Six3 regulates optic nerve development via multiple mechanisms

Identification of the optic recess region as a morphogenetic entity in the zebrafish forebrain

(2015) Pierre Affaticati et al.   Scientific Reports

Genomic code for Sox2 binding uncovers its regulatory role in Six3 activation in the forebrain

(2013) Bumwhee Lee et al.   DEVELOPMENTAL BIOLOGY

Six3 cooperates with Hedgehog signaling to specify ventral telencephalon by promoting early expression of Foxg1a and repressing Wnt signaling

(2012) D. Carlin et al.   DEVELOPMENT

Sonic hedgehog is indirectly required for intraretinal axon pathfinding by regulating chemokine expression in the optic stalk

(2012) C. S. Horndli et al.   DEVELOPMENT

Abnormal vasculature interferes with optic fissure closure in lmo2 mutant zebrafish embryos

(2012) Omri Weiss et al.   DEVELOPMENTAL BIOLOGY

A broad range of ophthalmologic anomalies is part of the holoprosencephaly spectrum

(2011) Daniel E. Pineda-Alvarez et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Sox2-mediated differential activation of Six3.2 contributes to forebrain patterning

(2011) L. Beccari et al.   DEVELOPMENT

Neuroretina specification in mouse embryos requires Six3-mediated suppression of Wnt8b in the anterior neural plate

(2010) Wei Liu et al.   JOURNAL OF CLINICAL INVESTIGATION

Development of the retina and optic pathway

(2010) Benjamin E. Reese   VISION RESEARCH

Retinal Axon Growth at the Optic Chiasm: To Cross or Not to Cross

(2008) Timothy J. Petros et al.   Annual Review of Neuroscience

Pathfinding in a large vertebrate axon tract: isotypic interactions guide retinotectal axons at multiple choice points

(2008) A. J. Pittman et al.   DEVELOPMENT

Zebrafish blowout provides genetic evidence for Patched1-mediated negative regulation of Hedgehog signaling within the proximal optic vesicle of the vertebrate eye

(2008) Jiwoon Lee et al.   DEVELOPMENTAL BIOLOGY

Haploinsufficiency of Six3 Fails to Activate Sonic hedgehog Expression in the Ventral Forebrain and Causes Holoprosencephaly

(2008) Xin Geng et al.   DEVELOPMENTAL CELL

Regulation of a remote Shh forebrain enhancer by the Six3 homeoprotein

(2008) Yongsu Jeong et al.   NATURE GENETICS

Intraretinal projection of retinal ganglion cell axons as a model system for studying axon navigation

(2007) Zheng-Zheng Bao   BRAIN RESEARCH

High-resolution in situ hybridization to whole-mount zebrafish embryos

(2007) Christine Thisse et al.   Nature Protocols