Discovery of new MD2 inhibitor from chalcone derivatives with anti-inflammatory effects in LPS-induced acute lung injury
出版年份 2016 全文链接
标题
Discovery of new MD2 inhibitor from chalcone derivatives with anti-inflammatory effects in LPS-induced acute lung injury
作者
关键词
-
出版物
Scientific Reports
Volume 6, Issue 1, Pages -
出版商
Springer Nature
发表日期
2016-04-27
DOI
10.1038/srep25130
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- MD-2 as the target of a novel small molecule, L6H21, in the attenuation of LPS-induced inflammatory response and sepsis
- (2015) Yi Wang et al. BRITISH JOURNAL OF PHARMACOLOGY
- The Immunomodulatory and Therapeutic Effects of Mesenchymal Stromal Cells for Acute Lung Injury and Sepsis
- (2015) Mirabelle S. H. Ho et al. JOURNAL OF CELLULAR PHYSIOLOGY
- The antibody response against human and chimeric anti-TNF therapeutic antibodies primarily targets the TNF binding region
- (2014) K A van Schie et al. ANNALS OF THE RHEUMATIC DISEASES
- TI-I-174, a Synthetic Chalcone Derivative, Suppresses Nitric Oxide Production in Murine Macrophages via Heme Oxygenase-1 Induction and Inhibition of AP-1
- (2014) Mi Jin Kim et al. Biomolecules & Therapeutics
- Targeting myeloid differentiation 2 for treatment of sepsis
- (2014) Guangjie Duan Frontiers in Bioscience-Landmark
- Recognition of LPS by TLR4: Potential for Anti-Inflammatory Therapies
- (2014) Reindert Nijland et al. Marine Drugs
- Biological evaluation of synthetic chalcone and flavone derivatives as anti-inflammatory agents
- (2014) Nelly Mateeva et al. MEDICINAL CHEMISTRY RESEARCH
- Discovery and evaluation of piperid-4-one-containing mono-carbonyl analogs of curcumin as anti-inflammatory agents
- (2013) Jianzhang Wu et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Suppression of Toll-like receptor 4 activation by endogenous oxidized phosphatidylcholine, KOdiA-PC by inhibiting LPS binding to MD2
- (2013) Min Jin Kim et al. INFLAMMATION RESEARCH
- Effect of Eritoran, an Antagonist of MD2-TLR4, on Mortality in Patients With Severe Sepsis
- (2013) Steven M. Opal et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Inflammasome-regulated Cytokines Are Critical Mediators of Acute Lung Injury
- (2012) Tamás Dolinay et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Inhibition of LPS binding to MD-2 co-receptor for suppressing TLR4-mediated expression of inflammatory cytokine by 1-dehydro-10-gingerdione from dietary ginger
- (2012) Sun Hong Park et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Suppression of Toll-like receptor 4 activation by caffeic acid phenethyl ester is mediated by interference of LPS binding to MD2
- (2012) So Young Kim et al. BRITISH JOURNAL OF PHARMACOLOGY
- Exploring Pharmacological Significance of Chalcone Scaffold: A Review
- (2012) N. K. Sahu et al. CURRENT MEDICINAL CHEMISTRY
- Interleukin-6: from an inflammatory marker to a target for inflammatory diseases
- (2012) Mercedes Rincon TRENDS IN IMMUNOLOGY
- Multiple organ failure in sepsis: prognosis and role of systemic inflammatory response
- (2011) Thierry Gustot Current Opinion in Critical Care
- MD-2 as the Target of Nonlipid Chalcone in the Inhibition of Endotoxin LPS-Induced TLR4 Activity
- (2011) Eunmiri Roh et al. JOURNAL OF INFECTIOUS DISEASES
- Evaluation and Discovery of Novel Synthetic Chalcone Derivatives as Anti-Inflammatory Agents
- (2011) Jianzhang Wu et al. JOURNAL OF MEDICINAL CHEMISTRY
- Myeloid differentiation 2 as a therapeutic target of inflammatory disorders
- (2011) Sun Hong Park et al. PHARMACOLOGY & THERAPEUTICS
- Pharmacotherapy for Prevention and Treatment of Acute Respiratory Distress Syndrome
- (2010) Karen J. Bosma et al. DRUGS
- Synthesis and anti-inflammatory evaluation of novel mono-carbonyl analogues of curcumin in LPS-stimulated RAW 264.7 macrophages
- (2010) Chengguang Zhao et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Xanthohumol and Related Prenylated Flavonoids Inhibit Inflammatory Cytokine Production in LPS-Activated THP-1 Monocytes: Structure-Activity Relationships andIn SilicoBinding to Myeloid Differentiation Protein-2 (MD-2)
- (2010) Michael Peluso et al. PLANTA MEDICA
- Free Thiol Group of MD-2 as the Target for Inhibition of the Lipopolysaccharide-induced Cell Activation
- (2009) Mateja Manček-Keber et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The structural basis of lipopolysaccharide recognition by the TLR4–MD-2 complex
- (2009) Beom Seok Park et al. NATURE
- MD-2–Dependent Pulmonary Immune Responses to Inhaled Lipooligosaccharides
- (2008) Suzana Hađina et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- LPS/TLR4 signal transduction pathway
- (2008) Yong-Chen Lu et al. CYTOKINE
- Ghrelin prevents doxorubicin-induced cardiotoxicity through TNF-alpha/NF-κB pathways and mitochondrial protective mechanisms
- (2008) Zhiwei Xu et al. TOXICOLOGY
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