Divergent targets of glycolysis and oxidative phosphorylation result in additive effects of metformin and starvation in colon and breast cancer
出版年份 2016 全文链接
标题
Divergent targets of glycolysis and oxidative phosphorylation result in additive effects of metformin and starvation in colon and breast cancer
作者
关键词
-
出版物
Scientific Reports
Volume 6, Issue 1, Pages -
出版商
Springer Nature
发表日期
2016-01-22
DOI
10.1038/srep19569
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- The anti-proliferative effect of metformin in triple-negative MDA-MB-231 breast cancer cells is highly dependent on glucose concentration: Implications for cancer therapy and prevention
- (2014) Beshay N.M. Zordoky et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase
- (2014) Anila K. Madiraju et al. NATURE
- Direct inhibition of hexokinase activity by metformin at least partially impairs glucose metabolism and tumor growth in experimental breast cancer
- (2013) Cecilia Marini et al. CELL CYCLE
- Effects of metformin on breast cancer cell proliferation, the AMPK pathway and the cell cycle
- (2013) S. M. Hadad et al. Clinical & Translational Oncology
- Metformin Temporal and Localized Effects on Gut Glucose Metabolism Assessed Using 18F-FDG PET in Mice
- (2013) M. Massollo et al. JOURNAL OF NUCLEAR MEDICINE
- Metformin Impairs Glucose Consumption and Survival in Calu-1 Cells by Direct Inhibition of Hexokinase-II
- (2013) Barbara Salani et al. Scientific Reports
- Untuning the tumor metabolic machine: Targeting cancer metabolism: a bedside lesson
- (2012) Kıvanç Birsoy et al. NATURE MEDICINE
- Fasting Cycles Retard Growth of Tumors and Sensitize a Range of Cancer Cell Types to Chemotherapy
- (2012) C. Lee et al. Science Translational Medicine
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- Cellular and molecular mechanisms of metformin: an overview
- (2011) Benoit Viollet et al. CLINICAL SCIENCE
- Metformin suppresses glucose-6-phosphatase expression by a complex I inhibition and AMPK activation-independent mechanism
- (2009) Shinichi Ota et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Contribution of the FAD and quinone binding sites to the production of reactive oxygen species from Ascaris suum mitochondrial complex II
- (2009) Madhavi P. Paranagama et al. MITOCHONDRION
- Association of reactive oxygen species levels and radioresistance in cancer stem cells
- (2009) Maximilian Diehn et al. NATURE
- Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?
- (2009) Dunyaporn Trachootham et al. NATURE REVIEWS DRUG DISCOVERY
- Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
- (2009) M. G. Vander Heiden et al. SCIENCE
- Therapeutic metformin/AMPK activation promotes the angiogenic phenotype in the ERα negative MDA-MB-435 breast cancer model
- (2008) Kathryn N. Phoenix et al. BREAST CANCER RESEARCH AND TREATMENT
- MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification
- (2008) Jürgen Cox et al. NATURE BIOTECHNOLOGY
- Starvation-dependent differential stress resistance protects normal but not cancer cells against high-dose chemotherapy
- (2008) L. Raffaghello et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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