期刊
CONTACT LENS & ANTERIOR EYE
卷 39, 期 3, 页码 210-216出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.clae.2016.01.008
关键词
Tinted soft contact lenses; Focused ion beam scanning electron microscopy; Atomic force microscopy; Pigment location; Surface roughness
资金
- grant of the Korean Health Technology R & D Project, Ministry of Health & Welfare, Republic of Korea [HI14C2044]
- Ministry of Food and Drug Safety (Seoul, Korea) [14172MFDS379]
Purpose: The purpose of this study was to investigate efficient methods to evaluate the pigment layer location of tinted soft contact lenses and to assess various lens products on the market using those methods. Methods: Two types of tinted soft contact lenses with known pigment location embedded or back surface were manufactured and examined. Light microscopy (LM), focused ion beam milling and scanning electron microscopy (FIB-SEM), and Fourier-domain optical coherence tomography (FD-OCT) were used to examine the pigment layer. Lens surface roughness was also measured using atomic force microscopy. In the second part of the experiment, pigment location and surface roughness of a clear lens (Lens A) and eight commercially-available tinted soft contact lenses (Lens B-I) were evaluated using FIB-SEM and FD-OCT. Results: Pigment location could be reliably determined with FIB-SEM and FD-OCT. With LM, 40% of the lens sections were broken or deformed during slide preparation. The pigment particles in Lens B were buried below the front surface and there were no significant differences of roughness between the front and back surfaces. However, all tinted lenses with surface pigment had significant difference of roughness between front and back surfaces at the pigmented area. Conclusion: The FIB-SEM and FD-OCT could reliably locate the pigment layer of tinted soft contact lenses. In addition, lens surface roughness was influenced by pigment layer location. (C) 2016 British Contact Lens Association. Published by Elsevier Ltd. All rights reserved.
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