Paeoniflorin protects diabetic mice against myocardial ischemic injury via the transient receptor potential vanilloid 1/calcitonin gene-related peptide pathway

The 2015 IWGDF guidance documents on prevention and management of foot problems in diabetes: development of an evidence-based global consensus

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Spinal IL-33/ST2 Signaling Contributes to Neuropathic Pain via Neuronal CaMKII–CREB and Astroglial JAK2–STAT3 Cascades in Mice

(2015) Shenbin Liu et al.   ANESTHESIOLOGY

Tong Luo Jiu Nao ameliorates Aβ1–40-induced cognitive impairment on adaptive behavior learning by modulating ERK/CaMKII/CREB signaling in the hippocampus

(2015) Zhe Shi et al.   BMC Complementary and Alternative Medicine

Successful metabolic adaptations leading to the prevention of high fat diet-induced murine cardiac remodeling

(2015) Nathan W. Roberts et al.   Cardiovascular Diabetology

Activation of TRPV1 channel by dietary capsaicin improves visceral fat remodeling through connexin43-mediated Ca2+ Influx

(2015) Jian Chen et al.   Cardiovascular Diabetology

Low-density-lipoprotein cholesterol concentrations and risk of incident diabetes: epidemiological and genetic insights from the Framingham Heart Study

(2015) Charlotte Andersson et al.   DIABETOLOGIA

Immunoregulatory Effects of Paeoniflorin Exerts Anti-asthmatic Effects via Modulation of the Th1/Th2 Equilibrium

(2015) Tianzhu Zhang et al.   INFLAMMATION

Paeoniflorin inhibition of 6-hydroxydopamine-induced apoptosis in PC12 cells via suppressing reactive oxygen species-mediated PKCδ/NF-κB pathway

(2015) H. Dong et al.   NEUROSCIENCE

Preconditioning with glycyrrhizic, ferulic, paeoniflorin, cinnamic prevents rat hearts from ischemia/reperfusion injury via endothelial nitric oxide pathway

(2015) Guo-Ping Zhao et al.   Pharmacognosy Magazine

TRPV1 Pain Receptors Regulate Longevity and Metabolism by Neuropeptide Signaling

(2014) Céline E. Riera et al.   CELL

Neuroimmunological communication via CGRP promotes the development of a regulatory phenotype in TLR4-stimulated macrophages

(2014) Mariona Baliu-Piqué et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Simultaneous determination of paeoniflorin, albiflorin, ferulic acid, tetrahydropalmatine, protopine, typhaneoside, senkyunolide I in Beagle dogs plasma by UPLC–MS/MS and its application to a pharmacokinetic study after Oral Administration of Shaofu Zhuyu Decoction

(2014) Xiaochen Huang et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Shensong Yangxin Capsule prevents diabetic myocardial fibrosis by inhibiting TGF-β1/Smad signaling

(2014) Nannan Shen et al.   JOURNAL OF ETHNOPHARMACOLOGY

Lipoprotein lipase activity is required for cardiac lipid droplet production

(2014) Chad M. Trent et al.   JOURNAL OF LIPID RESEARCH

Autophagy Is Involved in the Cardioprotection Effect of Remote Limb Ischemic Postconditioning on Myocardial Ischemia/Reperfusion Injury in Normal Mice, but Not Diabetic Mice

(2014) Zhihua Han et al.   PLoS One

Pharmacological correction of obesity-induced autophagy arrest using calcium channel blockers

(2014) Hwan-Woo Park et al.   Nature Communications

Concise Review: Diabetes, the Bone Marrow Niche, and Impaired Vascular Regeneration

(2014) Gian Paolo Fadini et al.   Stem Cells Translational Medicine

Paeoniflorin, a monoterpene glycoside, attenuates lipopolysaccharide-induced neuronal injury and brain microglial inflammatory response

(2013) Kyong-Nyon Nam et al.   BIOTECHNOLOGY LETTERS

Paeoniflorin inhibits inflammatory responses in mice with allergic contact dermatitis by regulating the balance between inflammatory and anti-inflammatory cytokines

(2013) Chun Wang et al.   INFLAMMATION RESEARCH

Disturbance of Intracellular Calcium Homeostasis and CaMKII/CREB Signaling is Associated with Learning and Memory Impairments Induced by Chronic Aluminum Exposure

(2013) Biao Wang et al.   NEUROTOXICITY RESEARCH

Myocardial Ablation of G Protein–Coupled Receptor Kinase 2 (GRK2) Decreases Ischemia/Reperfusion Injury through an Anti-Intrinsic Apoptotic Pathway

(2013) Qian Fan et al.   PLoS One

Paeoniflorin Inhibits Pulmonary Artery Smooth Muscle Cells Proliferation via Upregulating A2B Adenosine Receptor in Rat

(2013) Guoqing Qian et al.   PLoS One

Inhibition of Fas-Associated Death Domain-Containing Protein (FADD) Protects against Myocardial Ischemia/Reperfusion Injury in a Heart Failure Mouse Model

(2013) Qian Fan et al.   PLoS One

An Anthelmintic Drug, Pyrvinium Pamoate, Thwarts Fibrosis and Ameliorates Myocardial Contractile Dysfunction in a Mouse Model of Myocardial Infarction

(2013) Motoaki Murakoshi et al.   PLoS One

Essential role of transient receptor potential vanilloid type 1 in evodiamine-mediated protection against atherosclerosis

(2012) J. Wei et al.   Acta Physiologica

Functional interactions between NMDA receptors and TRPV1 in trigeminal sensory neurons mediate mechanical hyperalgesia in the rat masseter muscle

(2012) Jongseok Lee et al.   PAIN

Glucose-6-Phosphate Dehydrogenase and NADPH Redox Regulates Cardiac Myocyte L-Type Calcium Channel Activity and Myocardial Contractile Function

(2012) Dhwajbahadur K. Rawat et al.   PLoS One

Catching the engram: strategies to examine the memory trace

(2012) Masanori Sakaguchi et al.   Molecular Brain

Up-regulation of calcitonin gene-related peptide protects streptozotocin-induced diabetic hearts from ischemia/reperfusion injury

(2011) Liang-rong Zheng et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Transplanted Induced Pluripotent Stem Cells Improve Cardiac Function and Induce Neovascularization in the Infarcted Hearts of db/db Mice

(2011) Binbin Yan et al.   MOLECULAR PHARMACEUTICS

Cardioprotection by ischemic postconditioning is lost in isolated perfused heart from diabetic rats: Involvement of transient receptor potential vanilloid 1, calcitonin gene-related peptide and substance P

(2011) Jing-Yi Ren et al.   REGULATORY PEPTIDES

Natural compounds from traditional medicinal herbs in the treatment of cerebral ischemia/reperfusion injury

(2010) Peng-fei Wu et al.   ACTA PHARMACOLOGICA SINICA

Activation of CaMKII and ERK1/2 contributes to the time-dependent potentiation of Ca2+ response elicited by repeated application of capsaicin in rat DRG neurons

(2010) Xiulin Zhang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Enhanced postmyocardial infarction fibrosis via stimulation of the transforming growth factor-β-Smad2 signaling pathway: role of transient receptor potential vanilloid type 1 channels

(2010) Wei Huang et al.   JOURNAL OF HYPERTENSION

Acid Activation of Trpv1 Leads to an Up-Regulation of Calcitonin Gene-related Peptide Expression in Dorsal Root Ganglion Neurons via the CaMK-CREB Cascade: A Potential Mechanism of Inflammatory Pain

(2010) Masako Nakanishi et al.   MOLECULAR BIOLOGY OF THE CELL

Calcitonin gene-related peptide as a regulator of neuronal CaMKII–CREB, microglial p38–NFκB and astroglial ERK–Stat1/3 cascades mediating the development of tolerance to morphine-induced analgesia

(2010) Zhiyong Wang et al.   PAIN

Paeoniflorin ameliorates schistosomiasis liver fibrosis through regulating IL-13 and its signalling molecules in mice

(2010) XIAOYUE LI et al.   PARASITOLOGY

Calcitonin gene-related peptide enhances CREB phosphorylation and attenuates tau protein phosphorylation in rat brain during focal cerebral ischemia/reperfusion

(2009) Zheng-Hong Zhang et al.   BIOMEDICINE & PHARMACOTHERAPY

Decreased Expression of Transient Receptor Potential Vanilloid 1 Impaires the Postischemic Recovery of Diabetic Mouse Hearts

(2009) Zhonghai Wei et al.   CIRCULATION JOURNAL

Transcription Factors in Long-Term Memory and Synaptic Plasticity

(2009) Cristina M. Alberini   PHYSIOLOGICAL REVIEWS

Paeoniflorin protects RAW 264.7 macrophages from LPS-induced cytotoxicity and genotoxicity

(2009) In Deok Kim et al.   TOXICOLOGY IN VITRO

Low dose cyclophosphamide rescues myocardial function from ischemia-reperfusion in rats☆

(2008) Jianhua Zhu et al.   EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY

Transient Receptor Potential Vanilloid Gene Deletion Exacerbates Inflammation and Atypical Cardiac Remodeling After Myocardial Infarction

(2008) Wei Huang et al.   HYPERTENSION

Paeoniflorin suppresses inflammatory mediator production and regulates G protein-coupled signaling in fibroblast – like synoviocytes of collagen induced arthritic rats

(2008) L.-L. Zhang et al.   INFLAMMATION RESEARCH