Article
Psychiatry
Ryoko Fujikawa, Kumiko Fujii, Yuji Ozeki
Summary: In a patient with bipolar I disorder, the administration of lithium via a nasogastric tube resulted in lower than expected blood lithium concentrations. Crushing and administering lithium tablets through a nasogastric tube can be used for managing mania, but caution should be exercised due to the risk of fluctuations in blood lithium levels.
FRONTIERS IN PSYCHIATRY
(2022)
Article
Nutrition & Dietetics
Chung Y. Hsu, Jung-Nien Lai, Woon-Man Kung, Chao-Hsien Hung, Hei-Tung Yip, Yu-Chen Chang, Cheng-Yu Wei
Summary: Tube feeding, specifically nasogastric tube (NGT) placement, is commonly used for patients with severe swallowing issues. This study in Taiwan aimed to determine the prevalence and outcomes of long-term NGT placement. The results showed that long-term NGT use was associated with a higher risk of comorbidities and mortality.
Review
Geriatrics & Gerontology
Amie Blaszczyk, Nicole Brandt, Jeremy Ashley, Nancy Tuders, Hannah Doles, Richard G. Stefanacci
Summary: Dysphagia, or difficulty swallowing, is common in hospitals and long-term care settings. This review discusses how people with dysphagia can best take their medications and provides recommendations on best practices.
Review
Geriatrics & Gerontology
Amie Blaszczyk, Nicole Brandt, Jeremy Ashley, Nancy Tuders, Hannah Doles, Richard G. Stefanacci
Summary: Dysphagia, or difficulty swallowing, is common in hospitals and long-term care settings. People with dysphagia may have trouble swallowing pills, and this review provides recommendations on the best practices for medication administration. It emphasizes the importance of a coordinated effort from healthcare providers, including physicians, pharmacists, speech-language pathologists, and frontline care staff, to develop an individualized plan for patients with dysphagia.
Article
Infectious Diseases
Aliaa Fouad, Richard Quintiliani, David P. Nicolau, Tomefa E. Asempa
Summary: This study aimed to evaluate the bioavailability of crushed tebipenem tablets administered via nasogastric tube with or without concomitant enteral feeds. Results showed that crushed tebipenem tablets maintained bioequivalence when administered with or without enteral feeds, compared to whole tablet oral administration. Alternative methods of tebipenem administration can be considered depending on patient condition.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
(2023)
Article
Oncology
Li Zhang, Xiuli Zhu, Yurong He, Guiqin Zhang
Summary: The study involving 130 critical patients showed that nasogastric tube nutrition nursing can improve patients' nutritional indicators, decrease the incidence of gastrointestinal complications and adverse events, and increase quality of life scores.
AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH
(2021)
Article
Medicine, General & Internal
Takamichi Kanbayashi, Sonoko Tanaka, Yudai Uchida, Yuki Hatanaka, Masahiro Sonoo
Summary: Nasogastric tube syndrome (NGTS) is a rare but life-threatening complication associated with nasogastric tube (NGT) placement, and the size and type of NGT can affect its development. Immediate removal of NGT can improve symptoms, and choosing the appropriate NGT can prevent recurrence of NGTS.
Article
Pharmacology & Pharmacy
Juseung Lee, Jong-Ju Lee, Seungyeol Lee, Linh Dinh, Hangyu Oh, Sharif Md Abuzar, Jun-Hyun Ahn, Sung-Joo Hwang
Summary: A novel APX SD was prepared, which showed improved solubility and permeability, thus increasing the bioavailability of APX.
Article
Biochemistry & Molecular Biology
Li Zhang, Dewen Kong, Hongjuan Wang, Lingtai Jiao, Xiaoyue Zhao, Junke Song, Dezhi Yang, Haiguang Yang, Shiying Yang, Guanhua Du, Yang Lu
Summary: Novel cocrystals composed of two antithrombotic drugs with poor solubility were developed in this study to improve their solubility, bioavailability, and stability. Compared to physical mixtures and individual drugs, the cocrystals showed significantly enhanced dissolution behavior and increased bioavailability. The study provides a novel approach to overcome the limitations of drug combinations.
Article
Health Care Sciences & Services
Vasiliki Tsolaki, George E. Zakynthinos, Paris Zygoulis, Fotini Bardaka, Aikaterini Malita, Vasileios Aslanidis, Epaminondas Zakynthinos, Demosthenes Makris
Summary: Ultrasonographic confirmation of nasogastric tube (NGT) placement is feasible and accurate in COVID-19 ARDS patients, providing a high level of accuracy and sensitivity in post-insertion evaluation.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Tim Torsy, Renee Saman, Kurt Boeykens, Mats Eriksson, Sofie Verhaeghe, Dimitri Beeckman
Summary: The study found that high body mass index, male sex, and the absence of a guidewire inside the nasogastric tube during chest X-ray were associated with a risk of insufficient visibility of the tube.
EUROPEAN RADIOLOGY
(2021)
Article
Microbiology
Amit Desai, Melanie Helmick, Nakyo Heo, Selina Moy, Stephen Stanhope, Ronald Goldwater, Nancy Martin
Summary: For critically ill patients with invasive fungal infections, a nasogastric tube can be an alternative route for administration of isavuconazonium sulfate. This study showed bioequivalence between intravenous administration of isavuconazole via NG tube and oral administration, with both routes being well tolerated. The pharmacokinetic parameters were similar between the two routes of administration, supporting the feasibility of NG tube administration in patients.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
(2021)
Article
Critical Care Medicine
Nicola Mumoli, Jose Vitale, Alberto Pagnamenta, Daniela Mastroiacovo, Marco Cei, Fulvio Pomero, Matteo Giorgi-Pierfranceschi, Lucia Giuntini, Cesare Porta, Riccardo Capra, Antonino Mazzone, Francesco Dentali
Summary: Bedside abdominal ultrasound (BAU) shows good positive predictive value in confirming the correct placement of nasogastric tubes (NGTs) compared to chest radiography, but caution is necessary due to its suboptimal specificity.
Review
Critical Care Medicine
Kurt Boeykens, Tom Holvoet, Ivo Duysburgh
Summary: Nasogastric feeding tubes are commonly used in healthcare settings, but misplacement can lead to serious complications. The current method of determining insertion length is often too short, resulting in incorrect tip position. New, safer methods need to be developed and more robust evidence is needed to improve the practice. Verifying correct gastric tip positioning after blind placement is crucial to prevent complications.
Article
Oncology
Noriyuki Hirahara, Takeshi Matsubara, Shunsuke Kaji, Yuki Uchida, Tetsu Yamamoto, Ryoji Hyakudomi, Kiyoe Takai, Kazunari Ishitobi, Yoshitsugu Tajima
Summary: A safe and simple technique for placing a nasogastric tube during esophagogastrostomy was developed in this study, which proved to be successful in all cases.
WORLD JOURNAL OF SURGICAL ONCOLOGY
(2021)
Article
Ecology
Qingqiu Zhou, Xiaoli Wang, Ying Wu, Zhe Chen, Debao Li, Yuanhu Shao, Jianping Wu
Summary: Long-term nitrogen deposition can change the abundance and community composition of soil nematodes, affecting the soil food web and biogeochemical cycling. In Cunninghamia lanceolata forest, nitrogen addition increased the abundance of bacterial-feeding nematodes but reduced the abundance of plant-feeding nematodes. Furthermore, nitrogen addition indirectly affected the abundances of bacterial, fungal, and plant-feeding nematodes via changes in soil nutrients, soil water content, and pH.
Correction
Environmental Sciences
Fenghua Li, Xianqi Zhao, Yanni Jiao, Xinglan Duan, Lianlong Yu, Fengjia Zheng, Xiaolin Wang, Lin Wang, Jia-Sheng Wang, Xiulan Zhao, Tianliang Zhang, Wei Li, Jun Zhou
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Energy & Fuels
Xu Li, Jiaqi Li, Xiaohong Wang, Lijun Yang, Hong Xu, Jinxiang Dong
Summary: Despite progress in purifying C5-C9 linear alpha-olefins from Fischer-Tropsch synthesis products, the separation of olefins and paraffins with the same carbon number hampers their industrial development. This study proposes a process that uses zirconocene/methylalumoxane catalyst for selective dimerization of linear alpha-olefins, followed by distillation and catalytic conversion into branched-chain sulfonate surfactants. The resulting surfactants outperform commercially used linear alkylbenzene sulfonate in terms of surfactant properties and detergency performance.
Article
Chemistry, Multidisciplinary
Yaqian Feng, Peipei Chen, Chuyue Huang, Hailan Chen, Ruolan Fan, Lu Wang, Shaohua Xu, Wen Xu, Zhimin Fan, Wei Xu
Summary: Celastrol was transformed by Streptomyces olivaceus CICC 23628, resulting in the isolation of two new friedelanes derivatives (CEL-1 and CEL-2) as metabolites. Their structures were elucidated through NMR and HR-MS analysis. In vitro studies demonstrated that CEL-2 could induce apoptosis and block the cell cycle in HCT-116 cells. Western blotting analysis showed that CEL-2 inhibited STAT3 phosphorylation and downstream gene expression. Moreover, SPR analysis confirmed the direct binding of CEL-2 with STAT3 protein. These findings suggest that CEL-2 may have potential as an anti-colorectal cancer agent by inhibiting STAT3 and inducing apoptosis and cell cycle arrest.
ARABIAN JOURNAL OF CHEMISTRY
(2023)
Article
Medical Laboratory Technology
Jiale Xiang, Jiguang Peng, Xiangzhong Sun, Zibin Lin, Dongdong Li, Haodong Ye, Sibao Wang, Yushi Bai, Xiaohong Wang, Peina Du, Ya Gao, Jun Sun, Silin Pan, Zhiyu Peng
Summary: In this study, we developed a reliable method to accurately determine the copy number of STRC based on standard short-read genome sequencing data, which has clinical significance in the screening and diagnosis of genetic hearing loss. Our population analysis revealed that 5.22% of the general population has copy number changes in STRC, almost half of which are clinically significant, including heterozygous and homozygous deletions of STRC. Additionally, we provided population-based evidence of pseudogene-mediated gene conversions between STRC and STRCP1.
CLINICAL CHEMISTRY
(2023)
Article
Oncology
Yu-Chun Song, Jie Kong, Na Li, Xiao-Lei Liu, Xiao-Hong Li, Long-Yu Zhu, Yu-Wei Wang, Hui Fang, Hao Jing, Yu Tang, Ye-Xiong Li, Jun Zhang, Xiao-Hong Wang, Shu-Lian Wang
Summary: This study evaluated and compared the outcomes of supraclavicular lymph node dissection plus radiotherapy and radiotherapy alone for patients with synchronous ipsilateral supraclavicular lymph node metastasis. The results showed that supraclavicular lymph node dissection did not improve survival rates for patients, especially for those in the intermediate and high-risk groups, who still had issues with distant metastasis.
RADIOTHERAPY AND ONCOLOGY
(2023)
Article
Microbiology
Masafumi Yoshinaga, Guodong Niu, Kunie Yoshinaga-Sakurai, Venkadesh S. S. Nadar, Xiaohong Wang, Barry P. P. Rosen, Jun Li
Summary: Malaria caused by Plasmodium parasites is a major disease with high morbidity and mortality rates. The Plasmodium parasite has a complex life cycle involving both human and mosquito hosts. Most current antimalarials only target the blood stage of the parasite, requiring the development of new drugs that can target multiple stages of the life cycle.
Article
Engineering, Environmental
Yunping Tong, Xiaolei Wang, Xinghao Wang, Zhaoyue Sun, Guodong Fang, Juan Gao
Summary: The concomitant pollution of arsenic and antibiotics has been commonly observed in recent environments, and their behavior may differ from when they exist individually. Colloidal ferric hydroxide (CFH) is found ubiquitously in various environments and in this study, it was shown to facilitate the degradation of oxytetracycline (OTC) and the reduction of Fe(III) to Fe(II). Under oxygen-rich conditions, reactive oxygen species (ROS) such as (OH)-O• and O2•- were generated through the reactions between dissolved oxygen (DO) and Fe(II). It was found that (OH)-O• played a dominant role in the oxidation of As(III). Furthermore, the oxidation of As(III) to As(V) resulted in the formation of ferric arsenate, which significantly reduced the risks of As(III) in the environment. Similar transformations were also observed with other iron oxides and different antibiotics. These findings contribute to our understanding of the role of organic pollutants in combined contamination.
ACS ES&T ENGINEERING
(2023)
Article
Fisheries
Qian Duan, Qi Luo, Qian Tang, Lei Deng, Renyi Zhang, Yanping Li
Summary: In this study, the full-length transcriptome and transcriptome of Schizothorax lissolabiatus were generated using PacBio single-molecule real-time (SMRT) sequencing and Illumina sequencing, respectively. The study identified Toll-like receptor genes (TLRs) in S. lissolabiatus and showed their classification into six families. This research contributes to the understanding of the evolutionary history of immune-related genes and the TLR gene family in S. lissolabiatus.
FISH & SHELLFISH IMMUNOLOGY
(2023)
Article
Chemistry, Applied
Xia Zhang, Yu Tian, Jinjin Xing, Qi Wang, Ying Liang, Jinshui Wang
Summary: This study investigated the effects of Konjac glucomannan (KGM) on the aggregation patterns and structural properties of weak, middle, and strong gluten. The results revealed that 10% KGM substitution resulted in decreased aggregation energy for middle and strong gluten, but increased for weak gluten. Additionally, 10% KGM enhanced the aggregation of glutenin macropolymer (GMP) in weak gluten, but suppressed it in middle and strong gluten. Furthermore, 10% KGM induced a transition from alpha-helix to beta-sheet in weak gluten, while causing more random-coil structures in middle and strong gluten. The network of weak gluten became more continuous with 10% KGM, whereas it was severely disrupted in middle and strong gluten.
Article
Engineering, Environmental
Ning Chen, Yu Zeng, Tai Li, Peixin Cui, Dionysios D. Dionysiou, Xiaolei Wang, Cun Liu, Guodong Fang, Chengcheng Ding, Yuan Zhao, Juan Gao, Yujun Wang, Dongmei Zhou
Summary: Phosphorus and cobalt co-doped C3N5 (Co-xP-C3N5) has been developed for peroxymonosulfate (PMS) activation and 2,4,4'-trichlorobiphenyl (PCB28) degradation. Phosphorus doping induces the formation of Co-P and Co-N-P species, which increase the content of coordinated Co and improve catalytic performance. This finding provides a new strategy for enhancing the performance of single atom-based catalysts.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Article
Engineering, Environmental
Bo Fan, Bingnan Zhou, Si Chen, Fengxiao Zhu, Bo Chen, Zhimin Gong, Xiaolei Wang, Changyin Zhu, Dongmei Zhou, Feng He, Shixiang Gao
Summary: This study proposed a new synthesis method for preparing Cu-Fe bimetals (Cu-Febm (CuSO4)) and found that the formation of Fe0/FeSx structure compensated for the negative effect of Cu2O on the activity of Cu-Febm (CuSO4) particles. The Cu-Febm (CuSO4) bimetals showed great potential for the removal of chlorinated hydrocarbons in water.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Article
Multidisciplinary Sciences
Xiaolei Wang, Wenbiao Ma, Shengxian Guo, Yajun Xi
Summary: This paper introduces the theory of foundation balance axis correction and the corresponding determination method in the method of rectifying the inclination of inclined buildings. The analysis of the correction effect is conducted using software, providing technical support.
ARABIAN JOURNAL FOR SCIENCE AND ENGINEERING
(2023)
Article
Engineering, Electrical & Electronic
Xiaorong Wang, Yundong Yu, Xiaohe Yan, Nian Liu
Summary: This study proposes a strategy for renewable energy communities to rent energy storage (ES) and participate in the frequency regulation market (FRM). A rental model is built considering capacity rental costs and ES using costs. The results demonstrate that under different rental and market prices, the renewable energy communities can effectively choose the optimal rental strategy and increase their profits.
Review
Obstetrics & Gynecology
Man Di, Xiaohong Wang, Jing Wu, Hongya Yang
Summary: Delayed start GnRH antagonist and microdose GnRH agonist are the two superior regimens in the treatment of poor ovarian response, providing favorable clinical outcomes.
ARCHIVES OF GYNECOLOGY AND OBSTETRICS
(2023)