Low generation anionic dendrimers modulate islet amyloid polypeptide self-assembly and inhibit pancreatic β-cell toxicity
出版年份 2016 全文链接
标题
Low generation anionic dendrimers modulate islet amyloid polypeptide self-assembly and inhibit pancreatic β-cell toxicity
作者
关键词
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出版物
RSC Advances
Volume 6, Issue 80, Pages 76360-76369
出版商
Royal Society of Chemistry (RSC)
发表日期
2016-08-05
DOI
10.1039/c6ra15373a
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Low generation polyamine dendrimers bearing flexible tetraethylene glycol as nanocarriers for plasmids and siRNA
- (2016) Rishi Sharma et al. Nanoscale
- Inhibition of hIAPP Amyloid Aggregation and Pancreatic β-Cell Toxicity by OH-Terminated PAMAM Dendrimer
- (2016) Esteban N. Gurzov et al. Small
- Molecular Tweezers Inhibit Islet Amyloid Polypeptide Assembly and Toxicity by a New Mechanism
- (2015) Dahabada H. J. Lopes et al. ACS Chemical Biology
- Delineating the Role of Helical Intermediates in Natively Unfolded Polypeptide Amyloid Assembly and Cytotoxicity
- (2015) Carole Anne De Carufel et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Glyconanosynthons as powerful scaffolds and building blocks for the rapid construction of multifaceted, dense and chiral dendrimers
- (2015) René Roy et al. CHEMICAL SOCIETY REVIEWS
- A fast track strategy toward highly functionalized dendrimers with different structural layers: an “onion peel approach”
- (2015) Rishi Sharma et al. Polymer Chemistry
- Aspirin, Diabetes, and Amyloid: Re-examination of the Inhibition of Amyloid Formation by Aspirin and Ketoprofen
- (2014) Ling-Hsien Tu et al. ACS Chemical Biology
- A highly versatile convergent/divergent “onion peel” synthetic strategy toward potent multivalent glycodendrimers
- (2014) Rishi Sharma et al. CHEMICAL COMMUNICATIONS
- Synthesis of 2,5-Diaryl-Substituted Thiophenes as Helical Mimetics: Towards the Modulation of Islet Amyloid Polypeptide (IAPP) Amyloid Fibril Formation and Cytotoxicity
- (2014) Avid Hassanpour et al. CHEMISTRY-A EUROPEAN JOURNAL
- The green tea polyphenol (−)-epigallocatechin gallate prevents the aggregation of tau protein into toxic oligomers at substoichiometric ratios
- (2014) Heike J. Wobst et al. FEBS LETTERS
- Exploiting the Therapeutic Potential of 8-β-d-Glucopyranosylgenistein: Synthesis, Antidiabetic Activity, and Molecular Interaction with Islet Amyloid Polypeptide and Amyloid β-Peptide (1–42)
- (2014) Ana R. Jesus et al. JOURNAL OF MEDICINAL CHEMISTRY
- Effect of Poly(propylene imine) Glycodendrimers on β-Amyloid Aggregation in Vitro and in APP/PS1 Transgenic Mice, as a Model of Brain Amyloid Deposition and Alzheimer’s Disease
- (2013) O. Klementieva et al. BIOMACROMOLECULES
- New insights into the roles of sulfated glycosaminoglycans in islet amyloid polypeptide amyloidogenesis and cytotoxicity
- (2013) Carole Anne De Carufel et al. BIOPOLYMERS
- Islet amyloid: From fundamental biophysics to mechanisms of cytotoxicity
- (2013) Ping Cao et al. FEBS LETTERS
- Mechanisms of islet amyloidosis toxicity in type 2 diabetes
- (2013) Andisheh Abedini et al. FEBS LETTERS
- Salvianolic acid B inhibits the amyloid formation of human islet amyloid polypeptideand protects pancreatic beta-cells against cytotoxicity
- (2013) Biao Cheng et al. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
- Dendrimers reduce toxicity of Aβ 1-28 peptide during aggregation and accelerate fibril formation
- (2012) Barbara Klajnert et al. Nanomedicine-Nanotechnology Biology and Medicine
- Tafamidis, a potent and selective transthyretin kinetic stabilizer that inhibits the amyloid cascade
- (2012) C. E. Bulawa et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mechanisms of transthyretin cardiomyocyte toxicity inhibition by resveratrol analogs
- (2011) Steve Bourgault et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Heparin Binds 8 kDa Gelsolin Cross-β-Sheet Oligomers and Accelerates Amyloidogenesis by Hastening Fibril Extension
- (2011) James P. Solomon et al. BIOCHEMISTRY
- Sulfated Glycosaminoglycans Accelerate Transthyretin Amyloidogenesis by Quaternary Structural Conversion
- (2011) Steve Bourgault et al. BIOCHEMISTRY
- Dense Shell Glycodendrimers as Potential Nontoxic Anti-amyloidogenic Agents in Alzheimer’s Disease. Amyloid–Dendrimer Aggregates Morphology and Cell Toxicity
- (2011) Oxana Klementieva et al. BIOMACROMOLECULES
- Mechanism of Amylin Fibrillization Enhancement by Heparin
- (2011) Suman Jha et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Phosphorus Dendrimers Affect Alzheimer’s (Aβ1–28) Peptide and MAP-Tau Protein Aggregation
- (2011) Tomasz Wasiak et al. MOLECULAR PHARMACEUTICS
- Dendrimers antiamyloidogenic potential in neurodegenerative diseases
- (2011) Núria Benseny-Cases et al. NEW JOURNAL OF CHEMISTRY
- Islet Amyloid Polypeptide, Islet Amyloid, and Diabetes Mellitus
- (2011) Per Westermark et al. PHYSIOLOGICAL REVIEWS
- Amyloid in the islets of Langerhans: Thoughts and some historical aspects
- (2011) Per Westermark UPSALA JOURNAL OF MEDICAL SCIENCES
- The Flavanol (−)-Epigallocatechin 3-Gallate Inhibits Amyloid Formation by Islet Amyloid Polypeptide, Disaggregates Amyloid Fibrils, and Protects Cultured Cells against IAPP-Induced Toxicity
- (2010) Fanling Meng et al. BIOCHEMISTRY
- The Sulfated Triphenyl Methane Derivative Acid Fuchsin Is a Potent Inhibitor of Amyloid Formation by Human Islet Amyloid Polypeptide and Protects against the Toxic Effects of Amyloid Formation
- (2010) Fanling Meng et al. JOURNAL OF MOLECULAR BIOLOGY
- Inhibition of Glycosaminoglycan-Mediated Amyloid Formation by Islet Amyloid Polypeptide and proIAPP Processing Intermediates
- (2010) Fanling Meng et al. JOURNAL OF MOLECULAR BIOLOGY
- EGCG remodels mature α-synuclein and amyloid-β fibrils and reduces cellular toxicity
- (2010) Jan Bieschke et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Interplay of Catalysis and Toxicity by Amyloid Intermediates on Lipid Bilayers: Insights from Type II Diabetes
- (2009) James A. Hebda et al. Annual Review of Biophysics
- Kinetic Analysis of Amyloid Formation in the Presence of Heparan Sulfate
- (2009) Neda Motamedi-Shad et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Helix Stabilization Precedes Aqueous and Bilayer-Catalyzed Fiber Formation in Islet Amyloid Polypeptide
- (2009) Jessica A. Williamson et al. JOURNAL OF MOLECULAR BIOLOGY
- A critical assessment of the role of helical intermediates in amyloid formation by natively unfolded proteins and polypeptides
- (2009) A. Abedini et al. PROTEIN ENGINEERING DESIGN & SELECTION
- Effect of Pressure on Islet Amyloid Polypeptide Aggregation: Revealing the Polymorphic Nature of the Fibrillation Process†
- (2008) Diana Radovan et al. BIOCHEMISTRY
- EGCG redirects amyloidogenic polypeptides into unstructured, off-pathway oligomers
- (2008) Dagmar E Ehrnhoefer et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
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