Article
Agronomy
Miguel Andres Lobato Ureche, Maria Micaela Perez-Rodriguez, Ramiro Ortiz, Romina Paula Monasterio, Ana Carmen Cohen
Summary: The percentage of seed germination and vigor play crucial roles in crop establishment, and in this study, it was found that inoculation with plant growth-promoting rhizobacteria significantly enhanced seedling growth and root length of pepper seeds. Changes in the profile of phenolic compounds in seeds were also observed after inoculation with PGPR, indicating potential benefits for plant defense and growth.
Article
Food Science & Technology
Silvia Tagliamonte, Raffaele Romano, Manuela Flavia Chiacchio, Alessandra Aiello, Lucia De Luca, Vincenzo Salzano, Paola Vitaglione
Summary: This study aimed to reutilize tomato pomace, a by-product of the tomato-processing industry, in the development of tomato sauce and assess its nutritional content and bioaccessibility. The innovative tomato sauce products showed higher levels of carotenoids, α-tocopherol, and total antioxidant capacity (TAC) compared to traditional sauce. Bioaccessibility of carotenoids and α-tocopherol varied among the different tomato sauce formulations, while total polyphenols content was higher in the sauce with 100% tomato pomace.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2023)
Article
Food Science & Technology
Bing Zhou, Jie Luo, Wei Quan, Aihua Lou, Qingwu Shen
Summary: The effects of liquid smoke prepared from different woods on the quality and oxidation of bacons were investigated. The study found that different liquid smoke had different phenolic compounds and antioxidant capacity. The selection of woods for antioxidant fumigants can effectively delay the oxidative spoilage of meat products.
Article
Chemistry, Multidisciplinary
Seham S. El-Hawary, Rabab Mohammed, Marwa Emad El-Din, Hossam M. Hassan, Zeinab Y. Ali, Mostafa E. Rateb, El Moataz Bellah El Naggar, Eman M. Othman, Usama Ramadan Abdelmohsen
Summary: This study examined the differences in phytochemical composition and biological properties of five strawberry hybrids, with the Suzana cultivar found to be the richest in flavonoids and total phenolics. The ethanolic extract of leaves from the Festival cultivar exhibited the highest bioactivity.
Article
Materials Science, Biomaterials
I-Ting Wu, Ying-Hung Chu, Yun-Ru Huang, Chun-Cheng Chen, Shinn-Jyh Ding
Summary: This study investigated the effect of adding different concentrations of polyphenols (GA, PG, and TA) as a liquid phase to bioactive calcium silicate cement (CSC). The results showed that the addition of polyphenols greatly enhanced the antibacterial activity of CSC against E. coli and S. aureus, but had little effect on its osteogenic activity.
JOURNAL OF MATERIALS CHEMISTRY B
(2022)
Article
Multidisciplinary Sciences
Yuna Choi, Eunyoung Park, Yohan Yoon, Jimyeong Ha
Summary: This study investigated the effects of whey bioconversion products (WBPs) produced by lactic acid bacteria on periodontal disease. The results showed that WBPs produced by LP-YK1 have stronger anti-inflammatory and antioxidant effects and can be used as a postbiotic to alleviate periodontitis.
Article
Food Science & Technology
Cristina Mihaela Luntraru, Livia Apostol, Oana Bianca Oprea, Mihaela Neagu, Adriana Florina Popescu, Justinian Andrei Tomescu, Mihaela Multescu, Iulia Elena Susman, Liviu Gaceu
Summary: The by-product from sea-buckthorn juice production is a valuable source of bioactive compounds. Ultrasonic extraction method showed better extraction of polyphenols and flavonoids, with higher antioxidant activity. The extracts contained significant amounts of minerals and the residues also contained important quantities of various elements. Ultrasonic extraction followed by concentration can achieve superior recovery of the by-product.
Article
Plant Sciences
YanLing Yin, TianHui Yang, Shuang Li, Xiaoning Li, Wei Wang, ShuGao Fan
Summary: In this study, the researchers investigated the effect of methyl jasmonate (MeJA) on salt tolerance in alfalfa plants. The results showed that exogenous MeJA could enhance salt tolerance by regulating seed germination, root growth, and antioxidant capacity. Transcriptomic analysis revealed changes in gene expression related to secondary metabolism, redox regulation, cell cycle, transcription factors, and other signal transductions. Additionally, the researchers identified hub genes that were highly correlated with antioxidant enzymes activity and ion content.
FRONTIERS IN PLANT SCIENCE
(2023)
Article
Plant Sciences
Xinyue Wang, Feiyang Chang, Qinglong Dong, Peng Jia, Haoan Luan, Xiaoxiang Wang, Jiaan Zhang, Xu Yuan, Xuemei Zhang, Sumiao Yang, Guohui Qi, Suping Guo
Summary: This study investigated the effect mechanism of exogenous selenium fertilizer on the browning of fresh-cut apples. It was found that selenium-rich apples exhibited a stronger ability to resist browning. Exogenous selenium can alleviate fresh-cut apples browning by improving antioxidant capacity and reducing polyphenol oxidase activity.
JOURNAL OF PLANT PHYSIOLOGY
(2023)
Article
Chemistry, Applied
Mariana de Morais Sousa, Rosalia Maria Lima, Alessandro de Lima, Antonielly Campinho Reis, Ana Amelia de Carvalho Melo Cavalcante, Jose Augusto Gasparotto Gasparotto Sattler, Ligia Bicudo de Almeida-Muradian, Jose de Sousa Lima Neto, Regilda Saraiva dos Reis Moreira-Araujo, Nadir do Nascimento Nogueira
Summary: Jambolan pulp is rich in antioxidant polyphenols, and the study investigated changes in polyphenols and antioxidant capacity during in vitro digestion and chemical extraction. The research found that the digestion process enhances the release of bio-polyphenols with preventive, scavenger, and reparative antioxidant action, which modulate the antioxidant enzymes of S. cerevisiae.
Article
Food Science & Technology
Huifen Zhang, Jing Pu, Yan Tang, Miao Wang, Kun Tian, Yongqing Wang, Xian Luo, Qunxian Deng
Summary: Plums have high levels of phenolic compounds and strong antioxidant activity. This study investigated the changes in appearance, internal quality, phenolic compounds, and antioxidant activities during fruit development of two main plum cultivars in Sichuan. The results showed that soluble solid and sugar contents were highest at maturity. Phenolic contents decreased as the fruits matured, while anthocyanin content increased in one of the cultivars. The peel had higher phenol, phenolic components, and antioxidant capacity than the pulp. Certain genes were found to be associated with the accumulation of phenolic substances. The study provides a theoretical basis for the development of bioactive substances in local plum cultivars.
Article
Biochemistry & Molecular Biology
Tianjun Zhang, Dongjie Huang, Xianyu Liu, Fabin Chen, Yiyan Liu, Yang Jiang, Dapeng Li
Summary: In order to improve the economic benefits of the coffee industry chain, we conducted research on the processing by-products, specifically the coffee cherry peel polysaccharide (CCP). The CCP exhibited high antioxidant capacity and emulsification performance, outperforming the commercial citrus polysaccharide (APC). Additionally, we discovered that CCP could form a solid-liquid gel with high plasticity at low oil phase fraction. This research highlights the potential of coffee cherry peel as a natural emulsifier alternative in the food industry.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Review
Chemistry, Multidisciplinary
Liyun Wang, Bihui Zhu, Yuting Deng, Tiantian Li, Qinyu Tian, Zhiguo Yuan, Lang Ma, Chong Cheng, Quanyi Guo, Li Qiu
Summary: ROS significantly affect human physiological activities and lead to chronic diseases in inflammatory tissues. Many antioxidant molecules and enzymes have limitations, but biocatalytic or antioxidant nanostructures show promising ROS scavenging capabilities. This review summarizes recent advancements in engineering these nanostructures for ROS scavenging, including principles, methods, efficiencies, and applications.
ADVANCED FUNCTIONAL MATERIALS
(2021)
Article
Food Science & Technology
Xuejiao Qie, Zhucheng Yin, Zhen He, Chaoyi Xue, Zhaojun Wang, Qiuming Chen, Maomao Zeng, Jie Chen, Zhiyong He
Summary: The study investigated the effect of thermally-induced interactions between beta-casein (beta-CN) and phlorizin (Phl) on the antioxidant activity and bioavailability of Phl. The results showed that Phl and beta-CN interacted mainly through hydrogen bonds and Van der Waals forces. The thermal treatment increased the ABTS values of the beta-CN-Phl complex but had little effect on its FRAP. However, the thermal treatment at 121 degrees C decreased the bioavailability of Phl and weakened the binding strength of Phl-beta-CN.
Article
Environmental Sciences
Jose Seco, Rosa Freitas, Jose C. Xavier, Paco Bustamante, Joao P. Coelho, Francesca Coppola, Ryan A. Saunders, Angela Almeida, Sophie Fielding, Miguel A. Pardal, Gabriele Stowasser, Giulia Pompeo, Geraint A. Tarling, Andrew S. Brierley, Eduarda Pereira
Summary: This study examined the indicators of oxidative stress and metabolic capacity in two species in the Southern Ocean, Antarctic krill and myctophid fish, as well as analyzed mercury concentrations and their potential impacts. The results showed that Antarctic krill had higher metabolic activity but lower antioxidant enzyme activity compared to myctophid species. There was no relationship found between mercury concentrations and organisms' defense mechanisms, indicating that the levels were not high enough to adversely affect their biochemical processes.
MARINE POLLUTION BULLETIN
(2021)
Article
Biochemistry & Molecular Biology
Rita Nasti, Ivan Bassanini, Erica Elisa Ferrandi, Federica Linguardo, Susanna Bertuletti, Marta Vanoni, Sergio Riva, Luisella Verotta, Daniela Monti
Summary: This study successfully recovered active components from fermented ginger waste biomass and achieved enantioenriched sec-alcohol derivatives via a sustainable biocatalytic path.
Review
Food Science & Technology
Hiba N. Rajha, Armelle Paule, Gerard Aragones, Mariana Barbosa, Carla Caddeo, Esperance Debs, Rada Dinkova, Gunter P. Eckert, Ariel Fontana, Prisca Gebrayel, Richard G. Maroun, Alessandra Napolitano, Lucia Panzella, Giulio Maria Pasinetti, Jan F. Stevens, Andreas Schieber, Marvin Edeas
Summary: Polyphenols have attracted researchers from various disciplines due to their diverse biological activities. The latest scientific research has focused on polyphenol interactions with the microbiome and mitochondria, as well as their potential applications in cosmetics, dietary supplements, and functional foods. Polyphenols may play a key role in disease prevention and have promising prospects in future food and nutrition.
MOLECULAR NUTRITION & FOOD RESEARCH
(2022)
Review
Biochemistry & Molecular Biology
Bruno Burlando, Laura Cornara, Raffaella Boggia
Summary: This review focuses on three species of berries, including the high-latitude cloudberry, arctic bramble, and high-altitude yellow raspberry. These berries are rich in ellagitannins (ETs) and other phenolic compounds, which make them potential nutraceuticals with antioxidant and bioactive properties. The health benefits of ETs include anti-inflammatory, antiviral, anti-bacterial, and anticancer actions. The review covers ethnobotanical, pharmaceutical, medicinal, and nutritional knowledge about these berries, revealing a wide range of potential uses in health care.
CURRENT MEDICINAL CHEMISTRY
(2023)
Article
Chemistry, Physical
Vincent Ball, Maria Laura Alfieri, Kevin Ziegler, Youri Arntz, Marco d'Ischia
Summary: The deposition efficiency and electrochemical properties of coatings obtained from different benzenediols were compared. Resorcinol showed higher deposition efficiency compared to catechol, while hydroquinone did not form detectable coating. Catechol and hydroquinone exhibited reversible electrochemical properties, while resorcinol displayed an irreversible process. The results provide insights for future studies on coating design and tailoring.
SURFACES AND INTERFACES
(2022)
Review
Biochemistry & Molecular Biology
Gregorio Bonsignore, Simona Martinotti, Elia Ranzato
Summary: The unfolded protein response (UPR) is an adaptive response triggered by endoplasmic reticulum (ER) stress for re-establishing protein homeostasis. Specific ER proteins mediate UPR activation by dissociating from chaperone Glucose-Regulated Protein 78 (GRP78). UPR can decrease ER stress, produce an ER adaptive response, block UPR if ER homeostasis is restored, or regulate apoptosis. This review focuses on molecules that target ER stress and demonstrate how UPR could be a new target in cancer treatment.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Carlotta Bollati, Stefania Marzorati, Lorenzo Cecchi, Martina Bartolomei, Jianqiang Li, Maria Bellumori, Lorenza d'Adduzio, Luisella Verotta, Laura Piazza, Anna Arnoldi, Nadia Mulinacci, Carmen Lammi
Summary: To improve the management of the production chain of PGI Mantua pears, fruits with diseases or defects were used to produce dried rounds of pears, extending the remaining life. The secondary and residual by-products of the pears were then utilized to extract valuable phytocompounds using traditional and green extraction methods. The extracted compounds showed antioxidant activity, suggesting their potential use in dietary supplements and functional foods.
Article
Biochemistry & Molecular Biology
Sara Viggiano, Lucia Panzella, Maria Reichenbach, Joachim Hans, Alessandra Napolitano
Summary: Immediate pigment darkening, the rapid onset of melanin pigmentation resulting from oxidation, can lead to irregular pigmentation and dark spots. Phenolic cosmetic ingredients (CIs) such as paradol-6 and phenylethyl resorcinol can decrease the oxidation and melanin formation of 5,6-dihydroxyindole (DHI) and 5,6-dihydroxyindole-2-carboxylic acid (DHICA). CIs also show photoprotective effects in model systems, reducing peroxidation and generation of reactive oxygen species. These findings have potential implications for the development of skincare formulations to improve skin spots and counteract aging processes associated with sun exposure.
Article
Biochemistry & Molecular Biology
Rita Argenziano, Maria Laura Alfieri, Noemi Gallucci, Gerardino D'Errico, Lucia Panzella, Alessandra Napolitano
Summary: The search for new synthetic melanin-related pigments with antioxidant and photoprotective properties is important for dermo-cosmetic purposes. In this study, a melanin derived from 5,6-dihydroxyindole-2-carboxylic acid (DHICA) was synthesized and found to have similar structural properties to DHICA melanin. The synthesized pigment demonstrated stronger UV-visible absorption and improved solubility compared to DHICA melanin. Furthermore, the pigment exhibited marked antioxidant properties and enhanced inhibitory action against lipid peroxidation. These findings suggest that the melanin derived from DHICA has potential as a functional ingredient in dermo-cosmetic formulations.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Antonella Smeriglio, Susanna Alloisio, Raffaella Barbieri, Mariarosaria Ingegneri, Paola Malaspina, Bruno Burlando, Laura Cornara, Domenico Trombetta
Summary: Citrus lumia Risso and Poit. 'Pyriformis' are horticultural varieties of Citrus lumia Risso. The fruit is very fragrant and pear-shaped, with a bitter juice, a floral flavor, and a very thick rind. The essential oil extracted from the rind has shown interesting antioxidant, anti-inflammatory, and neuroinhibitory effects, as well as acetylcholinesterase inhibitory activity.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Chemistry, Multidisciplinary
Ada Truscello, Sonia Colletti, Cristian Gambarotti, Marco A. Ortenzi, Stefano Gazzotti, Maurizio S. Galimberti
Summary: This study reports the synthesis of biosourced mellophanic dianhydride (MEDA) from agricultural waste and its use as a chain extender for mechanically recycled PET (R-PET) as a sustainable alternative to oil-based pyromellitic dianhydride (PMDA). The rheological tests showed similar results between R-PET extruded with MEDA and PMDA, and DMTA analysis indicated that R-PET containing MEDA had a 20% higher Young's modulus compared to pristine R-PET in the temperature range commonly used for blow molding bottles. The advantage of MEDA lies in its sustainable production using agricultural waste, while PMDA is derived from oil-based chemistry.
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2023)
Article
Biochemistry & Molecular Biology
Carmela Spagnuolo, Federica Moccia, Idolo Tedesco, Eva Adabbo, Lucia Panzella, Gian Luigi Russo, Alessandra Napolitano
Summary: The extract obtained from the waste of fermented strawberry distillate production exhibited high antioxidant and antiproliferative properties, mainly attributed to the presence of ellagic acid and p-coumaric acid. It showed strong antiproliferative effects on human cancer cell lines, especially on HL-60 cells, through rapid apoptosis induction. The extract also exhibited antioxidant activity and modulation of cellular oxidative stress and signaling pathways.
Article
Biochemistry & Molecular Biology
Viviana Mucci, Ilaria Demori, Cherylea J. Browne, Choi Deblieck, Bruno Burlando
Summary: Fibromyalgia (FM) is a chronic pain disorder with unclear pathophysiological mechanisms, which leads to challenges in patient management. It presents with a broad range of symptoms and has a considerable female prevalence. Symptoms of FM can worsen during pregnancy, particularly during the third trimester and after childbirth. This perspective paper proposes the involvement of neuro-endocrine interactions in FM pathogenesis during pregnancy and suggests the potential use of transcranial direct current stimulation (tDCS) as a non-invasive treatment with sex-specific effects on FM patients.
Article
Chemistry, Applied
Ghislain Fotie, Stefano Gazzotti, Marco Aldo Ortenzi, Sara Limbo, Luciano Piergiovanni
Summary: This article compares the gas barrier performance of plastic films coated with cellulose nanocrystals (CNCs) and microfibrillated cellulose (MFC) obtained from cotton linters. The CNCs were chemically isolated using ammonium persulfate (APS) hydrolysis, while the MFC was obtained mechanically either with or without APS-assisted pre-treatment. Mechanical tests and various characterization techniques were performed on the samples. Coated PET films were then evaluated for water contact angle, transparency, opacity, water vapor transmission rate, and oxygen transmission rate. The findings show that MFCaps-based coated films have better oxygen barrier properties at higher relative humidity and higher residue levels during degradation compared to CNCs.
CARBOHYDRATE POLYMER TECHNOLOGIES AND APPLICATIONS
(2023)
Article
Biochemistry & Molecular Biology
Antonella Smeriglio, Joseph Lionti, Mariarosaria Ingegneri, Bruno Burlando, Laura Cornara, Federica Grillo, Luca Mastracci, Domenico Trombetta
Summary: The study investigated the use of the diatom Phaeodactylum tricornutum Bohlin (Phaeodactylaceae) as a functional ingredient for nutraceutical and cosmeceutical applications. It was found that the extract from this diatom, which contains high levels of neutral lipids and xanthophylls, exhibited excellent antioxidant activity and photostability against UVA and UVB rays. In addition, it was also shown to effectively reduce oxidative and inflammatory stress markers induced by solar radiation, making it a potentially safe and effective ingredient in broad-spectrum sunscreens.
Review
Cell Biology
Irene Fiorilla, Simona Martinotti, Alberto Maria Todesco, Gregorio Bonsignore, Maria Cavaletto, Mauro Patrone, Elia Ranzato, Valentina Audrito
Summary: Malignant pleural mesothelioma (MPM) is a lethal and rare cancer with increasing incidence worldwide. Asbestos exposure causes MPM through mechanisms including chronic inflammation, oxidative stress, and aberrant signaling. The tumor microenvironment characteristics, such as chronic inflammation, hypoxia, and metabolic changes, support tumor aggressiveness and modulate immune responses. Understanding these interactions provides potential therapeutic targets in MPM.
