标题
Regulation of ABC transporters at the blood-brain barrier
作者
关键词
-
出版物
CLINICAL PHARMACOLOGY & THERAPEUTICS
Volume 97, Issue 4, Pages 395-403
出版商
Wiley
发表日期
2015-03-17
DOI
10.1002/cpt.64
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Physiology and Pathophysiology of the Blood-Brain Barrier
- (2016) Gwen McCaffrey et al. JOURNAL OF INVESTIGATIVE MEDICINE
- CNS Transporters and Drug Delivery in Epilepsy
- (2014) Heidrun Potschka et al. CURRENT PHARMACEUTICAL DESIGN
- The Cross-Talk between Canonical and Non-Canonical Wnt-Dependent Pathways Regulates P-Glycoprotein Expression in Human Blood–Brain Barrier Cells
- (2014) Martha L Pinzón-Daza et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Nrf2 Upregulates ATP Binding Cassette Transporter Expression and Activity at the Blood-Brain and Blood-Spinal Cord Barriers
- (2014) X. Wang et al. JOURNAL OF NEUROSCIENCE
- Estrogen biology: New insights into GPER function and clinical opportunities
- (2014) Eric R. Prossnitz et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Complex Interplay between the P-Glycoprotein Multidrug Efflux Pump and the Membrane: Its Role in Modulating Protein Function
- (2014) Frances Jane Sharom Frontiers in Oncology
- Why Clinical Modulation of Efflux Transport at the Human Blood–Brain Barrier Is Unlikely: The ITC Evidence-Based Position
- (2013) J C Kalvass et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Signaling Pathways that Regulate Basal ABC Transporter Activity at the Blood- Brain Barrier
- (2013) David Miller et al. CURRENT PHARMACEUTICAL DESIGN
- Blood–brain barrier structure and function and the challenges for CNS drug delivery
- (2013) N. Joan Abbott JOURNAL OF INHERITED METABOLIC DISEASE
- In vivoinduction of P-glycoprotein expression at the mouse blood-brain barrier: an intracerebral microdialysis study
- (2013) Gary N. Y. Chan et al. JOURNAL OF NEUROCHEMISTRY
- Quantitative fluorescence microscopy provides high resolution imaging of passive diffusion and P-gp mediated efflux at the in vivo blood–brain barrier
- (2013) Rajendar K. Mittapalli et al. JOURNAL OF NEUROSCIENCE METHODS
- Dynamic Regulation of P-glycoprotein in Human Brain Capillaries
- (2013) Janine Avemary et al. MOLECULAR PHARMACEUTICS
- Role of nuclear receptors in the regulation of drug transporters in the brain
- (2013) Gary N.Y. Chan et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Role of ABC Transporters in the Pathogenesis of Alzheimer’s Disease
- (2012) Alaa H. Abuznait et al. ACS Chemical Neuroscience
- Estrogen regulation of Dkk1 and Wnt/β-Catenin signaling in neurodegenerative disease
- (2012) Erin L. Scott et al. BRAIN RESEARCH
- Hurdles with Using In Vitro Models to Predict Human Blood-brain Barrier Drug Permeability: A Special Focus on Transporters and Metabolizing Enzymes
- (2012) Ramzi Shawahna et al. CURRENT DRUG METABOLISM
- Do ATP-Binding Cassette Transporters Cause Pharmacoresistance in Epilepsy? Problems and Approaches in Determining which Antiepileptic Drugs are Affected
- (2012) Wolfgang Loscher et al. CURRENT PHARMACEUTICAL DESIGN
- Breast Cancer Resistance Protein and P-Glycoprotein in Brain Cancer: Two Gatekeepers Team Up
- (2012) Sagar Agarwal et al. CURRENT PHARMACEUTICAL DESIGN
- ABC Transporter Function and Regulation at the Blood–Spinal Cord Barrier
- (2012) Christopher R Campos et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Mrp1 is Essential for Sphingolipid Signaling to P-Glycoprotein in Mouse Blood–Brain and Blood–Spinal Cord Barriers
- (2012) Tara A Cartwright et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- P-glycoprotein trafficking at the blood-brain barrier altered by peripheral inflammatory hyperalgesia
- (2012) Gwen McCaffrey et al. JOURNAL OF NEUROCHEMISTRY
- 1α,25-Dihydroxyvitamin D3-liganded vitamin D receptor increases expression and transport activity of P-glycoprotein in isolated rat brain capillaries and human and rat brain microvessel endothelial cells
- (2012) Matthew R. Durk et al. JOURNAL OF NEUROCHEMISTRY
- P-Glycoprotein, Breast Cancer Resistance Protein, Organic Anion Transporter 3, and Transporting Peptide 1a4 during Blood–Brain Barrier Maturation: Involvement of Wnt/β-Catenin and Endothelin-1 Signaling
- (2012) Rania Harati et al. MOLECULAR PHARMACEUTICS
- Derivation of blood-brain barrier endothelial cells from human pluripotent stem cells
- (2012) Ethan S Lippmann et al. NATURE BIOTECHNOLOGY
- Selective increase of two ABC drug efflux transporters at the blood–spinal cord barrier suggests induced pharmacoresistance in ALS
- (2012) Michael R. Jablonski et al. NEUROBIOLOGY OF DISEASE
- Targeting blood-brain barrier sphingolipid signaling reduces basal P-glycoprotein activity and improves drug delivery to the brain
- (2012) R. E. Cannon et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Emerging roles of Nrf2 and phase II antioxidant enzymes in neuroprotection
- (2012) Meijuan Zhang et al. PROGRESS IN NEUROBIOLOGY
- Role of CNS efflux drug transporters in antiepileptic drug delivery: Overcoming CNS efflux drug transport
- (2011) Heidrun Potschka ADVANCED DRUG DELIVERY REVIEWS
- Evolution of ABC transporters by gene duplication and their role in human disease
- (2011) Karobi Moitra et al. BIOLOGICAL CHEMISTRY
- Liver X Receptor Activation Enhances Blood-Brain Barrier Integrity in the Ischemic Brain and Increases the Abundance of ATP-Binding Cassette Transporters ABCB1 and ABCC1 on Brain Capillary Cells
- (2011) Ayman ElAli et al. BRAIN PATHOLOGY
- PET and SPECT Radiotracers to Assess Function and Expression of ABC Transporters In Vivo
- (2011) Severin Mairinger et al. CURRENT DRUG METABOLISM
- ABC Transporters in the CNS – An Inventory
- (2011) A. M.S. Hartz et al. CURRENT PHARMACEUTICAL BIOTECHNOLOGY
- Quantitative targeted absolute proteomics of human blood-brain barrier transporters and receptors
- (2011) Yasuo Uchida et al. JOURNAL OF NEUROCHEMISTRY
- Transcriptomic and Quantitative Proteomic Analysis of Transporters and Drug Metabolizing Enzymes in Freshly Isolated Human Brain Microvessels
- (2011) Ramzi Shawahna et al. MOLECULAR PHARMACEUTICS
- Breast cancer resistance protein (BCRP/ABCG2): its role in multidrug resistance and regulation of its gene expression
- (2011) Takeo Nakanishi et al. Chinese Journal of Cancer
- ABC transporters and cytochromes P450 in the human central nervous system: influence on brain pharmacokinetics and contribution to neurodegenerative disorders
- (2010) Fabien Dutheil et al. Expert Opinion on Drug Metabolism & Toxicology
- Aryl hydrocarbon receptor-mediated up-regulation of ATP-driven xenobiotic efflux transporters at the blood-brain barrier
- (2010) Xueqian Wang et al. FASEB JOURNAL
- Activation of PKC Isoform βI at the Blood–Brain Barrier Rapidly Decreases P-Glycoprotein Activity and Enhances Drug Delivery to the Brain
- (2010) Robert R Rigor et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- 17-β-Estradiol: A Powerful Modulator of Blood–Brain Barrier BCRP Activity
- (2010) Anika MS Hartz et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Rapid Loss of Blood–Brain Barrier P-Glycoprotein Activity through Transporter Internalization Demonstrated Using a Novel in Situ Proteolysis Protection Assay
- (2010) Brian T Hawkins et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Rapid, Reversible Modulation of Blood-Brain BarrierP-Glycoprotein Transport Activity by Vascular Endothelial Growth Factor
- (2010) B. T. Hawkins et al. JOURNAL OF NEUROSCIENCE
- Estrogen Receptor Signaling through Phosphatase and Tensin Homolog/Phosphoinositide 3-Kinase/Akt/Glycogen Synthase Kinase 3 Down-Regulates Blood-Brain Barrier Breast Cancer Resistance Protein
- (2010) A. M. S. Hartz et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- BCRP at the Blood−Brain Barrier: Genomic Regulation by 17β-Estradiol
- (2010) Anne Mahringer et al. MOLECULAR PHARMACEUTICS
- Constitutive Androstane Receptor-Mediated Up-Regulation of ATP-Driven Xenobiotic Efflux Transporters at the Blood-Brain Barrier
- (2010) X. Wang et al. MOLECULAR PHARMACOLOGY
- Restoring Blood-Brain Barrier P-Glycoprotein Reduces Brain Amyloid- in a Mouse Model of Alzheimer's Disease
- (2010) A. M. S. Hartz et al. MOLECULAR PHARMACOLOGY
- Apolipoprotein E Controls ATP-Binding Cassette Transporters in the Ischemic Brain
- (2010) A. ElAli et al. Science Signaling
- Intact Lipid Rafts Regulate HIV-1 Tat Protein-Induced Activation of the Rho Signaling and Upregulation of P-Glycoprotein in Brain Endothelial Cells
- (2009) Yu Zhong et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Targeting Prostaglandin E2 EP1 Receptors Prevents Seizure-Associated P-glycoprotein Up-Regulation
- (2009) A. Pekcec et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Structure and function of the blood–brain barrier
- (2009) N. Joan Abbott et al. NEUROBIOLOGY OF DISEASE
- Prevention of seizure-induced up-regulation of endothelial P-glycoprotein by COX-2 inhibition
- (2009) Guido Zibell et al. NEUROPHARMACOLOGY
- Dexamethasone increases expression and activity of multidrug resistance transporters at the rat blood-brain barrier
- (2008) Vishal S. Narang et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- A critical overview of the influence of inflammation and infection on P-glycoprotein expression and activity in the brain
- (2008) Derek J Roberts et al. Expert Opinion on Drug Metabolism & Toxicology
- Coordinated Nuclear Receptor Regulation of the Efflux Transporter, Mrp2, and the Phase-Ii Metabolizing Enzyme, GSTπ, at the Blood—Brain Barrier
- (2008) Björn Bauer et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders
- (2008) Berislav V. Zlokovic NEURON
- Seizure-Induced Up-Regulation of P-Glycoprotein at the Blood-Brain Barrier through Glutamate and Cyclooxygenase-2 Signaling
- (2007) B. Bauer et al. MOLECULAR PHARMACOLOGY
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