Article
Cell Biology
Duo-Yao Cao, Jorge F. Giani, Luciana C. Veiras, Ellen A. Bernstein, Derick Okwan-Duodu, Faizan Ahmed, Catherine Bresee, Warren G. Tourtellotte, S. Ananth Karumanchi, Kenneth E. Bernstein, Zakir Khan
Summary: ACE inhibitors can reduce the bacterial killing ability of neutrophils, leading to increased risk of infection.
SCIENCE TRANSLATIONAL MEDICINE
(2021)
Article
Chemistry, Physical
Sarra Riahi, Nizar Ben Moussa, Mohamed Lajnef, Nessrine Jebari, Ali Dabek, Radhouane Chtourou, Gregory Guisbiers, Sophie Vimont, Etienne Herth
Summary: Due to the excessive use of antibiotics in agriculture, bacteria have developed resistance, leading to the global spread of Antibiotic Resistant Bacteria and causing hundreds of thousands of deaths. This paper proposes the use of zinc oxide nanoparticles synthesized by a sol-gel technique as a potential solution against various types of bacteria, including Gram-negative, Gram-positive, and multidrug-resistant strains. The study determined the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC), and found that the zinc oxide nanoparticles were effective against several bacteria strains, including Escherichia coli, Klebsiella pneumoniae, and Staphylococcus aureus.
JOURNAL OF MOLECULAR LIQUIDS
(2023)
Article
Engineering, Biomedical
Zaoming Li, Zhiqiang Zhao, Shutong Chen, Wenjie Wu, Ying Jin, Junjie Mao, Yuqing Lin, Ying Jiang
Summary: This study focuses on chemical modifications to tailor single-atom nanoparticles, achieving targeted and light-controlled antimicrobial effects. The modified nanoparticles show superior targeted binding capabilities towards bacteria and effectively inhibit bacterial growth without noticeable toxicity to major organs. Chemical engineering plays a significant role in controlling the antibacterial properties of nanoparticles.
ADVANCED HEALTHCARE MATERIALS
(2023)
Article
Environmental Sciences
Young-Seon Ko, SungJun Park, GwangPyo Ko, Kyoungja Woo
Summary: This study investigates the antibacterial activity of silica substrate particles of different sizes and their hybrid counterparts with silver nanoparticles. The results show that particle size plays a significant role in bactericidal activity, while effective total surface area (ETSA) is considered a crucial factor influencing the antibacterial performance. Further research with various silica substrate sizes is needed to fully understand the impact of silica substrate on the antibacterial activity of immobilized silver nanoparticles.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Chemistry, Multidisciplinary
Karnini Singh, Rajesh Gujju, Sateesh Bandaru, Sunil Misra, Katragadda Suresh Babu, Nagaprasad Puvvada
Summary: This research investigates the facet-dependent activity of Ag3PO4nanostructures (APNs) containing silver in antibacterial and biofilm degradation. The cubic APNs exhibit superior antibacterial effects compared to the rhombic dodecahedral and tetrahedral-shaped APNs due to the presence of {100} facets. This study suggests that the shape of the nanostructures plays a significant role in their enzyme-mimetic activity, providing a direction for optimizing bactericidal materials.
Article
Nanoscience & Nanotechnology
Qi Feng Lim, Ray Chin Chong Yap, Choon Peng Teng, Jayven Chee Chuan Yeo, Ming Yan Tan, Jessica Pei Wen Toh, Qiang Zhu, Warintorn Thitsartarn, Chaobin He, Songlin Liu, Junhua Kong
Summary: The increasing emergence of infectious diseases like COVID-19 has created an urgent need for filtration/purification materials with multifunctional features. Polymer membranes and metal-organic frameworks (MOFs) have shown high effectiveness in air filtration and purification. In this work, an electrospray-on-electrospinning in situ process was used to integrate MOF nanoparticles into a nanofibrous membrane, resulting in advanced properties such as high mechanical strength, flexibility, breathability, particle filtration, and antimicrobial performance.
ACS APPLIED NANO MATERIALS
(2023)
Article
Microbiology
Karishma Bisht, Alex R. R. Luecke, Catherine A. A. Wakeman
Summary: Pseudomonas aeruginosa is an opportunistic pathogen frequently associated with nosocomial infections, and its ability to form robust biofilms contributes to the severity of these infections. This study demonstrates that temperature fluctuations can significantly impact the structure of P. aeruginosa biofilms, including both human body temperature and environmental temperatures. The findings highlight the importance of studying environment-specific adaptations in biofilm physiology and provide new insights into the factors that influence biofilm formation in P. aeruginosa.
FRONTIERS IN MICROBIOLOGY
(2023)
Article
Engineering, Chemical
Tharwat Shaheen, Amr Fouda, Salem S. Salem
Summary: The green biosynthesis of CuO nanoparticles using active enzymes/proteins secreted by fungi was successful in producing antibacterial textiles. Characterizations of the CuO-NPs were conducted to confirm their chemical and physical properties, which showed effective antibacterial efficacy against pathogenic bacteria.
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
(2021)
Review
Biology
Sonal Mishra, Amit Gupta, Vijay Upadhye, Suresh C. Singh, Rajeshwar P. Sinha, Donat-P. Haeder
Summary: A biofilm is an aggregate of microbial cells that forms a matrix called the extracellular polymeric substance (EPS). Infections caused by biofilm-forming microbes are associated with various animals, including insects and humans. Antibiotics and antimicrobials alone are often insufficient to completely eradicate biofilm infections due to the resistance of biofilms. Therefore, it is important for clinicians to properly treat biofilm infections with currently available antimicrobials and analyze the results. Several therapeutic strategies, including nanotechnology and quorum sensing, aim to address the resistance mechanisms of biofilms and have shown significant efficacy against bacterial biofilms.
Article
Chemistry, Multidisciplinary
Quang Thien Luong, Sun Young Kang, Dohyeon Lee, Jihyeok Song, Mohanraju Karuppannan, Yong-Hun Cho, Oh Joong Kwon
Summary: Ni@2CS/CNF catalyst synthesized by pyrolysis showed exceptional performance and long-term durability in the electro-oxidation of urea, making it a promising efficient catalyst for direct urea fuel cells.
MATERIALS CHEMISTRY FRONTIERS
(2021)
Article
Materials Science, Biomaterials
Yanwen Zhou, Haozhuo Lei, Meng Wang, Yanbin Shi, Zhaohui Wang
Summary: Novel anti-bacterial copper telluride (CuTe) nano-clusters with superior bactericidal efficiency, easy preparation, and unique mechanism were reported. The grape-like CuTe clusters showed ultra-high sterilization efficacy, especially for Gram-negative bacteria, and effectively inhibited bacterial biofilm development. Reactive oxygen species (ROS) generation and glutathione (GSH) depletion were identified as the synergized mechanisms, and electron microscopy revealed the role of the clusters as bacterial hunters. CuTe significantly reduced bacterial number in a mouse model and increased the mouse survival rate, showing promising application potential.
BIOMATERIALS SCIENCE
(2023)
Article
Chemistry, Inorganic & Nuclear
Shubhangi N. Kotkar, Subedar Prasad, Gunwant P. Gadekar, Suresh B. Rewatkar
Summary: Natural sunlight active zinc oxide nanoparticles were synthesized using a simple solution auto combustion method. The structural and optical characteristics of the nanoparticles were studied, and it was found that they exhibited excellent photodegradation activity and antimicrobial properties.
INORGANIC CHEMISTRY COMMUNICATIONS
(2022)
Article
Nanoscience & Nanotechnology
Nagarajan Padmavathy, Indranil Chakraborty, Abishek Kumar, Anindo Roy, Suryasarathi Bose, Kaushik Chatterjee
Summary: A customized polymer composite has been developed that provides electromagnetic shielding, protects medical electronics, and has antibacterial properties.
ACS APPLIED NANO MATERIALS
(2022)
Article
Multidisciplinary Sciences
Asha D. V. Bensy, G. Johnsi Christobel, Karnan Muthusamy, Ahmed Alfarhan, Perumal Anantharaman
Summary: Antimicrobial resistance is a major public health issue, and developing alternative antibiotics against drug-resistant bacteria is of utmost significance. In this study, iron nanoparticles synthesized using marine algae extract showed potent biological activities against bacteria and cancer cells.
JOURNAL OF KING SAUD UNIVERSITY SCIENCE
(2022)
Article
Polymer Science
Ranajit Barman, Debes Ray, V. K. Aswal, Suhrit Ghosh
Summary: This study investigates the importance of well-defined secondary structures of synthetic polymers in bacterial membrane perturbation. The researchers found that flexible polymers showed good antibacterial activity while rigid polymers did not. Among them, the polymer with a C6 linker exhibited the highest activity and efficacy.
Editorial Material
Environmental Sciences
Yanzheng Gao, Aki Sinkkonen, Hui Li, Patryk Oleszczuk
Article
Environmental Sciences
Hao Cheng, Chao Qin, Bing Yang, Xiaojie Hu, Michael Gatheru Waigi, Galina K. Vasilyeva, Yanzheng Gao
Summary: The interaction between phthalic acid esters (PAEs) and DNA is responsible for disrupting endocrine functions and causing teratogenic and carcinogenic effects. This study confirmed this binding interaction through a fluorescence titration quenching experiment. PAEs were found to predominantly interact with thymines in the DNA minor groove through hydrogen bonding and van der Waals forces.
ENVIRONMENT INTERNATIONAL
(2022)
Article
Engineering, Environmental
Xiaojie Hu, Michael Gatheru Waigi, Bing Yang, Yanzheng Gao
Summary: This study explored the impact of polystyrene particles with different sizes on the horizontal gene transfer of antibiotic resistance genes (ARGs) mediated by plasmids into Escherichia coli cells. The results showed that small particles had an effect on the transfer of ARGs, while large particles did not. The effects of particles on plasmid transfer varied depending on the plasmid's replication capacity. The mechanisms involved direct interaction with membrane lipids and interference with plasmid replication. This study contributes to our understanding of the environmental dissemination of ARGs in plastic contamination.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2022)
Review
Engineering, Environmental
Shunyao Li, Kai Sun, Abdul Latif, Youbin Si, Yanzheng Gao, Qingguo Huang
Summary: This review discusses the mechanism of extracellular laccase-assisted humification and its optimization strategy, highlighting the critical roles of laccase in treating micropollutants and preserving organics during livestock manure composting. The functional effects of the humification products formed by laccase-amended composting on plant growth are also discussed.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2022)
Article
Environmental Sciences
Lei Tang, Xiaochun Zhang, Zekai Li, Fredrick Owino Gudda, Michael Gatheru Waigi, Jian Wang, Hua Liu, Yanzheng Gao
Summary: This study optimized the remediation method of mixed persulfate and calcium peroxide system, which has high efficiency in remediation of soil contaminated with polycyclic aromatic hydrocarbons.
JOURNAL OF ENVIRONMENTAL MANAGEMENT
(2022)
Article
Engineering, Environmental
Kai Sun, Qingzhu Liu, Jie Liu, Shunyao Li, Xuemin Qi, Meihua Chen, Youbin Si, Yanzheng Gao
Summary: The study investigated how humic acid (HA) affects the conversion of bisphenol A (BPA) in exoenzyme-activated polyreaction. It was found that HA significantly enhanced the elimination of BPA. The presence of HA led to the formation of BPA-HA copolymers, which reduced the production of long-chain BPA self-oligomers and maintained laccase activity. Furthermore, the phytotoxicity of BPA copolymers to germinated radish seeds was lower compared to BPA self-polymers, indicating the potential for reusing these supramolecular aggregates in crop growth.
JOURNAL OF HAZARDOUS MATERIALS
(2022)
Article
Engineering, Environmental
Pengfei Cheng, Zhipeng Lin, Xuqiang Zhao, Michael Gatheru Waigi, Galina K. Vasilyeva, Yanzheng Gao
Summary: This study investigates the transformation of benzo(a)pyrene using different types of manganese oxides and their Fe(III)-modified analogues. The results show that Fe(III) modification greatly enhances the transformation capability of manganese oxides towards benzo(a)pyrene, attributed to the high Fe(III) content and abundant active free radicals. Fe(III) modification also increases the surface adsorbed water and oxygen, promoting the generation of active free radicals.
JOURNAL OF HAZARDOUS MATERIALS
(2022)
Article
Microbiology
Xian Zhou, Jian Wang, Yi Jiang, Ganghua Leng, Galina K. Vasilyeva, Michael Gatheru Waigi, Yanzheng Gao
Summary: Glomalin-related soil protein (GRSP), a natural organic compound secreted by arbuscular mycorrhizal fungi (AMF), plays an important role in the bioavailability of polycyclic aromatic hydrocarbons (PAHs) in soil. This study found that different molecular weight fractions of GRSP have varying binding capacities with PAHs, and their characteristics are crucial factors influencing their interaction.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Microbiology
Tingting Wang, Silu Sun, Yanxing Xu, Michael Gatheru Waigi, Emmanuel Stephen Odinga, Galina K. Vasilyeva, Yanzheng Gao, Xiaojie Hu
Summary: The presence of antibiotic resistance genes (ARGs) in fertilizer-amended soils poses a potential threat to human health as it can enter the food chain through a soil-vegetable system. Nitrogen, an essential nutrient in agriculture, has an influence on the distribution and accumulation of ARGs in soil and vegetables, but not on their preference for leaf or root tissues. The form of nitrogen did not play a significant role in the distribution patterns of ARGs.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Environmental Sciences
Junchao Ma, Chao Qin, Michael Gatheru Waigi, Yanzheng Gao, Xiaojie Hu, Ahmed Mosa, Wanting Ling
Summary: As a class of possible carcinogens, benzophenone-type UV filters are widely present in natural environments and organisms. This study investigated the binding of 10 typical benzophenone-type UV filters with DNA and explored their carcinogenic mechanisms. The results provide insights into the binding mode and factors influencing the binding between benzophenone-type UV filters and DNA.
Article
Environmental Sciences
Shunyao Li, Qingzhu Liu, Jie Liu, Kai Sun, Wei Yang, Youbin Si, Yucheng Li, Yanzheng Gao
Summary: This study investigated the effect mechanisms of different metal ions on BPA polyreaction using laccase from Trametes versicolor. Fe2+, Fe3+, and Mn2+ were found to strongly inhibit BPA removal, with Fe2+ being oxidized to Fe3+ and inhibiting laccase activity, and Mn2+ being oxidized to form a complex that consumed dissolved O-2 and terminated BPA removal.
Article
Agriculture, Multidisciplinary
Chao Qin, Ying-Xin Lu, Thomas Borch, Ling-Ling Yang, Yan-Wen Li, Hai-Ming Zhao, Xiaojie Hu, Yanzheng Gao, Lei Xiang, Ce-Hui Mo, Qing X. Li
Summary: This study investigates the interactions between PFAAs and DNA using various methods. The results show that PFAAs have strong binding affinities to DNA, with the major binding sites located in the grooves associated with thymine. The binding of PFAA to DNA decreases the bioavailability of PFAAs in plants.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2022)
Article
Engineering, Chemical
Xuwen Chen, Fredrick Owino Gudda, Xiaojie Hu, Michael Gatheru Waigi, Yanzheng Gao
Summary: The etched Mo2C MXene was found to be an effective catalyst for the removal of bisphenol A (BPA) by advanced oxidation using peroxymonosulfate (PMS). The catalytic activity of Mo2C MXene was attributed to the presence of Mo-deficit vacancy defects. The study also revealed the strong binding and electron transfer capabilities between Mo2C MXene and PMS, which resulted in the generation of reactive oxygen species for BPA degradation. The research provides valuable insights into the use of two-dimensional MXenes for the removal of toxic organic pollutants in water bodies.
Article
Chemistry, Multidisciplinary
Xiaojie Hu, Yanxing Xu, Si Liu, Fredrick Owino Gudda, Wanting Ling, Chao Qin, Yanzheng Gao
Summary: Graphene quantum dots (GQDs) and antibiotic resistance genes (ARGs) coexist in the environment. This study investigates the influence of GQDs on the horizontal transfer of ARGs mediated by plasmids into Escherichia coli cells. GQDs enhance ARG transfer at lower concentrations, but weaken or inhibit the transfer at higher concentrations due to aggregation and hindering of ARG entrance. This study provides understanding of the ecological risks caused by GQDs and their safe application.
Article
Engineering, Environmental
Lei Tang, Zhongkang Bao, Xuqiang Zhao, Xinbo Wang, Yanzheng Gao, Chao Lu, Wanting Ling
Summary: Wild PAH-contaminated sites face challenges in providing consistent and stable monitoring, limiting effective evaluation of the potential risks associated with the utilization of contaminated soil. This study conducted a 9-month laboratory simulation to mimic natural ecological processes and found that PAH-degrading bacteria preferred to degrade organic extracted PAH and fresh bound-PAH. The efficiency of PAH binding with humic acid was lower than that of binding with fulvic acid and humin, resulting in more persistent retention of PAH and influencing bacterial communities in shallow soils.
JOURNAL OF HAZARDOUS MATERIALS
(2023)