Article
Cardiac & Cardiovascular Systems
Hyo Eun Park, Goh Eun Chung, Heesun Lee, Min Joo Kim, Su-Yeon Choi, Wonjae Lee, Ji Won Yoon
Summary: This study evaluated the relationship between low skeletal muscle mass and cardio-ankle vascular index (CAVI) and found a significant and independent association between low muscle mass and increased CAVI. This suggests that low muscle mass should be considered in assessing the risk of atherosclerosis in asymptomatic individuals.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Nutrition & Dietetics
William D. Fairfield, Dennis M. Minton, Christian J. Elliehausen, Alexander D. Nichol, Taylor L. Cook, John A. Rathmacher, Lisa M. Pitchford, Scott A. Paluska, Adam J. Kuchnia, Jacob M. Allen, Adam R. Konopka
Summary: HMB + D supplementation can increase skeletal muscle volume, decrease intermuscular adipose tissue, and prevent muscle loss in middle-aged women.
Review
Oncology
Maximilian Koeppel, Katlynn Mathis, Kathryn H. Schmitz, Joachim Wiskemann
Summary: Resistance training can effectively counteract muscle loss in cancer patients, with better results in a supervised setting.
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
(2021)
Review
Multidisciplinary Sciences
Victor Sabino de Queiros, Nicholas Rolnick, Phelipe Wilde de Alcantara Varela, Breno Guilherme de Araujo Tinoco Cabral, Paulo Moreira Silva Dantas
Summary: High-frequency BFR training can generate significant neuromuscular adaptations, but strength declines and muscle fiber atrophy were reported in resistance training to failure. There is a lack of studies comparing low-frequency and high-frequency in short-term BFR training. Comparisons between resistance exercises of similar intensities are also lacking, limiting conclusions on the specific effects of proximity to failure or BFR.
Article
Biochemistry & Molecular Biology
Dong Yi, Maki Yoshikawa, Takeshi Sugimoto, Keigo Tomoo, Yoko Okada, Takeshi Hashimoto
Summary: This study investigated the effects and mechanism of maca on muscle hypertrophy, and found that maca may promote muscle hypertrophy, differentiation, and maturation through muscle hypertrophic signaling pathways such as Akt and mTOR.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Medicine, General & Internal
Hironaga Ogawa, Toshiaki Nakajima, Ikuko Shibasaki, Takahisa Nasuno, Hiroyuki Kaneda, Satoshi Katayanagi, Hayato Ishizaka, Yuta Mizushima, Azusa Uematsu, Tomohiro Yasuda, Hiroshi Yagi, Shigeru Toyoda, Tibor Hortobagyi, Takashi Mizushima, Teruo Inoue, Hirotsugu Fukuda
Summary: This study investigated the effects of low-intensity resistance training combined with moderate blood flow restriction on muscle strength and size in patients early after cardiac surgery. The results showed that KAATSU RT can safely increase skeletal muscle strength and size, with improvements in muscle thickness, walking speed, and knee extensor strength.
JOURNAL OF CLINICAL MEDICINE
(2021)
Review
Biochemistry & Molecular Biology
Kevin A. Murach, Christopher S. Fry, Esther E. Dupont-Versteegden, John J. McCarthy, Charlotte A. Peterson
Summary: Satellite cells play crucial roles in adult skeletal muscle adaptation to loading, contributing new myonuclei, supporting hypertrophy, repair of membrane damage, transcriptional output, and communication within the niche. While adaptation can occur without satellite cells in the short term, their participation is ultimately necessary for full adaptive potential in growth, function, and coordination.
Review
Geriatrics & Gerontology
Christopher Hurst, Sian M. Robinson, Miles D. Witham, Richard M. Dodds, Antoneta Granic, Charlotte Buckland, Sarah De Biase, Susanne Finnegan, Lynn Rochester, Dawn A. Skelton, Avan A. Sayer
Summary: Sarcopenia is a muscle disorder characterized by reduced strength and mass, with resistance exercise recommended as the primary treatment. However, evidence on its benefits for sarcopenic older adults is limited, and optimal prescription and delivery remain unclear. The proposed resistance exercise program for sarcopenia includes two sessions per week focusing on upper- and lower-body exercises with high effort, serving as a valuable resource for clinicians and researchers.
Article
Multidisciplinary Sciences
Kyung-Wan Baek, So-Jeong Kim, Bo-Gyu Kim, Youn-Kwan Jung, Young-Sool Hah, Hyo Youl Moon, Jun-Il Yoo, Jin Sung Park, Ji-Seok Kim
Summary: Long-term aerobic exercise can maintain skeletal muscle mass, quality, and fitness levels in super-aged mice, as well as maintain high levels of angiogenic capacity.
Review
Multidisciplinary Sciences
Elisio A. Pereira-Neto, Hayley Lewthwaite, Terry Boyle, Kylie Johnston, Hunter Bennett, Marie T. Williams
Summary: There is limited evidence on the effects of BFRE on vascular function, predominantly among healthy young adults. Specific dynamic resistance exercise protocols with blood flow restriction may have a positive impact on endothelial function, warranting further investigation.
Article
Physiology
Yan Zhao, Jason Cholewa, Huayu Shang, Yueqin Yang, Xiaomin Ding, Shaosheng Liu, Zhi Xia, Nelo Eidy Zanchi, Qianjin Wang
Summary: Studies have shown that resistance exercise can increase muscle protein synthesis and deposition, leading to muscle hypertrophy through the LeuRS/mTOR signaling pathway.
FRONTIERS IN PHYSIOLOGY
(2021)
Review
Physiology
Hugo Falqueto, Marcelo Rodrigues dos Santos, Leandro H. Manfredi
Summary: Sarcopenia is a health concern characterized by reduced physical function and muscle mass. Exercise training can help improve these conditions, but it may not be effective for many elderly individuals. Thus, the use of anabolic-androgenic steroids may be a viable strategy.
FRONTIERS IN PHYSIOLOGY
(2022)
Review
Food Science & Technology
Gavriela Voulgaridou, Sophia D. Papadopoulou, Maria Spanoudaki, Fovi S. Kondyli, Ioanna Alexandropoulou, Stella Michailidou, Paul Zarogoulidis, Dimitris Matthaios, Dimitrios Giannakidis, Maria Romanidou, Sousana K. Papadopoulou
Summary: This study aimed to review the current evidence on the independent and combined effects of diet and exercise and their impact on skeletal muscle mass in the elderly population. The combination of exercise and diet is known to be a potent anabolic stimulus through stimulation of muscle protein synthesis from amino acids. Aging is strongly associated with a generalized deterioration of physiological function, including a progressive reduction in skeletal muscle mass. Sarcopenia, an age-related syndrome, is primarily used to describe the gradual and generalized loss of skeletal muscle mass and function. Multimodal training and adequate protein intake have been recognized as effective interventions to promote skeletal muscle growth in the elderly.
Article
Sport Sciences
Emerson L. Teixeira, Vitor de Salles Painelli, Carla Silva-Batista, Talita de Souza Barros, Ariel R. Longo, Thiago Lasevicius, Brad J. Schoenfeld, Andre Y. Aihara, Bergson de Almeida Peres
Summary: Short-term gains in muscle strength and hypertrophy from resistance training with blood flow restriction are not maintained after a 12-day detraining period, and the application of BFR without exercise stimulus does not attenuate these losses.
JOURNAL OF STRENGTH AND CONDITIONING RESEARCH
(2021)
Article
Geriatrics & Gerontology
Anoop T. Balachandran, William J. Evans, Peggy M. Cawthon, Yipeng Wang, Mahalakshmi Shankaran, Marc K. Hellerstein, Peihua Qiu, Todd Manini
Summary: The D3Cr dilution method provides a direct measure of skeletal muscle mass and is strongly associated with health-related outcomes in older men. However, its sensitivity to detect changes in muscle mass due to intervention is limited.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2023)