The parasitic worm-derived immunomodulator, ES-62 and its drug-like small molecule analogues exhibit therapeutic potential in a model of chronic asthma
出版年份 2016 全文链接
标题
The parasitic worm-derived immunomodulator, ES-62 and its drug-like small molecule analogues exhibit therapeutic potential in a model of chronic asthma
作者
关键词
-
出版物
Scientific Reports
Volume 6, Issue 1, Pages -
出版商
Springer Nature
发表日期
2016-01-14
DOI
10.1038/srep19224
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Asian Sand Dust Increases MUC8 and MUC5B Expressions via TLR4-Dependent ERK2 and p38 MAPK in Human Airway Epithelial Cells
- (2015) Yoon Seok Choi et al. American Journal of Rhinology & Allergy
- Human helminth therapy to treat inflammatory disorders- where do we stand?
- (2015) Helena Helmby BMC IMMUNOLOGY
- Ligation of TLR7 on CD19+CD1dhiB cells suppresses allergic lung inflammation via regulatory T cells
- (2015) Adnan R. Khan et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Protective effect of small molecule analogues of the Acanthocheilonema viteae secreted product ES-62 on oxazolone-induced ear inflammation
- (2015) Lamyaa Al-Riyami et al. EXPERIMENTAL PARASITOLOGY
- Asthma phenotypes and the use of biologic medications in asthma and allergic disease: The next steps toward personalized care
- (2015) Merritt L. Fajt et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- The role of the IL-33/IL-1RL1 axis in mast cell and basophil activation in allergic disorders
- (2015) Rohit Saluja et al. MOLECULAR IMMUNOLOGY
- Advances in allergen immunotherapy: Aiming for complete tolerance to allergens
- (2015) Cezmi A. Akdis et al. Science Translational Medicine
- The Parasitic Worm Product ES-62 Targets Myeloid Differentiation Factor 88-Dependent Effector Mechanisms to Suppress Antinuclear Antibody Production and Proteinuria in MRL/lprMice
- (2015) David T. Rodgers et al. Arthritis & Rheumatology
- Small molecule analogues of the immunomodulatory parasitic helminth product ES-62 have anti-allergy properties
- (2014) Justyna Rzepecka et al. INTERNATIONAL JOURNAL FOR PARASITOLOGY
- Mechanisms of allergen-specific immunotherapy: Multiple suppressor factors at work in immune tolerance to allergens
- (2014) Mübeccel Akdis et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- In utero priming by worms protects against respiratory allergies
- (2014) Hermelijn H. Smits et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Mechanisms of immune tolerance to allergens: role of IL-10 and Tregs
- (2014) Cezmi A. Akdis et al. JOURNAL OF CLINICAL INVESTIGATION
- Helminth therapy or elimination: epidemiological, immunological, and clinical considerations
- (2014) Linda J Wammes et al. LANCET INFECTIOUS DISEASES
- Cellular targets of regulatory B cell-mediated suppression
- (2014) Elizabeth C. Rosser et al. MOLECULAR IMMUNOLOGY
- Mucosal immune responses following intestinal nematode infection
- (2014) C. Zaph et al. PARASITE IMMUNOLOGY
- ES-62 Protects Against Collagen-Induced Arthritis by Resetting Interleukin-22 Toward Resolution of Inflammation in the Joints
- (2014) Miguel A. Pineda et al. Arthritis & Rheumatology
- Potential Involvement of IL-17F in Asthma
- (2014) Kyoko Ota et al. Journal of Immunology Research
- CD24hiCD27+B cells from patients with allergic asthma have impaired regulatory activity in response to lipopolysaccharide
- (2013) L. E. P. M. van der Vlugt et al. CLINICAL AND EXPERIMENTAL ALLERGY
- Signals via the Adaptor MyD88 in B Cells and DCs Make Distinct and Synergistic Contributions to Immune Activation and Tissue Damage in Lupus
- (2013) Lino L. Teichmann et al. IMMUNITY
- Protection against collagen-induced arthritis in mice afforded by the parasitic worm product, ES-62, is associated with restoration of the levels of interleukin-10-producing B cells and reduced plasma cell infiltration of the joints
- (2013) David T. Rodgers et al. IMMUNOLOGY
- Helminth therapies: Translating the unknown unknowns to known knowns
- (2013) Adnan R. Khan et al. INTERNATIONAL JOURNAL FOR PARASITOLOGY
- The helminth product, ES-62, protects against airway inflammation by resetting the Th cell phenotype
- (2013) Justyna Rzepecka et al. INTERNATIONAL JOURNAL FOR PARASITOLOGY
- Requirement for MyD88 Signaling in B Cells and Dendritic Cells for Germinal Center Anti-Nuclear Antibody Production in Lyn-Deficient Mice
- (2013) Z. Hua et al. JOURNAL OF IMMUNOLOGY
- The B cell helper side of neutrophils
- (2013) Andrea Cerutti et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Designing Anti-inflammatory Drugs from Parasitic Worms: A Synthetic Small Molecule Analogue of the Acanthocheilonema viteae Product ES-62 Prevents Development of Collagen-Induced Arthritis
- (2013) Lamyaa Al-Riyami et al. JOURNAL OF MEDICINAL CHEMISTRY
- B cells in allergic diseases: Bad or Better?
- (2012) Hermelijn H. Smits AUTOIMMUNITY
- Asthma phenotypes: the evolution from clinical to molecular approaches
- (2012) Sally E Wenzel NATURE MEDICINE
- Schistosomes Induce Regulatory Features in Human and Mouse CD1dhi B Cells: Inhibition of Allergic Inflammation by IL-10 and Regulatory T Cells
- (2012) Luciën E. P. M. van der Vlugt et al. PLoS One
- The Role of Mast Cells in the Structural Alterations of the Airways as a Potential Mechanism in the Pathogenesis of Severe Asthma
- (2011) R. J.F. Carter et al. CURRENT PHARMACEUTICAL DESIGN
- Regulatory B-cell induction by helminths: Implications for allergic disease
- (2011) Leonie Hussaarts et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Does airway smooth muscle express an inflammatory phenotype in asthma?
- (2010) Gautam Damera et al. BRITISH JOURNAL OF PHARMACOLOGY
- Experimental hookworm infection: a randomized placebo-controlled trial in asthma
- (2010) J. R. Feary et al. CLINICAL AND EXPERIMENTAL ALLERGY
- Regulatory B cells prevent and reverse allergic airway inflammation via FoxP3-positive T regulatory cells in a murine model
- (2010) Sylvie Amu et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Helminth infections associated with multiple sclerosis induce regulatory B cells
- (2008) Jorge Correale et al. ANNALS OF NEUROLOGY
Become a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get StartedAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started