期刊
RSC ADVANCES
卷 6, 期 11, 页码 8572-8579出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5ra23580d
关键词
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资金
- National Natural Science Foundation of China [20573091]
- Ordinary University Graduate Research Innovation programme of Jiangsu Higher Education Institutions [CXZZ13_0893]
Fe3O4/polyaniline@mesoporous SiO2 yolk@shell nanostructures have been synthesized as multifunctional drug nanocarriers: the nanocavity in the yolk@ shell nanostructures ensures high encapsulation of drugs, the presence of conducting polymer and mesoporous SiO2 shell guarantee controlled release of drugs, and the Fe3O4 core ensures targeted location through a magnetic response. Doxorubicin was incorporated into Fe3O4/polyaniline@mesoporous SiO2 yolk@shell nanocarriers with remarkably high entrapment efficiency, and the delivery system has an obvious sustained release effect.
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