Cancer-associated fibroblasts treated with cisplatin facilitates chemoresistance of lung adenocarcinoma through IL-11/IL-11R/STAT3 signaling pathway

Cancer statistics, 2016

(2016) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Cisplatin in the modern era: The backbone of first-line chemotherapy for non-small cell lung cancer

(2016) D.A. Fennell et al.   CANCER TREATMENT REVIEWS

Targeting the interleukin-11 receptor α in metastatic prostate cancer: A first-in-man study

(2015) Renata Pasqualini et al.   CANCER

Emerging roles for IL-11 signaling in cancer development and progression: Focus on breast cancer

(2015) Cameron N. Johnstone et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Cancer-associated fibroblasts induce high mobility group box 1 and contribute to resistance to doxorubicin in breast cancer cells

(2015) Kamolporn Amornsupak et al.   BMC CANCER

Cancer Associated Fibroblast-Derived Hepatocyte Growth Factor Inhibits the Paclitaxel-Induced Apoptosis of Lung Cancer A549 Cells by Up-Regulating the PI3K/Akt and GRP78 Signaling on a Microfluidic Platform

(2015) Li Ying et al.   PLoS One

HDAC 1/4-mediated silencing of microRNA-200b promotes chemoresistance in human lung adenocarcinoma cells

(2015) Dong-Qin Chen et al.   Oncotarget

Quantitative Analysis of Histological Staining and Fluorescence Using ImageJ

(2014) Ellen C. Jensen   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

A Long Noncoding RNA Activated by TGF-β Promotes the Invasion-Metastasis Cascade in Hepatocellular Carcinoma

(2014) Ji-hang Yuan et al.   CANCER CELL

Multi-drug resistance in cancer chemotherapeutics: Mechanisms and lab approaches

(2014) Qiong Wu et al.   CANCER LETTERS

Molecular Pathways: IL11 as a Tumor-Promoting Cytokine--Translational Implications for Cancers

(2014) M. Ernst et al.   CLINICAL CANCER RESEARCH

Interleukin-11 receptor predicts post-operative clinical outcome in patients with early-stage clear-cell renal cell carcinoma

(2014) D. Pan et al.   JAPANESE JOURNAL OF CLINICAL ONCOLOGY

HMGB1-mediated autophagy promotes docetaxel resistance in human lung adenocarcinoma

(2014) Banzhou Pan et al.   Molecular Cancer

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(2014) Jin Ren et al.   MOLECULAR MEDICINE

Targeting cancer-associated fibroblasts through inhibition of protein synthesis to abrogate resistance to chemotherapies in pancreatic cancer

(2014) Camille Duluc et al.   PANCREATOLOGY

Plasma interleukin-11 (IL-11) levels have diagnostic and prognostic roles in patients with pancreatic cancer

(2014) Chuanli Ren et al.   TUMOR BIOLOGY

Cancer-associated fibroblasts induce epithelial–mesenchymal transition of breast cancer cells through paracrine TGF-β signalling

(2013) Y Yu et al.   BRITISH JOURNAL OF CANCER

Interleukin-11 Is the Dominant IL-6 Family Cytokine during Gastrointestinal Tumorigenesis and Can Be Targeted Therapeutically

(2013) Tracy L. Putoczki et al.   CANCER CELL

Autocrine production of IL-11 mediates tumorigenicity in hypoxic cancer cells

(2013) Barbara Onnis et al.   JOURNAL OF CLINICAL INVESTIGATION

Transcriptional regulation of the survivin gene

(2013) Romain Boidot et al.   MOLECULAR BIOLOGY REPORTS

A gene signature of bone metastatic colonization sensitizes for tumor-induced osteolysis and predicts survival in lung cancer

(2013) D Luis-Ravelo et al.   ONCOGENE

Cancer-associated fibroblasts and M2-polarized macrophages synergize during prostate carcinoma progression

(2013) G Comito et al.   ONCOGENE

MicroRNA-30c inhibits human breast tumour chemotherapy resistance by regulating TWF1 and IL-11

(2013) Jessica Bockhorn et al.   Nature Communications

Role of STAT3 in Cancer Metastasis and Translational Advances

(2013) Mohammad Zahid Kamran et al.   Biomed Research International

Dependency of Colorectal Cancer on a TGF-β-Driven Program in Stromal Cells for Metastasis Initiation

(2012) Alexandre Calon et al.   CANCER CELL

STC1 Expression By Cancer-Associated Fibroblasts Drives Metastasis of Colorectal Cancer

(2012) C. Pena et al.   CANCER RESEARCH

Transcriptional regulation of the interleukin-11 gene by oncogenic Ras

(2012) S. Y. Shin et al.   CARCINOGENESIS

The tumor microenvironment is a dominant force in multidrug resistance

(2012) Ana Luísa Correia et al.   DRUG RESISTANCE UPDATES

Inhibition of ZEB1 reverses EMT and chemoresistance in docetaxel-resistant human lung adenocarcinoma cell line

(2012) Jin Ren et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

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(2012) Rui Wang et al.   MOLECULAR MEDICINE

MicroRNA-200b reverses chemoresistance of docetaxel-resistant human lung adenocarcinoma cells by targeting E2F3

(2011) Bing Feng et al.   CANCER

Targeting survivin in cancer: the cell-signalling perspective

(2011) Jagat R. Kanwar et al.   DRUG DISCOVERY TODAY

Human tumors instigate granulin-expressing hematopoietic cells that promote malignancy by activating stromal fibroblasts in mice

(2011) Moshe Elkabets et al.   JOURNAL OF CLINICAL INVESTIGATION

IL11 is prognostic of survival in lung adenocarcinoma

(2011) Johannes R. Kratz et al.   JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS

On the origin of cancer-associated fibroblasts

(2010) Charlotte Anderberg et al.   CELL CYCLE

Activation of fibroblasts in cancer stroma

(2010) Kati Räsänen et al.   EXPERIMENTAL CELL RESEARCH

Chemotherapy, chemoresistance and the changing treatment landscape for NSCLC

(2010) Alex Chang   LUNG CANCER

Tumor-host histopathologic variables, stromal myofibroblasts and risk score, are significantly associated with recurrent disease in tongue cancer

(2009) Marilena Vered et al.   CANCER SCIENCE

Cancer-associated fibroblasts and tumor growth – bystanders turning into key players

(2009) Arne Östman et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

The immediate early genes, c-fos, c-jun and AP-1, are early markers of platinum analogue toxicity in human proximal tubular cell primary cultures

(2009) Richard David Wainford et al.   TOXICOLOGY IN VITRO

The tumor microenvironment and its role in promoting tumor growth

(2008) T L Whiteside   ONCOGENE