGY
(2022)
Article
Infectious Diseases
Alexander W. Gofton, Kim R. Blasdell, Casey Taylor, Peter B. Banks, Michelle Michie, Emilie Roy-Dufresne, Jacqueline Poldy, Jian Wang, Michael Dunn, Mary Tachedjian, Ina Smith
Summary: Tick-borne zoonoses are emerging globally due to changes in climate and land use. In Australia, the diversity of potentially zoonotic agents carried by ticks and their significance to human and animal health is not well understood. In this study, metatranscriptomics was used to analyze tick and wildlife blood samples in New South Wales, Australia, revealing a wide range of tick-borne microorganisms, including novel putative species. These findings highlight the unique and endemic microbial fauna harbored by Australian ticks and the need for further research on their potential risks to human and animal health.
TRANSBOUNDARY AND EMERGING DISEASES
(2022)
Article
Microbiology
Yu Bai, Yang Li, Wenli Liu, Jing Li, Fengjuan Tian, Lei Liu, Xiaohu Han, Yigang Tong
Summary: In this study, metagenomic analysis of ticks in the border area of Liaoning Province, China, identified viruses related to known diseases, including severe fever with thrombocytopenia syndrome virus (SFTSV) and nairobi sheep disease virus (NSDV). The tick viruses were closely related to the families of Flaviviridae, Parvoviridae, Phenuiviridae, and Rhabdoviridae. The research provided insight into the pathogens carried by ticks in the region, offering epidemiological information for potential outbreaks and serving as a reference for assessing the risk of tick bite infection and exploring virus evolution and transmission mechanisms.
FRONTIERS IN MICROBIOLOGY
(2023)
Article
Multidisciplinary Sciences
Koray Ergunay, Brian P. Bourke, Drew D. Reinbold-Wasson, Mikeljon P. Nikolich, Suppaluck P. Nelson, Laura Caicedo-Quiroga, Nataliya Vaydayko, Giorgi Kirkitadze, Tamar Chunashvili, Lewis S. Long, Jason K. Blackburn, Nora G. Cleary, Cynthia L. Tucker, Yvonne-Marie Linton
Summary: In this study, metagenome-based nanopore sequencing and targeted amplification were used to analyze tick samples from Eastern Europe and the Black Sea region. The study identified the expansion of newly documented tick-borne viral pathogens in Europe and discovered TTV1 virus for the first time on the continent.
SCIENTIFIC REPORTS
(2023)
Article
Biotechnology & Applied Microbiology
Weiyi Li, Rongting Li, Xiaomin Tang, Jinzhi Cheng, Lin Zhan, Zhengling Shang, Jiahong Wu
Summary: Genetic reassortment and recombination among Jingmen viruses associated with ticks and vertebrates complicate their evolutionary relationships and pose a risk to humans.
Article
Endocrinology & Metabolism
A. Salpietro, M. Fusco, M. C. Mercuri, S. Sestito, L. Oreto, G. F. Parisi, G. Ceravolo, F. Borgia, R. De Sarro, I Ceravolo, R. Chimenz, C. Cuppari
Summary: Tick-borne diseases are increasing, with various clinical conditions and symptoms similar to common childhood illnesses. Identifying exposure location, rash features, and tick vectors can help in disease recognition, treatment, and prevention.
JOURNAL OF BIOLOGICAL REGULATORS AND HOMEOSTATIC AGENTS
(2022)
Review
Medicine, General & Internal
Dominic Adam Worku
Summary: Tick-borne encephalitis (TBE) is a viral disease prevalent in large parts of Europe and Asia, characterized by neurological symptoms that can range from mild to severe, and it often leads to long-term morbidity. The pathogenesis of TBE is not fully understood, but factors such as ticks, viral strains, host immune response, and age may contribute to the disease phenotype. The incidence of TBE is increasing and its epidemiology is changing due to global warming.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Infectious Diseases
Sally J. Cutler, Muriel Vayssier-Taussat, Agustin Estrada-Pena, Aleksandar Potkonjak, Andrei D. Mihalca, Herve Zeller
Summary: Although multiple pathogens have been reported to be tick-borne, our understanding of the interactions of these agents within ticks and vertebrate hosts remains limited, especially in humans. Research on co-infections is scarce, and there is a need to further investigate the interactions of pathogen combinations between vertebrate hosts and tick vectors.
TICKS AND TICK-BORNE DISEASES
(2021)
Review
Virology
E. Taylor Stone, Amelia K. Pinto
Summary: The Flaviviridae family consists of diverse arthropod-borne viruses that cause globally relevant diseases in humans. Infection with certain flaviviruses, like West Nile virus, Zika virus, Japanese encephalitis virus, tick-borne encephalitis virus, and Powassan virus, can lead to neuroinvasive diseases such as meningitis or encephalitis. T cells have been identified as a contributor to neuroinflammation, but their role in tick-borne flavivirus encephalitis requires further study. Understanding the involvement of T cells in tick-borne flavivirus encephalitis is crucial for improving vaccine safety and efficacy, as well as developing treatments for human disease.
