Article
Chemistry, Physical
Can Cui, Qi Ye, Cheng Zeng, Shuhao Wang, Xiaowei Xu, Tianyou Zhai, Huiqiao Li
Summary: Constructing garnet solid electrolyte with a lithiophilic graphite interface via one-step integrated spark plasma sintering method can reduce interfacial resistance and improve homogenization of lithium-ion flux, thereby enhancing the performance of solid-state batteries.
ENERGY STORAGE MATERIALS
(2022)
Article
Chemistry, Multidisciplinary
J. Li, P. Liu
Summary: In this study, Cu(II)-complexed CDs (Cu(II)-CDs NPs) were designed for tumor intracellular glutathione-activated cuprous ion-mediated therapy and real-time imaging. The Cu(II)-CDs NPs could release CDs and Cu(I) ions in the intracellular environment, showing strong tumor specificity.
MATERIALS TODAY CHEMISTRY
(2022)
Article
Environmental Sciences
Guobin Song, Liya Tong, Shuhua Chen, Jing Zhang, Yi Zhang, Haonan Wang, Yawei Shi, Ya Sun, Guanghui Ding
Summary: In this study, amino functionalized magnetic multi-walled carbon nanotubes (MMWCNT-NH2) were prepared via a facile one-pot solvothermal method, and their sorptive removal efficiency of the anionic dye Congo red (CR) from water was investigated. The composite with triethylenetetramine showed higher removal efficiency due to its higher content of amino groups. Characterization analyses confirmed its excellent magnetic separation property and successful introduction of amino groups on MMWCNTs. The adsorption process followed the pseudo-second-order kinetic model and a three-stage diffusion mechanism was observed. The adsorption performance of MMWCNT-NH2-3 showed significant improvement after amino functionalization, with a maximum adsorption capacity of 322.7 mg/g. Selective adsorption of anionic dye was achieved due to electrostatic attraction and electron donor-acceptor interaction. The prepared MMWCNT-NH2-3 exhibited excellent reusability performance and could be a promising adsorbent for the removal of anionic dye from wastewater.
WATER AIR AND SOIL POLLUTION
(2022)
Article
Chemistry, Physical
Jiaqi Qiu, Jinjin Huang, Xiaokang Zhu, Yuting Min, Dongming Qi, Tao Chen
Summary: The study demonstrates the fabrication of highly efficient and recyclable micellar nanoreactors via self-assembly of catalyst-containing amphiphilic copolymers in water, using a one-step strategy of polymerization-induced self-assembly. The nanoreactors showed high catalytic activity and easy recyclability, making them promising for green organic transformations.
MOLECULAR CATALYSIS
(2022)
Article
Polymer Science
Yuanyuan Xue, Anna Marie LaChance, Jingjing Liu, Maria Farooqui, Marina D. Dabaghian, Fuchuan Ding, Luyi Sun
Summary: Polymer nanocomposites containing alpha-Zirconium phosphate (Zr(HPO4)2) (ZrP) nanosheets were prepared and investigated for their properties. The ZrP nanosheets were well distributed and oriented in a polyvinyl alcohol (PVA) matrix. The coated PLA films showed high clarity even with a high percentage of ZrP nanosheets. The resulting nanocomposites exhibited improved barrier properties and mechanical strength compared to neat PVA.
Article
Chemistry, Applied
Chun Wang, Yangjuan An, Zhi Li, Qianqian Wang, Weihua Liu, Lin Hao, Zhi Wang, Qiuhua Wu
Summary: Three hydroxyl-functionalized hypercrosslinked polymers were synthesized by Friedel-Crafts reaction. Among them, HCP-HQ exhibited the largest surface area and highest adsorption capacity for chlorophenols. A magnetic solid-phase extraction method with M-HCP-HQ as adsorbent was developed for the simultaneous extraction of chlorophenols from water and honey samples, providing a reliable and sensitive tool for detection.
Article
Chemistry, Physical
Swati Bishnoi, Bhawani P. S. Panwar, Sudip K. Pattanayek
Summary: There is a growing demand for advanced coatings with remarkable physical properties such as high transparency, water resistance, spectrum conversion, and dust repellence. This study used silicon quantum dots and a silane-based material composite to build thin films with a unique combination of hydrophobicity, self-cleaning, and the ability to convert UV to visible spectrum. The incorporation of silica-silane based layer further enhanced water resistance and dust resistance. The novel layered structure has potential in outer coating applications for solar photovoltaic systems and various outdoor glasses.
SURFACES AND INTERFACES
(2023)
Article
Materials Science, Multidisciplinary
Hong-Li Ye, Chao Jia, Xi-Wen He, Wen-You Li, Yu-Kui Zhang
Summary: Functionalized water-soluble silicon nanoparticles were successfully synthesized and applied in biomedical imaging. The properties of the functionalized SiNPs, including improved fluorescence intensity, photoluminescence quantum yield, fluorescence lifetimes, photo-stability, and biocompatibility, were significantly enhanced. The longitudinal relaxation of Gd-SiNPs was found to be higher than that of the commercial contrast agent Gd-DTPA. The charming Gd-SiNPs were successfully used as a biologic probe in fluorescence and magnetic resonance dual-mode imaging in vivo and in vitro.
JOURNAL OF MATERIALS SCIENCE
(2022)
Article
Chemistry, Applied
Xinyi Wang, Bin Zhou, Di Wu, Xiaojuan Chen, Bin Li, Ling Wang, Hongshan Liang
Summary: In this study, a stabilization system was developed for NOB nanocrystals through an anti-solvent method combined with ultrasonic treatment. The introduction of metal-phenolic networks enhanced the stability of the nanocrystals, which showed promising results in terms of stability, acid resistance, and release properties. This work provides a potential solution for improving the storage and delivery of hydrophobic crystalline bioactive components.
Article
Biophysics
Ying Mao, Robert Guidoin, Gaetan Brochu, Yan Li, Ze Zhang, Fujun Wang, Lu Wang
Summary: Electrospun phospholipid-functionalized NFMs serve as potential anti-adhesion barriers with enhanced wettability and anti-adhesion efficiency, showing long-lasting anti-adhesion capability against fibroblasts and superior anti-inflammatory effects on macrophages.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2021)
Article
Materials Science, Ceramics
Chen Wang, Zhifeng Shen, Pengfei Hu, Tao Wang, Xing Zhang, Lidong Liang, Jianguang Bai, Liewei Qiu, Xiaojuan Lai, Xiaowu Yang, Kang Zhang
Summary: Borax-PVA hydrogels with excellent mechanical properties were prepared by physically mixing PVA and borax, forming a three-dimensional structure with boric ester bonds. The hydrogels exhibited reversible gel-sol conversion and self-healing properties, with the best mechanical performance observed at a borax mass fraction of 5%.
JOURNAL OF SOL-GEL SCIENCE AND TECHNOLOGY
(2022)
Article
Engineering, Chemical
Tong Yu, Xin Wang, Zhiyu Liu, Zhongyan Chen, Zhuan Hong, Mingen Zhang, Quanxing Zheng, Wenyao Shao, Quanling Xie
Summary: By introducing amino acid-functionalized graphene quantum dots, the desalination performance and self-cleaning performance of nanofiltration membranes can be improved without sacrificing water flux and salt rejection. AA-fGQDs with polar amino acids and low bandgap energies demonstrate better performance.
JOURNAL OF MEMBRANE SCIENCE
(2022)
Article
Chemistry, Physical
Ruihan Liu
Summary: A facile approach was established to synthesize magneto-fluorescent carbon dots with mixed phase of Fe3O4 and FeO, exhibiting excitation-independent fluorescence behavior for potential multimodal cellular imaging applications.
JOURNAL OF ALLOYS AND COMPOUNDS
(2021)
Article
Spectroscopy
Ying Yang, Chaofeng Wang, Qin Shu, Na Xu, Shuangqing Qi, Shujuan Zhuo, Changqing Zhu, Jinyan Du
Summary: Cu-doped carbon dots were synthesized via a one-pot hydrothermal method, showing excellent performance in detecting PPi and pH values. The results indicate promising applications of Cu-CDs in biosensing.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Chemistry, Physical
Yining Wu, Lisha Tang, Mengjiao Cao, Li Li, Kai Liu, Demin Kong, Qingshan Zhao, Xu Jin, He Liu, Caili Dai
Summary: In this study, amino-modified carbon dots (am-CDs) were synthesized and used as a nanofluid for enhanced oil recovery. The am-CDs showed remarkable oil recovery efficiency, outperforming traditional methods. This study provides a new strategy for developing efficient carbon dots-based nanofluids for enhanced oil recovery.
Article
Chemistry, Analytical
Bingzhi Li, Bin Zhou, Yue Chen, Xing Zhang, He Huang
Summary: In this study, a new strategy was proposed to sensitively detect transcription factors using T4 DNA ligase protection assay and rolling circle amplification. By preventing the ligation reaction through the binding of T4 DNA ligase to the nick region of dsDNA, the undesired dissociation of TF-DNA complexes was effectively avoided, improving the accuracy of the assay. Through sequence engineering, multiple transcription factors can be detected at low picomolar levels.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Chemistry, Analytical
Muhammad Sohail, Bin Xie, Bingzhi Li, He Huang
Summary: The determination of antioxidant activity plays a crucial role in health sciences and food technology as it is directly related to oxidative stress and various diseases. In this study, a Zn-CDs-based bioanalytical probe was developed for the estimation of antioxidant activity index (AAI), providing a more robust and accurate method compared to traditional techniques.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Fisheries
Ximei Nie, Yuqi Zhao, Hao Xu, Zhengxiao Han, Xing Zhang, Bingzhi Li, Xin Huang, Jiachun Ge, Qian Ren
Summary: In this study, we investigated the effects of HPND on the innate immune regulation in Chinese mitten crab and found that the Toll-crustin signaling pathway is activated in diseased crabs. Our findings provide new insights for HPND research.
Review
Biochemistry & Molecular Biology
Furong Zhao, Siying Xie, Bingzhi Li, Xing Zhang
Summary: This review discusses the roles of carbohydrates and glycoconjugates in organisms and the applications of FNAs-based biosensors in detecting disease-related substances. By summarizing construction strategies and biosensing applications, challenges and development opportunities in this area are highlighted.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Review
Chemistry, Analytical
Muhammad Sohail, Lingyun Qin, Shuxian Li, Yue Chen, Muhammad Haidar Zaman, Xing Zhang, Bingzhi Li, He Huang
Summary: The CRISPR/Cas machinery has revolutionized the analytical platform for precise detection. This review highlights the role of reporter engineering in improving the CRISPR/Cas-based detection platform, focusing on reporter elements, nucleic acid sequences, and transducers for multiplexing and target differentiation. The review discusses the significance of reporters, their impact on signal generation, working principles, limitations of CRISPR technology, and future investigations.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2022)
Article
Gastroenterology & Hepatology
Meng-huan Wang, Bing-zhi Li, Yue Chen, Jie Wang
Summary: This study evaluated the expression levels of TEADs in gastric cancer samples and observed the clinical outcomes of patients with high TEADs expression. Further analysis suggested that TEADs may serve as prognostic biomarkers or therapeutic targets for gastric cancer.
BMC GASTROENTEROLOGY
(2022)
Article
Chemistry, Analytical
Bingzhi Li, Qiusu Wang, Muhammad Sohail, Xing Zhang, Huan He, Lei Lin
Summary: The blooming of cyanobacteria in aquatic environments can produce various cyanotoxins polluting soil and water, raising major concerns over environmental and human health issues. Microcystins (MCs) are one of the most toxic cyanotoxins, and the monitoring of MCs is critical for environmental protection and public health. Bio-inspired sensors, also known as biosensors, have become an emerging tool for the detection of MCs.
MICROCHEMICAL JOURNAL
(2023)
Article
Chemistry, Analytical
Zhirun Ji, Zhaoyang Shang, Muhammad Sohail, Pei Wang, Bingzhi Li, Xing Zhang, Guoxiang Chen
Summary: In this study, a fluorometric biosensor based on the protamine-mediated regulation of CRISPR/Cas12a collateral cleavage was developed for the sensitive detection of protamine. The biosensor transduces the information of protamine concentration into DNA information and senses it in a signal turn-off manner.
SENSORS AND ACTUATORS B-CHEMICAL
(2023)
Article
Chemistry, Analytical
Pei Wang, Xue Zhang, Hui Shen, Qunwei Lu, Bingzhi Li, Xin Liu, Song Gao
Summary: This study developed a point-of-care testing (POCT)-friendly detection method for Enterocytozoon hepatopenaei (EHP) infection by combining recombinase polymerase amplification (RPA) with the CRISPR-Cas12a system. The method showed improved accuracy and reliability by utilizing the robust amplification capacity of RPA and high specificity of CRISPR. By carefully designing crRNA and optimizing the reaction, the one-pot procedure was achieved, solving the compatibility issues between RPA and Cas12a cleavage. The method demonstrated high specificity and sensitivity, making it suitable for POCT environment and having great application value in preventing EHP infection in the shrimp farming industry.
SENSORS AND ACTUATORS B-CHEMICAL
(2023)
Article
Nanoscience & Nanotechnology
Jie Zheng, Han Xu, Bingzhi Li, Muhammad Sohail, Jingjing Bi, Fuming Zhang, Robert J. Linhardt, He Huang, Xing Zhang
Summary: Based on the Modular-Enzymes Assembly by Spatial Segregation (MASS) strategy, a universal immobilization platform was developed to assemble multiple glycoenzymes in compartmentalized MOF particles, reducing interference and cross-inhibitions. Different glycans, including glycosyl donor, disaccharides, oligosaccharides, and polysaccharides with cofactor regeneration, were efficiently prepared. This robust multienzyme immobilization platform has industrial potential for enzymatic synthesis of more complex glycans.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Biochemical Research Methods
Xiaochen Ma, Tiying Suo, Furong Zhao, Zhaoyang Shang, Yue Chen, Pei Wang, Bingzhi Li
Summary: This study developed a fluorometric aptasensor for the detection of cadmium ions (Cd(II)) by integrating strand displacement amplification (SDA) and CRISPR/Cas12a technologies. In the absence of Cd(II), the aptamer initiates SDA and activates Cas12a, resulting in a significant increase in fluorescence output. Conversely, the presence of Cd(II) reduces the efficiency of SDA, leading to a notable decrease in fluorescence output. The proposed method enables selective detection of Cd(II) at concentrations of 60 pM and has been validated in real water and rice samples. It holds great promise as a signal-amplified and precise detection platform for Cd(II), potentially transforming current hazard detection practices in food samples.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Bin Zhou, Runlin Yang, Muhammad Sohail, Xiaoxue Kong, Xing Zhang, Ninghua Fu, Bingzhi Li
Summary: CRISPR is revolutionizing biosensing technology with its programmability, sensitivity, and specificity. While most CRISPR-based biosensors are developed using Cas12 and Cas13, the biosensing potential of the newly discovered Cas14 is not yet fully understood. This study introduces HARRY, a fluorometric biosensor that utilizes the specificity of Cas14a for versatile aptasensing. HARRY shows improved sensitivity and versatility compared to Cas12a-based aptasensors, detecting various targets at low-nanomolar levels. The study suggests that the detection limit of HARRY is correlated to the binding affinities of aptamers. These findings unlock the potential of Cas14a in CRISPR-based biosensing and inspire further development in this field.
Article
Chemistry, Analytical
Jianwen Fei, Wei Yang, Yin Dai, Wei Xu, Huizhu Fan, Yani Zheng, Jun Zhang, Wanying Zhu, Junli Hong, Xuemin Zhou
Summary: A novel magnetic nanozyme Fe3O4@ MXene-Au nanocomposite with higher peroxidase-like activity was developed. It exhibited outstanding magnetic properties, allowing for easy separation and great recyclability. A highly selective colorimetric biosensor for glucose detection was created using Fe3O4@ MXene-Au nanocomposites and glucose oxidase (Glu Ox).
Review
Environmental Sciences
Muhammad Sohail, Zunaira Urooj, Sobia Noreen, Mirza Muhammad Faran Ashraf Baig, Xing Zhang, Bingzhi Li
Summary: Micro-and nanoplastics (M/NPs) are emerging pollutants released into the food, beverages, and environment from plastic products. Detection of M/NPs in food and beverages is crucial for preventing their harmful effects. However, current analytical strategies have limitations and detecting M/NPs accurately is challenging due to their varying content and contamination routes.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Chemistry, Analytical
Furong Zhao, Pei Wang, Haoxuan Wang, Sirui Liu, Muhammad Sohail, Xing Zhang, Bingzhi Li, He Huang
Summary: The spread of monkeypox virus (MPXV) from Central and West Africa to other regions has caused global alarm. A new assay combining recombinase-aided amplification (RAA) and CRISPR/Cas12a technology has been proposed, showing low detection limits and high selectivity for MPXV. A kit with lateral flow strips was developed for on-site screening, enabling easy and rapid MPXV detection without advanced equipment. This assay has the potential to be used for on-site surveillance of MPXV in emerging viral outbreaks.
ANALYTICAL METHODS
(2023)