Pharmacological Management of Childhood-Onset Systemic Lupus Erythematosus

Randomized, Double-Blind, Dose-Escalation Trial of Triptorelin for Ovary Protection in Childhood-Onset Systemic Lupus Erythematosus

(2015) Hermine I. Brunner et al.   Arthritis & Rheumatology

A phase 2, randomised, placebo-controlled clinical trial of blisibimod, an inhibitor of B cell activating factor, in patients with moderate-to-severe systemic lupus erythematosus, the PEARL-SC study

(2014) R A Furie et al.   ANNALS OF THE RHEUMATIC DISEASES

Efficacy and safety of atacicept for prevention of flares in patients with moderate-to-severe systemic lupus erythematosus (SLE): 52-week data (APRIL-SLE randomised trial)

(2014) David Isenberg et al.   ANNALS OF THE RHEUMATIC DISEASES

New insights into the pathogenesis and management of lupus in children

(2014) A. Midgley et al.   ARCHIVES OF DISEASE IN CHILDHOOD

Methodology of clinical trials for rare diseases

(2014) Catrin Tudur Smith et al.   BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY

Innate and adaptive immunity

(2014)   LUPUS

Methotrexate in systemic lupus erythematosus: a systematic review of its efficacy

(2014) R Sakthiswary et al.   LUPUS

The indications, efficacy and adverse events of rituximab in a large cohort of patients with juvenile-onset SLE

(2014) L Watson et al.   LUPUS

Mycophenolate mofetil as maintenance therapy for childhood-onset systemic lupus erythematosus patients with severe lupus nephritis

(2014) Toshitaka Kizawa et al.   Modern Rheumatology

The influence of the European paediatric regulation on marketing authorisation of orphan drugs for children

(2014) Annemarie Rosan Kreeftmeijer-Vegter et al.   Orphanet Journal of Rare Diseases

Prolonged improvement of childhood onset systemic lupus erythematosus following systematic administration of rituximab and cyclophosphamide

(2014) Thomas JA Lehman et al.   Pediatric Rheumatology

Efficacy and safety of epratuzumab in patients with moderate/severe active systemic lupus erythematosus: results from EMBLEM, a phase IIb, randomised, double-blind, placebo-controlled, multicentre study

(2013) Daniel J Wallace et al.   ANNALS OF THE RHEUMATIC DISEASES

Tabalumab in Rheumatoid Arthritis Patients With an Inadequate Response to Methotrexate and Naive to Biologic Therapy: A Phase II, Randomized, Placebo-Controlled Trial

(2013) M. C. Genovese et al.   ARTHRITIS AND RHEUMATISM

Efficacy and Safety of Ocrelizumab in Active Proliferative Lupus Nephritis: Results From a Randomized, Double-Blind, Phase III Study

(2013) Eduardo F. Mysler et al.   ARTHRITIS AND RHEUMATISM

Sifalimumab, a Human Anti-Interferon-α Monoclonal Antibody, in Systemic Lupus Erythematosus: A Phase I Randomized, Controlled, Dose-Escalation Study

(2013) Michelle Petri et al.   ARTHRITIS AND RHEUMATISM

Biologics in SLE: Towards new approaches

(2013) Ronald F. van Vollenhoven et al.   BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY

Challenges and opportunities in SLE clinical trials

(2013) Ronald F. van Vollenhoven   CURRENT OPINION IN RHEUMATOLOGY

The development of genome-wide association studies and their application to complex diseases, including lupus

(2013) J Bentham et al.   LUPUS

PReS-FINAL-2356: A comparison of the American college of rheumatology and the systemic lupus international collaborating clinics classification criteria for systemic lupus erythematosus using data from the uk juvenile systemic lupus erythematosus cohort study

(2013) O Lloyd et al.   Pediatric Rheumatology

Efficacy and safety of epratuzumab in patients with moderate/severe flaring systemic lupus erythematosus: results from two randomized, double-blind, placebo-controlled, multicentre studies (ALLEVIATE) and follow-up

(2013) Daniel J. Wallace et al.   RHEUMATOLOGY

Tabalumab, an anti-BAFF monoclonal antibody, in patients with active rheumatoid arthritis with an inadequate response to TNF inhibitors

(2012) Mark C Genovese et al.   ANNALS OF THE RHEUMATIC DISEASES

Lupuzor/P140 peptide in patients with systemic lupus erythematosus: a randomised, double-blind, placebo-controlled phase IIb clinical trial

(2012) Robert Zimmer et al.   ANNALS OF THE RHEUMATIC DISEASES

Joint European League Against Rheumatism and European Renal Association–European Dialysis and Transplant Association (EULAR/ERA-EDTA) recommendations for the management of adult and paediatric lupus nephritis

(2012) George K Bertsias et al.   ANNALS OF THE RHEUMATIC DISEASES

Safety and pharmacodynamics of rontalizumab in patients with systemic lupus erythematosus: Results of a phase I, placebo-controlled, double-blind, dose-escalation study

(2012) Jacqueline M. McBride et al.   ARTHRITIS AND RHEUMATISM

Disease activity, severity, and damage in the UK juvenile-onset systemic lupus erythematosus cohort

(2012) Louise Watson et al.   ARTHRITIS AND RHEUMATISM

Efficacy and safety of rituximab in patients with active proliferative lupus nephritis: The lupus nephritis assessment with rituximab study

(2012) Brad H. Rovin et al.   ARTHRITIS AND RHEUMATISM

Derivation and validation of the Systemic Lupus International Collaborating Clinics classification criteria for systemic lupus erythematosus

(2012) Michelle Petri et al.   ARTHRITIS AND RHEUMATISM

The origin and properties of extracellular DNA: From PAMP to DAMP

(2012) David S. Pisetsky   CLINICAL IMMUNOLOGY

Intravenous cyclophosphamide combined with steroids in pediatric onset severe lupus nephritis

(2012) Prayong Vachvanichsanong et al.   INTERNATIONAL UROLOGY AND NEPHROLOGY

Safety profile of belimumab: pooled data from placebo-controlled phase 2 and 3 studies in patients with systemic lupus erythematosus

(2012) DJ Wallace et al.   LUPUS

Efficacy of mycophenolate mofetil in adolescent patients with lupus nephritis: evidence from a two-phase, prospective randomized trial

(2012) R Sundel et al.   LUPUS

Expression of Toll-like receptors and their detection of nuclear self-antigen leading to immune activation in JSLE

(2012) A. Midgley et al.   RHEUMATOLOGY

Adding to complexity: comorbidity in paediatric rheumatic disease

(2012) E. M. D. Smith et al.   RHEUMATOLOGY

Glucocorticoid use and abuse in SLE

(2012) G. Ruiz-Irastorza et al.   RHEUMATOLOGY

Unmet medical needs in systemic lupus erythematosus

(2012) Aisha Lateef et al.   ARTHRITIS RESEARCH & THERAPY

Atacicept in combination with MMF and corticosteroids in lupus nephritis: results of a prematurely terminated trial

(2012) Ellen M Ginzler et al.   ARTHRITIS RESEARCH & THERAPY

Biologic Differences Between Various Inhibitors of the BLyS/BAFF Pathway: Should We Expect Differences Between Belimumab and Other Inhibitors in Development?

(2012) William Stohl   Current Rheumatology Reports

A phase III, randomized, placebo-controlled study of belimumab, a monoclonal antibody that inhibits B lymphocyte stimulator, in patients with systemic lupus erythematosus

(2011) Richard Furie et al.   ARTHRITIS AND RHEUMATISM

First appearance and location of catecholaminergic cells during experimental arthritis and elimination by chemical sympathectomy

(2011) Silvia Capellino et al.   ARTHRITIS AND RHEUMATISM

Efficacy and safety of belimumab in patients with active systemic lupus erythematosus: a randomised, placebo-controlled, phase 3 trial

(2011) Sandra V Navarra et al.   LANCET

Consensus treatment plans for induction therapy of newly diagnosed proliferative lupus nephritis in juvenile systemic lupus erythematosus

(2011) Rina Mina et al.   ARTHRITIS CARE & RESEARCH

EULAR recommendations for the management of systemic lupus erythematosus with neuropsychiatric manifestations: report of a task force of the EULAR standing committee for clinical affairs

(2010) G. K. Bertsias et al.   ANNALS OF THE RHEUMATIC DISEASES

The efficacy and safety of abatacept in patients with non-life-threatening manifestations of systemic lupus erythematosus: Results of a twelve-month, multicenter, exploratory, phase IIb, randomized, double-blind, placebo-controlled trial

(2010) J. T. Merrill et al.   ARTHRITIS AND RHEUMATISM

Tocilizumab in systemic lupus erythematosus: Data on safety, preliminary efficacy, and impact on circulating plasma cells from an open-label phase I dosage-escalation study

(2010) Gabor G. Illei et al.   ARTHRITIS AND RHEUMATISM

B Cell-Targeted Therapies for Systemic Lupus Erythematosus

(2010) R. John Looney   DRUGS

Thiopurine S-methyltransferase (TPMT) assessment prior to starting thiopurine drug treatment; a pharmacogenomic test whose time has come

(2010) L. T. Ford et al.   JOURNAL OF CLINICAL PATHOLOGY

T cells as therapeutic targets in SLE

(2010) José C. Crispín et al.   Nature Reviews Rheumatology

Hydroxychloroquine in SLE: old drug, new perspectives

(2010) Thomas Dörner   Nature Reviews Rheumatology

Prevalence and burden of pediatric-onset systemic lupus erythematosus

(2010) Sylvia Kamphuis et al.   Nature Reviews Rheumatology

American College of Rheumatology 2010 recommendations for the prevention and treatment of glucocorticoid-induced osteoporosis

(2010) Jennifer M. Grossman et al.   ARTHRITIS CARE & RESEARCH

Denosumab-mediated increase in hand bone mineral density associated with decreased progression of bone erosion in rheumatoid arthritis patients

(2010) A. Deodhar et al.   ARTHRITIS CARE & RESEARCH

The role of neutrophil apoptosis in juvenile-onset systemic lupus erythematosus

(2009) Angela Midgley et al.   ARTHRITIS AND RHEUMATISM

Protective effect of hydroxychloroquine on renal damage in patients with lupus nephritis: LXV, data from a multiethnic US cohort

(2009) Guillermo J. Pons-Estel et al.   ARTHRITIS AND RHEUMATISM

Efficacy and safety of rituximab in moderately-to-severely active systemic lupus erythematosus: The randomized, double-blind, phase ii/iii systemic lupus erythematosus evaluation of rituximab trial

(2009) Joan T. Merrill et al.   ARTHRITIS AND RHEUMATISM

Prednisone, Lupus Activity, and Permanent Organ Damage

(2009) M. THAMER et al.   JOURNAL OF RHEUMATOLOGY

Ethnic Differences in Pediatric Systemic Lupus Erythematosus

(2009) L. T. HIRAKI et al.   JOURNAL OF RHEUMATOLOGY

Mycophenolate Mofetil versus Cyclophosphamide for Induction Treatment of Lupus Nephritis

(2009) G. B. Appel et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Damage and mortality in a group of British patients with systemic lupus erythematosus followed up for over 10 years

(2009) S. A. Chambers et al.   RHEUMATOLOGY

Juvenile-onset systemic lupus erythematosus: different clinical and serological pattern than adult-onset systemic lupus erythematosus

(2008) I E A Hoffman et al.   ANNALS OF THE RHEUMATIC DISEASES

Association of plasma B lymphocyte stimulator levels and disease activity in systemic lupus erythematosus

(2008) Michelle Petri et al.   ARTHRITIS AND RHEUMATISM

Abetimus sodium for renal flare in systemic lupus erythematosus: Results of a randomized, controlled phase III trial

(2008) Mario H. Cardiel et al.   ARTHRITIS AND RHEUMATISM

Denosumab treatment effects on structural damage, bone mineral density, and bone turnover in rheumatoid arthritis: A twelve-month, multicenter, randomized, double-blind, placebo-controlled, phase II clinical trial

(2008) Stanley B. Cohen et al.   ARTHRITIS AND RHEUMATISM

Difference in disease features between childhood-onset and adult-onset systemic lupus erythematosus

(2008) Hermine I. Brunner et al.   ARTHRITIS AND RHEUMATISM

APRIL is critical for plasmablast survival in the bone marrow and poorly expressed by early-life bone marrow stromal cells

(2008) E. Belnoue et al.   BLOOD

A Modular Analysis Framework for Blood Genomics Studies: Application to Systemic Lupus Erythematosus

(2008) Damien Chaussabel et al.   IMMUNITY

Adolescent onset of lupus results in more aggressive disease and worse outcomes: results of a nested matched case–control study within LUMINA, a multiethnic US cohort (LUMINA LVII)

(2008) LB Tucker et al.   LUPUS

B cell depletion therapy for 19 patients with refractory systemic lupus erythematosus

(2007) A Podolskaya et al.   ARCHIVES OF DISEASE IN CHILDHOOD

Clinical and Laboratory Characteristics and Long-Term Outcome of Pediatric Systemic Lupus Erythematosus: A Longitudinal Study

(2007) Linda T. Hiraki et al.   JOURNAL OF PEDIATRICS