期刊
RSC ADVANCES
卷 6, 期 1, 页码 109-118出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5ra20954d
关键词
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资金
- Council of Scientific and Industrial Research (CSIR), New Delhi
- CSIR network [BSC0102]
A facile regioselective metal-free direct alpha-arylation of coumarins and 2-pyridones is achieved by the reaction of coumarins and 2-pyridones with phenylhydrazine in good yields. The reaction proceeds at room temperature under mild conditions using inexpensive reagents and without the need for step intensive activating groups. The methodology is operationally simple, practically viable and also allows the coupling of similar nitrogen heterocycle aza-coumarins without prerequisite N-protection.
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