Article
Medicine, General & Internal
Leonie Schoch, Pablo Sutelman, Rosa Suades, Lina Badimon, Isabel Moreno-Indias, Gemma Vilahur
Summary: This study investigates the impact of diet and rosuvastatin interventions on gut microbiota composition in hypercholesterolemic pigs. The results show that a low-fat diet improves the diversity and metabolic profile of gut microbiota, while rosuvastatin treatment has no effects on microbiota and lipid profile.
EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
(2023)
Article
Microbiology
Yifan Zhong, Jiahong Cao, Zhaoxi Deng, Yanfei Ma, Jianxin Liu, Haifeng Wang
Summary: The combination of FMT from different donors with dietary fiber intervention can result in varied patterns of gut microbiota composition, with dietary fiber potentially playing a more critical role in shaping gut microbiota compared to the FMT donor. Strategies based on dietary fiber can influence the effectiveness of FMT in the recipient.
FRONTIERS IN MICROBIOLOGY
(2021)
Article
Agriculture, Dairy & Animal Science
Tanya L. Nowland, Roy N. Kirkwood, Kate J. Plush, Mary D. Barton, Valeria A. Torok
Summary: The study found that the gut microbiota of piglets born to primiparous sows differed from those born to multiparous sows, with reduced growth and survival. Contact with multiparous sow feces may improve offspring performance by influencing gut microbiota.
JOURNAL OF ANIMAL SCIENCE
(2021)
Review
Agriculture, Dairy & Animal Science
Marcos Elias Duarte, Sung Woo Kim
Summary: This review article provides updated scientific information on the interaction among intestinal microbiota, dietary components, and intestinal health of pigs. The composition of the microbiota is mainly influenced by diet and feed additives, and plays a key role in modulating the immune system. The evaluation of mucosa-associated microbiota is more effective in assessing its impact on health parameters.
Article
Gastroenterology & Hepatology
Henrik M. Roager, Catherine Stanton, Lindsay J. Hall
Summary: The development of the infant gut microbiome is crucial for the microbiome ecology, function, and host health. Technological advancements now allow for better profiling of metabolites in the infant gut, providing insights into the roles of microbial-derived metabolites in shaping the microbiome community and influencing host-microbial interactions during early life. This review summarizes the current knowledge on the development of the infant gut microbiota and metabolism within the first year of life, emphasizing the importance of microbial metabolites in enhancing our understanding of early life interactions.
Review
Biology
Justine Keathley, Jessica White, Gregor Reid
Summary: The recognition of the importance of microbes in human life has led to research on manipulating them for better health outcomes. However, there is currently no consensus on dietary recommendations to complement ingested organisms for improved health. This review aims to discuss the use of beneficial microbes, such as probiotics, fermented foods, and donor feces, in managing health, and explores the rationale for selecting specific microbial strains and aligning diets to support their growth in the gut.
Review
Nutrition & Dietetics
Ana Alvarez-Mercado, Julio Plaza-Diaz
Summary: Polysaccharides, composed of more than ten monosaccharides, have wide distribution and complex structure, playing key roles in immune modulation and gut microbiota.
Article
Microbiology
Bing Xia, Ruqing Zhong, Weida Wu, Chengzeng Luo, Qingshi Meng, Qingtao Gao, Yong Zhao, Liang Chen, Sheng Zhang, Xin Zhao, Hongfu Zhang
Summary: Post-weaning diarrhea in piglets disrupts the colonic mucus layer and causes aberrant mucin O-glycans. This leads to gut microenvironment impairment, compromised epithelial barrier integrity, enhanced susceptibility to inflammation, and mild growth faltering. The activation of inflammasomes and autophagy restriction along with changes in microbiota are likely associated with diarrheal pathogenesis.
Article
Gastroenterology & Hepatology
Clara Delaroque, Gary D. D. Wu, Charlene Compher, Josephine Ni, Lindsey Albenberg, Qing Liu, Yuan Tian, Andrew D. D. Patterson, James D. D. Lewis, Andrew T. T. Gewirtz, Benoit Chassaing
Summary: The study found that individual differences in diet and day-to-day variations in diet have a significant impact on the composition of the gut microbiota. Normalization of diet can reduce intra-individual variation and decrease the pro-inflammatory potential of the microbiota.
Article
Biochemistry & Molecular Biology
Tingwei Wang, Yongli Ye, Jian Ji, Shuang Zhang, Xingxing Yang, Jiayuan Xu, Jia-Sheng Wang, Zhiyuan Chen, Bangen Xia, Hongfang Shen, Ruowei Xia, Wenqin Shi, Xiulan Sun
Summary: Astilbin consumption has significant anti-obesity and anti-inflammatory effects in high-fat diet mice. It improves gut microbial dysbiosis, enhances intestinal carbohydrate and lipid metabolism, and protects the integrity of the intestinal barrier. Astilbin is a potential prebiotic for the prevention of gut-liver axis damage and metabolic disruption in obese individuals.
Article
Veterinary Sciences
Cui Zhu, Jingsen Yang, Qiwen Wu, Jingping Chen, Xuefen Yang, Li Wang, Zongyong Jiang
Summary: This study investigated the effect of a low protein diet on various aspects of finishing pigs, including growth performance, nitrogen emission, carcass traits, meat quality, and gut microbiota. The results showed that the low protein diet reduced nitrogen emission, improved meat quality, and had no significant impact on growth performance. It also regulated antioxidant capacity and gene expression related to fat metabolism, as well as modulated the composition of gut microbiota.
FRONTIERS IN VETERINARY SCIENCE
(2022)
Article
Microbiology
Xupeng Zang, Wenjing Wang, Shengchen Gu, Ting Gu, Huaqiang Yang, Enqin Zheng, Zheng Xu, Sixiu Huang, Zicong Li, Gengyuan Cai, Linjun Hong, Zhenfang Wu
Summary: This study reveals the dynamic changes of sow vaginal microbiotas and their roles in pregnancy development. It also provides insights into the microbe-host interactions in the reproductive tract, which may lead to new research and intervention targets for improving pregnancy development through modulating lower reproductive tract microbiota.
Article
Biochemistry & Molecular Biology
Zhuohong Tang, Ting Luo, Peng Huang, Mi Luo, Jianghua Zhu, Xing Wang, Qingmei Lin, Zihao He, Pingming Gao, Shuwen Liu
Summary: Gestational diabetes mellitus is a global health concern, and nuciferine shows potential therapeutic efficacy in GDM mice by improving glycolipid disorders, protecting critical organs, and correcting intestinal dysbacteriosis.
Article
Nutrition & Dietetics
Maite Villasenor-Aranguren, Carles Roses, Jose Ignacio Riezu-Boj, Miguel Lopez-Yoldi, Omar Ramos-Lopez, Anna M. Barcelo, Fermin Milagro
Summary: This study analyzed the relationship between gut microbiota composition and health parameters in the Spanish population. It found that certain bacterial strains were associated with metabolic health and identified associations between bacteria and specific food groups.
Article
Immunology
Yifan Zhong, Dongyan Fu, Zhaoxi Deng, Wenjie Tang, Jiangdi Mao, Tao Zhu, Yu Zhang, Jianxin Liu, Haifeng Wang
Summary: Wild pig gut bacteria can serve as a good source for discovering potential probiotic strains due to their high tolerance and resistance to diseases. In this study, the feces of wild pigs were sequenced and shown to have a higher relative abundance of Lactobacillus compared to domestic pigs. A total of 11 lactic acid bacteria strains were isolated, and their mixture was orally administered to mice for 3 weeks. The mice showed increased LAB counts in feces and ileum, as well as alterations in specific bacterial genera. Administration of the LAB strains also attenuated inflammation of the liver and gut in mice challenged with Escherichia coli. This study highlights the importance of gut bacterial diversity and the immunomodulation effects of LAB strains in gut health.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Gastroenterology & Hepatology
Anna Janina Engstler, Tobias Aumiller, Christian Degen, Marion Duerr, Eva Weiss, Ina Barbara Maier, Joern Markus Schattenberg, Cheng Jun Jin, Cathrin Sellmann, Ina Bergheim
Article
Agriculture, Dairy & Animal Science
T. Aumiller, R. Mosenthin, F. Rink, K. Hartung, E. Weiss
JOURNAL OF ANIMAL PHYSIOLOGY AND ANIMAL NUTRITION
(2015)
Article
Agriculture, Multidisciplinary
Eva Weiss, Tobias Aumiller, Hanna K. Spindler, Pia Rosenfelder, Meike Eklund, Maren Witzig, Henry Jorgensen, Knud Erik Bach Knudsen, Rainer Mosenthin
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2016)
Review
Agriculture, Dairy & Animal Science
Tobias Aumiller, Rainer Mosenthin, Eva Weiss
Article
Agriculture, Multidisciplinary
Henry Reyer, Juergen Zentek, Klaus Maenner, Ibrahim M. I. Youssef, Tobias Aumiller, Julian Weghuber, Klaus Wimmers, Andreas S. Mueller
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2017)
Article
Multidisciplinary Sciences
Sonja N. Heinritz, Eva Weiss, Meike Eklund, Tobias Aumiller, Sandrine Louis, Andreas Rings, Sabine Messner, Amelia Camarinha-Silva, Jana Seifert, Stephan C. Bischoff, Rainer Mosenthin
Article
Agriculture, Dairy & Animal Science
Charlotte Maria Elisabeth Heyer, Sonja Schmucker, Katharina Burbach, Eva Weiss, Meike Eklund, Tobias Aumiller, Filippo Capezzone, Julia Steuber, Markus Rodehutscord, Ludwig Eduard Hoelzle, Jana Seifert, Rainer Mosenthin, Volker Stefanski
JOURNAL OF ANIMAL PHYSIOLOGY AND ANIMAL NUTRITION
(2019)
Article
Agriculture, Dairy & Animal Science
David Reyes-Camacho, Ester Vinyeta, Jose Francisco Perez, Tobias Aumiller, Lourdes Criado, Laurentiu Mihai Palade, Ionelia Taranu, Josep M. Folch, M. Angels Calvo, Jan Dirk Van der Klis, David Sola-Oriol
JOURNAL OF ANIMAL SCIENCE
(2020)
Article
Biochemistry & Molecular Biology
Georg Sandner, Andreas S. Mueller, Xiaodan Zhou, Verena Stadlbauer, Bettina Schwarzinger, Clemens Schwarzinger, Uwe Wenzel, Klaus Maenner, Jan Dirk van der Klis, Stefan Hirtenlehner, Tobias Aumiller, Julian Weghuber
Article
Biochemistry & Molecular Biology
Verena Stadlbauer, Cathrina Neuhauser, Tobias Aumiller, Alexander Stallinger, Marcus Iken, Julian Weghuber
Summary: Type 2 diabetes mellitus is associated with reduced uptake of glucose facilitated by GLUT4, prompting the need for novel medications. A high-content screen of over 600 plant extracts identified 30 potential hits, with PI3 kinase identified as a key signaling target for GLUT4 translocation. Effective extracts were able to lower blood glucose levels in chicken embryos, showcasing their potential as antidiabetic pharmaceuticals or nutraceuticals.
Article
Agriculture, Dairy & Animal Science
David Reyes-Camacho, Jose F. Perez, Ester Vinyeta, Tobias Aumiller, Jan D. Van der Klis, David Sola-Oriol
Summary: The research found that piglets showed preferences for D-limonene and trans-anethole but aversion to eucalyptol. However, prenatal exposure to these compounds did not help overcome the innate aversion to eucalyptol.
Article
Veterinary Sciences
David Reyes-Camacho, Jose Francisco Perez, Ester Vinyeta, Tobias Aumiller, Lourdes Criado-Mesas, Josep Maria Folch, Jan Dirk Van der Klis, David Sola-Oriol
Summary: The study found that supplementing gestating hyperprolific sow diets with a specific blend of phytogenic compounds (BPC) can influence neonatal gut morphology and gene expression related to intestinal health. This led to increased villus height and goblet cell volume density in the jejunum, as well as changes in gene expression associated with nutrient transport and immune response.
FRONTIERS IN VETERINARY SCIENCE
(2021)
Article
Toxicology
Peter Lanzerstorfer, Georg Sandner, Johannes Pitsch, Bianca Mascher, Tobias Aumiller, Julian Weghuber
Summary: Essential oils (EOs) have potential toxic properties, even at low concentrations, with rosemary oil showing slightly higher toxicity. In vitro cell culture and C. elegans model experiments revealed negative effects on cell viability, development, and reproduction parameters. Gene expression analysis showed upregulation of xenobiotic and oxidative stress genes in response to EOs. Mucous membrane irritation was observed at relatively low concentrations of the oils.
ARCHIVES OF TOXICOLOGY
(2021)