Improving Outcomes in Infantile Spasms: Role of Pharmacotherapy

Response to treatment in a prospective national infantile spasms cohort

(2016) Kelly G. Knupp et al.   ANNALS OF NEUROLOGY

Prevention of infantile spasms relapse: Zonisamide and topiramate provide no benefit

(2016) Rajsekar R. Rajaraman et al.   EPILEPSIA

Everolimus for subependymal giant cell astrocytoma: 5-year final analysis

(2015) David N. Franz et al.   ANNALS OF NEUROLOGY

OP50 – 3017: The International Collaborative Infantile Spasms Study (ICISS) comparing hormonal therapies (prednisolone or tetracosactide depot) and vigabatrin versus hormonal therapies alone in the treatment of infantile spasms: Early clinical outcome

(2015) F.J.K. O'Callaghan et al.   EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY

Infantile Spasms Respond Poorly to Topiramate

(2015) Amanda Weber et al.   PEDIATRIC NEUROLOGY

Long-term outcome in children with infantile spasms treated with vigabatrin: A cohort of 180 patients

(2014) Milena Djuric et al.   EPILEPSIA

The Efficacy of Moderate-to-High Dose Oral Prednisolone Versus Low-to-Moderate Dose Intramuscular Corticotropin for Improvement of Hypsarrhythmia in West Syndrome: A Randomized, Single-Blind, Parallel Clinical Trial

(2014) Jithangi Wanigasinghe et al.   PEDIATRIC NEUROLOGY

An investigation into the relationship between vigabatrin, movement disorders, and brain magnetic resonance imaging abnormalities in children with infantile spasms

(2013) Choong YI Fong et al.   DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY

Mammalian Target of Rapamycin (mTOR) Inhibition: Potential for Antiseizure, Antiepileptogenic, and Epileptostatic Therapy

(2012) Robin C. C. Ryther et al.   Current Neurology and Neuroscience Reports

A randomized controlled trial of flunarizine as add-on therapy and effect on cognitive outcome in children with infantile spasms

(2012) Jonathan Y. Bitton et al.   EPILEPSIA

Finding a better drug for epilepsy: The mTOR pathway as an antiepileptogenic target

(2012) Aristea S. Galanopoulou et al.   EPILEPSIA

Evidence-based guideline update: Medical treatment of infantile spasms: Report of the Guideline Development Subcommittee of the American Academy of Neurology and the Practice Committee of the Child Neurology Society

(2012) C. Y. Go et al.   NEUROLOGY

Intravenous levetiracetam in acute repetitive seizures and status epilepticus in children: Experience from a children's hospital

(2012) A. McTague et al.   SEIZURE-EUROPEAN JOURNAL OF EPILEPSY

The effect of lead time to treatment and of age of onset on developmental outcome at 4 years in infantile spasms: Evidence from the United Kingdom Infantile Spasms Study

(2011) Finbar J. K. O’Callaghan et al.   EPILEPSIA

A prospective study on the treatment of infantile spasms with first-line topiramate followed by low-dose ACTH

(2011) Xiaobo Zhu et al.   EPILEPSY RESEARCH

Treatment of Infantile Spasms

(2011) Carl E. Stafstrom et al.   JOURNAL OF CHILD NEUROLOGY

A pulse rapamycin therapy for infantile spasms and associated cognitive decline

(2011) Emmanuel Raffo et al.   NEUROBIOLOGY OF DISEASE

Developmental and epilepsy outcomes at age 4 years in the UKISS trial comparing hormonal treatments to vigabatrin for infantile spasms: a multi-centre randomised trial

(2010) K. Darke et al.   ARCHIVES OF DISEASE IN CHILDHOOD

INFANTILE SPASMS TREATED WITH HIGH DOSES OF SODIUM VALPROATE: INITIAL RESPONSE AND FOLLOW-UP

(2010) J. M. Prats et al.   DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY

Modeling new therapies for infantile spasms

(2010) Lenka Chudomelova et al.   EPILEPSIA

Revised terminology and concepts for organization of seizures and epilepsies: Report of the ILAE Commission on Classification and Terminology, 2005-2009

(2010) Anne T. Berg et al.   EPILEPSIA

Outcomes in Treatment of Infantile Spasms With Pulse Methylprednisolone

(2010) John R. Mytinger et al.   JOURNAL OF CHILD NEUROLOGY

Vigabatrin for the Treatment of Infantile Spasms: Final Report of a Randomized Trial

(2010) Roy D. Elterman et al.   JOURNAL OF CHILD NEUROLOGY

Topiramate and Adrenocorticotropic Hormone (ACTH) as Initial Treatment for Infantile Spasms

(2009) Bradley Peltzer et al.   JOURNAL OF CHILD NEUROLOGY

Inhibition of the Mammalian Target of Rapamycin Signaling Pathway Suppresses Dentate Granule Cell Axon Sprouting in a Rodent Model of Temporal Lobe Epilepsy

(2009) P. S. Buckmaster et al.   JOURNAL OF NEUROSCIENCE

Evaluation of Open-Label Topiramate as Primary or Adjunctive Therapy in Infantile Spasms

(2008) Li-Ping Zou et al.   CLINICAL NEUROPHARMACOLOGY

Cerebral MRI abnormalities associated with vigabatrin therapy

(2008) Phillip L. Pearl et al.   EPILEPSIA

RESPONSE OF INFANTILE SPASMS TO LEVETIRACETAM

(2008) M. A. Mikati et al.   NEUROLOGY