BLT1 signalling protects the liver against acetaminophen hepatotoxicity by preventing excessive accumulation of hepatic neutrophils

Loss of 5-lipoxygenase activity protects mice against paracetamol-induced liver toxicity

(2015) Shiyun Pu et al.   BRITISH JOURNAL OF PHARMACOLOGY

Update on leukotriene, lipoxin and oxoeicosanoid receptors: IUPHAR Review 7

(2014) Magnus Bäck et al.   BRITISH JOURNAL OF PHARMACOLOGY

Hepatic DNA deposition drives drug-induced liver injury and inflammation in mice

(2014) Pedro Elias Marques et al.   HEPATOLOGY

Two distinct leukotriene B4 receptors, BLT1 and BLT2

(2014) T. Yokomizo   JOURNAL OF BIOCHEMISTRY

Infiltrating Monocyte-Derived Macrophages and Resident Kupffer Cells Display Different Ontogeny and Functions in Acute Liver Injury

(2014) E. Zigmond et al.   JOURNAL OF IMMUNOLOGY

VEGFR1-Positive Macrophages Facilitate Liver Repair and Sinusoidal Reconstruction after Hepatic Ischemia/Reperfusion Injury

(2014) Hirotoki Ohkubo et al.   PLoS One

Neutrophil activation during acetaminophen hepatotoxicity and repair in mice and humans

(2014) C. David Williams et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Leukotriene B4 type-1 receptor signaling promotes liver repair after hepatic ischemia/reperfusion injury through the enhancement of macrophage recruitment

(2013) Hirotoki Ohkubo et al.   FASEB JOURNAL

Endothelial membrane reorganization during leukocyte extravasation

(2012) Natalia Reglero-Real et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Chemokines and mitochondrial products activate neutrophils to amplify organ injury during mouse acute liver failure

(2012) Pedro E. Marques et al.   HEPATOLOGY

Leukotriene B4-Driven Neutrophil Recruitment to the Skin Is Essential for Allergic Skin Inflammation

(2012) Michiko K. Oyoshi et al.   IMMUNITY

Leukotriene B4 Receptor-1 Mediates Intermittent Hypoxia-induced Atherogenesis

(2011) Richard C. Li et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Deficiency of the Leukotriene B4 Receptor, BLT-1, Protects against Systemic Insulin Resistance in Diet-Induced Obesity

(2011) M. Spite et al.   JOURNAL OF IMMUNOLOGY

Acetaminophen hepatotoxicity and repair: the role of sterile inflammation and innate immunity

(2011) Hartmut Jaeschke et al.   LIVER INTERNATIONAL

The LTB4-BLT1 Axis Mediates Neutrophil Infiltration and Secondary Injury in Experimental Spinal Cord Injury

(2010) Hirokazu Saiwai et al.   AMERICAN JOURNAL OF PATHOLOGY

BLT2 Is Upregulated in Allergen-Stimulated Mast Cells and Mediates the Synthesis of Th2 Cytokines

(2010) K.-J. Cho et al.   JOURNAL OF IMMUNOLOGY

Acetaminophen-induced hepatic neutrophil accumulation and inflammatory liver injury in CD18-deficient mice

(2010) Clarence David Williams et al.   LIVER INTERNATIONAL

PGE2-regulated wnt signaling and N-acetylcysteine are synergistically hepatoprotective in zebrafish acetaminophen injury

(2010) T. E. North et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Vascular Endothelial Growth Factor Receptor-1 Signaling Promotes Liver Repair through Restoration of Liver Microvasculature after Acetaminophen Hepatotoxicity

(2010) Tetsuki Kato et al.   TOXICOLOGICAL SCIENCES

High-Mobility Group Box-1 Protein and Keratin-18, Circulating Serum Proteins Informative of Acetaminophen-Induced Necrosis and Apoptosis In Vivo

(2009) Daniel J. Antoine et al.   TOXICOLOGICAL SCIENCES

The role of damage associated molecular pattern molecules in acetaminophen-induced liver injury in mice

(2009) Brittany V. Martin-Murphy et al.   TOXICOLOGY LETTERS

Identification and characterization of infiltrating macrophages in acetaminophen-induced liver injury

(2008) Michael P. Holt et al.   JOURNAL OF LEUKOCYTE BIOLOGY