αβ T cell receptor germline CDR regions moderate contact with MHC ligands and regulate peptide cross-reactivity

T cell receptor reversed polarity recognition of a self-antigen major histocompatibility complex

(2015) Dennis X Beringer et al.   NATURE IMMUNOLOGY

Structural interplay between germline interactions and adaptive recognition determines the bandwidth of TCR-peptide-MHC cross-reactivity

(2015) Jarrett J Adams et al.   NATURE IMMUNOLOGY

T cell receptor bias for MHC: co-evolution or co-receptors?

(2014) Sneha Rangarajan et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Public T Cell Receptor  -Chains Are Not Advantaged during Positive Selection

(2014) A. L. Furmanski et al.   JOURNAL OF IMMUNOLOGY

Automated Identification of Complementarity Determining Regions (CDRs) Reveals Peculiar Characteristics of CDRs and B Cell Epitopes

(2014) Y. Ofran et al.   JOURNAL OF IMMUNOLOGY

Lck Availability during Thymic Selection Determines the Recognition Specificity of the T Cell Repertoire

(2013) François Van Laethem et al.   CELL

A Novel T Cell Subset with Trans-Rearranged V -C  TCRs Shows V  Expression Is Dispensable for Lineage Choice and MHC Restriction

(2013) S. Bowen et al.   JOURNAL OF IMMUNOLOGY

Murine thymic selection quantified using a unique method to capture deleted T cells

(2013) G. L. Stritesky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The T-cell receptor is not hardwired to engage MHC ligands

(2012) S. J. Holland et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MHC restriction is imposed on a diverse T cell receptor repertoire by CD4 and CD8 co-receptors during thymic selection

(2012) François Van Laethem et al.   TRENDS IN IMMUNOLOGY

T Cell Receptor Signaling Is Limited by Docking Geometry to Peptide-Major Histocompatibility Complex

(2011) Jarrett J. Adams et al.   IMMUNITY

αβ T Cell Receptors that Do Not Undergo Major Histocompatibility Complex-Specific Thymic Selection Possess Antibody-like Recognition Specificities

(2011) Anastasia N. Tikhonova et al.   IMMUNITY

A Single Autoimmune T Cell Receptor Recognizes More Than a Million Different Peptides

(2011) Linda Wooldridge et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Peptide-MHC heterodimers show that thymic positive selection requires a more restricted set of self-peptides than negative selection

(2010) Jeremy Juang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

T cell receptor CDR3 loops influence αβ pairing☆

(2010) Istvan Bartok et al.   MOLECULAR IMMUNOLOGY

Germline-encoded amino acids in the αβ T-cell receptor control thymic selection

(2009) James P. Scott-Browne et al.   NATURE

The molecular basis of TCR germline bias for MHC is surprisingly simple

(2009) K Christopher Garcia et al.   NATURE IMMUNOLOGY

Evolutionarily Conserved Amino Acids That Control TCR-MHC Interaction

(2008) Philippa Marrack et al.   Annual Review of Immunology

Conformational changes and flexibility in T-cell receptor recognition of peptide–MHC complexes

(2008) Kathryn M. Armstrong et al.   BIOCHEMICAL JOURNAL

TCR-MHC docking orientation: natural selection, or thymic selection?

(2008) Edward J. Collins et al.   IMMUNOLOGIC RESEARCH