Article
Multidisciplinary Sciences
Berhe Gebremichael, Hirbo Shore Roba, Alemeshet Getachew, Dejene Tesfaye, Haftu Asmerom
Summary: This systematic review and meta-analysis estimated the pooled prevalence of folate deficiency (FD) among women of reproductive age in Ethiopia. The results showed that FD is a significant public health issue among women of reproductive age in Ethiopia. It is recommended to promote the consumption of folate-rich foods, strengthen folic acid supplementation and adherence, and swiftly implement mandatory folic acid fortification.
Article
Dentistry, Oral Surgery & Medicine
Yu-Hsueh Wu, Yang-Che Wu, Julia Yu-Fong Chang, Yi-Pang Lee, Chun-Pin Chiang, Andy Sun
Summary: This study found significant differences between male and female AG patients in terms of anemia, hematinic deficiencies, and hyperhomocysteinemia, with male patients showing more severe conditions.
JOURNAL OF DENTAL SCIENCES
(2022)
Article
Nutrition & Dietetics
Anne-Sophie Resseguier, Candy Guiguet-Auclair, Anne Debost-Legrand, Anne-Francoise Serre-Sapin, Laurent Gerbaud, Francoise Vendittelli, Marc Ruivard
Summary: This study aimed to estimate the prevalence of anemia in the third trimester of pregnancy and identify predictive parameters for anemia in the first trimester. The results showed that clinical, social, and biochemical parameters were not effective in predicting anemia in the third trimester. It was suggested to perform a simple blood count in the first trimester and offer oral iron supplementation for women with Hb < 120 g/L.
Article
Dentistry, Oral Surgery & Medicine
Yu-Hsueh Wu, Yang-Che Wu, Julia Yu-Fong Chang, Yi-Pang Lee, Chun-Pin Chiang, Andy Sun
Summary: Younger atrophic glossitis (AG) patients have lower serum levels of vitamin B12 and folic acid, a higher frequency of iron deficiency, and a lower frequency of hyperhomocysteinemia compared to older AG patients.
JOURNAL OF DENTAL SCIENCES
(2022)
Article
Nutrition & Dietetics
Juyoung Kim, Jaekwon Lee, Moon-Suhn Ryu
Summary: Anemia, a common nutrition-related disorder worldwide, is linked to zinc deficiency. The study reveals that zinc is essential for erythroid development and heme biosynthesis. Restricting zinc import reduces heme and alpha-globin production, hindering the hemoglobinization of erythroid progenitors. The findings suggest zinc as a potential therapeutic target for anemia and other erythrocyte-related disorders.
Article
Medicine, General & Internal
Giulia Costanzo, Giada Sambugaro, Giulia Mandis, Sofia Vassallo, Angelo Scuteri
Summary: This article identifies vitamin B12 deficiency as a leading cause of pancytopenia among adults through a case study of four patients with megaloblastic anemia. It is found that all patients had documented deficiency of vitamin B12. Although there was no correlation between the severity of anemia and deficiency of the vitamin, the study highlights the importance of recognizing vitamin B12 deficiency as a primary cause of pancytopenia in adults.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Nutrition & Dietetics
Amy Fothergill, Krista S. Crider, Christina B. Johnson, Mical P. Raj, Heather M. Guetterman, Beena Bose, Charles E. Rose, Yan P. Qi, Jennifer L. Williams, Rebecca Kuriyan, Wesley Bonam, Julia L. Finkelstein
Summary: This study aimed to evaluate screening methods for hemoglobin and anemia assessment using paired venous samples. The findings suggest that using a portable hemoglobinometer for screening may incorrectly identify anemic individuals as non-anemic, leading to an underestimation of anemia prevalence.
JOURNAL OF NUTRITION
(2022)
Article
Nutrition & Dietetics
Reagan M. Mogire, John Muthii Muriuki, Alireza Morovat, Alexander J. Mentzer, Emily L. Webb, Wandia Kimita, Francis M. Ndungu, Alex W. Macharia, Clare L. Cutland, Sodiomon B. Sirima, Amidou Diarra, Alfred B. Tiono, Swaib A. Lule, Shabir A. Madhi, Andrew M. Prentice, Philip Bejon, John M. Pettifor, Alison M. Elliott, Adebowale Adeyemo, Thomas N. Williams, Sarah H. Atkinson
Summary: There is a significant association between vitamin D and iron deficiency in African children. The risk of iron deficiency is increased in children with vitamin D deficiency, and vitamin D concentration variably influences iron status. Therefore, the link between vitamin D and iron status should be considered in strategies to manage these nutrient deficiencies.
Article
Pharmacology & Pharmacy
Kamil Sahin, Murat Elevli, Yahya Paksoy, Macit Koldas
Summary: The study aimed to investigate the deficiency rates of iron, zinc, vitamin B12-D, folic acid, anemia frequency in children admitted to pediatric outpatient clinics. Results showed that multiple micronutrient deficiencies are significantly common in Turkey, with an increase in zinc and vitamin D deficiency over the years.
JOURNAL OF PHARMACEUTICAL RESEARCH INTERNATIONAL
(2021)
Article
Public, Environmental & Occupational Health
Jonas S. Sundarakumar, Shafeeq K. Shahul Hameed, Vijayalakshmi Ravindranath
Summary: High burden of vitamin D and B12 deficiencies exists among older, rural-dwelling Indians, with urgent public health strategies needed for prevention of potential negative impacts on cognition, immunity, and frailty in the aging population.
FRONTIERS IN PUBLIC HEALTH
(2021)
Article
Food Science & Technology
Bolun Sun, Panxue Zhang, Huamao Wei, Ru Jia, Tao Huang, Chao Li, Wenge Yang
Summary: This study evaluated the therapeutic effects of hemoglobin from Tegillarca granosa on iron deficiency anemia (IDA) in mice. The results showed that hemoglobin could effectively improve blood parameters and liver morphology associated with IDA, and restore the levels of serum ferritin and soluble transferrin receptor, indicating a potential role as an alternative for iron supplementation.
FOOD RESEARCH INTERNATIONAL
(2022)
Article
Pediatrics
Jagdish Chandra, Pooja Dewan, Praveen Kumar, Amita Mahajan, Preeti Singh, Bhavna Dhingra, Nita Radhakrishnan, Ratna Sharma, Mamta Manglani, Ashok Kumar Rawat, Piyush Gupta, Sunil Gomber, Sunil Bhat, Parag Gaikwad, K. E. Elizabeth, Deepak Bansal, Anand Prakash Dubey, Nitin Shah, Pranoti Kini, Amita Trehan, Kalpana Datta, G. V. Basavraja, Vineet Saxena, Remesh R. Kumar
Summary: Anemia in children is a significant public health problem in our country, with more than 50% of cases being attributed to nutritional deficiency. The prevalence of anemia in children under the age of five has increased from 59% to 67.1% over the past five years. The existing public health programs have not yielded desired results, highlighting the need for nationally accepted guidelines for the diagnosis, treatment, and prevention of nutritional anemia in children.
Article
Biochemistry & Molecular Biology
Omid Mehrpour, Marzieh Modi, Borhan Mansouri, Nemam Ali Azadi, Samaneh Nakhaee, Alireza Amirabadi, Gholamreza Anaei-sarab, Farshad M. Shirazi, Stephanie T. Weiss
Summary: The study revealed that lead-poisoned patients had lower levels of folic acid and vitamin B12, but higher levels of vitamin D. The results suggest that lead may induce folate and vitamin B12 dysregulation. More studies are needed to clarify the relationship between lead exposure and vitamin levels.
BIOLOGICAL TRACE ELEMENT RESEARCH
(2021)
Article
Biochemistry & Molecular Biology
Adam G. Maynard, Boryana Petrova, Naama Kanarek
Summary: This article presents notes from the Folate, Vitamin B12, and One-Carbon Metabolism Conference held in Asheville, North Carolina, USA, from August 14-19, 2022, organized by The Federation of American Societies for Experimental Biology (FASEB). It aims to share the latest research findings in the field with scientists who were unable to attend the conference but are interested in the topic. The research discussed includes various aspects of one-carbon metabolism, such as its biochemical and physiological levels, its role in development and adulthood, and its relevance in diseases like COVID-19, neurodegeneration, and cancer.
Article
Nutrition & Dietetics
Lucas Gosdin, Andrea J. Sharma, Katie Tripp, Esi Foriwa Amoaful, Abraham B. Mahama, Lilian Selenje, Maria Elena Jefferds, Reynaldo Martorell, Usha Ramakrishnan, O. Yaw Addo
Summary: School-based weekly IFA supplementation in Ghana has been shown to be effective in improving hemoglobin levels and reducing anemia prevalence among schoolgirls. However, most participants did not consume the minimum effective number of IFA tablets, indicating that increasing adherence to intake could further improve anemia outcomes in this population.
JOURNAL OF NUTRITION
(2021)
Article
Nutrition & Dietetics
Valerie M. Friesen, Mduduzi N. N. Mbuya, Frank T. Wieringa, Chito N. Nelson, Michael Ojo, Lynnette M. Neufeld
Summary: This article demonstrates the application of a decision-making framework for national food fortification programs, using the GRADE Evidence to Decision (EtD) framework. The framework classifies fortification program decisions into 5 types and involves a variety of decision makers, emphasizing the importance of using available evidence in the face of limited certainty.
CURRENT DEVELOPMENTS IN NUTRITION
(2022)
Article
Dentistry, Oral Surgery & Medicine
B. Turton, S. Sullivan, T. Chher, S. Hak, K. Sokal-Gutierrez, F. Wieringa, A. Singh
Summary: This study examines the relationship between dental caries and malnutrition in children. The results suggest that the development of pulpally involved carious lesions has an effect on wasting outcomes, but not on stunting. This highlights the importance of oral health promotion and preventive measures in low-income settings to promote normal growth and development among preschool children.
JOURNAL OF DENTAL RESEARCH
(2023)
Article
Nutrition & Dietetics
Valerie Greffeuille, Mamta Dass, Nadia Fanou-Fogny, Jolene Nyako, Jacques Berger, Frank T. T. Wieringa
Summary: This study estimated the coverage of micronutrient needs in standard diets for young children aged 6-24 months in Ghana and Benin, as well as the contributions of breastfeeding and nutrition programs. The results showed that standard diets only minimally contributed to micronutrient intake, while voluntary fortified complementary food played a significant role.
MATERNAL AND CHILD NUTRITION
(2023)
Editorial Material
Nutrition & Dietetics
Frank T. Wieringa, David I. Thurnham
JOURNAL OF NUTRITION
(2023)
Article
Nutrition & Dietetics
Jocelyne M. Labonte, Hou Kroeun, Sreang Sambo, Ngik Rem, Bohdan L. Luhovyy, Crystal D. Karakochuk, Tim J. Green, Frank T. Wieringa, Prak Sophonneary, Jeffrey R. Measelle, Dare Baldwin, Kyly C. Whitfield
Summary: Food taboos are food restrictions practiced by a group beyond individual preferences, which may lead to inadequate nutrition and poor health for mothers and infants. A study conducted in Cambodia found that 66% of women followed food taboos during the first 2 weeks postpartum, while about 20% restricted foods during other peripartum periods. The practices of food taboos varied greatly between women and were influenced by individual or household understandings of food and health during pregnancy and postpartum.
MATERNAL AND CHILD NUTRITION
(2023)
Article
Nutrition & Dietetics
Valerie M. Friesen, Jody C. Miller, Ryan B. Bitantes, Maria F. D. Reario, Charles D. Arnold, Mduduzi N. N. Mbuya, Lynnette M. Neufeld, Frank T. Wieringa, Ame Stormer, Mario V. Capanzana, Carl V. D. Cabanilla, Georg Lietz, Marjorie J. Haskell, Reina Engle-Stone
Summary: Comparing simplified questionnaire-based methods with 24-hour recalls (24HRs), we found that there were discrepancies in estimating fortifiable food consumption. The simplified methods, such as household food acquisition and purchase questionnaire (FAPQ) and 7-day semiquantitative food frequency questionnaire (SQ-FFQ), provided useful information but had limitations in accuracy and completeness.
MATERNAL AND CHILD NUTRITION
(2023)
Article
Soil Science
Ratha Muon, Chenda Lai, Vincent Herve, Rainer Zaiss, Francois Chassagne, Eve Bureau-Point, Sebastien Marchand, Martine Audibert, Jacques Berger, Frank Wieringa, Arnould Savoure, Kimchhin Sok, Jean-Dominique Meunier, Vannak Ann, Pascal Jouquet
Summary: This study quantified the density of termite mounds and their use by the local population in a catchment in Cambodia. The findings showed that the mounds were used for increasing soil fertility, cultivating crops, and consuming various animals, mushrooms, and plant species. The study also revealed the positive impact of mounds on farmers' health and pesticide reduction.
SOIL USE AND MANAGEMENT
(2023)
Article
Nutrition & Dietetics
Sanne Sigh, Nanna Roos, Chamnan Chhoun, Arnaud Laillou, Frank T. Wieringa
Summary: This study investigated the impact of ready-to-use therapeutic foods (RUTFs) on iron and vitamin A levels in children receiving treatment for severe acute malnutrition (SAM). The results showed that RUTFs had a limited effect on improving vitamin A and iron status, highlighting the need for further research on micronutrient bioavailability to enhance the effectiveness of SAM treatment.
Article
Nutrition & Dietetics
Sanne Sigh, Lotte Lauritzen, Frank T. Wieringa, Arnaud Laillou, Chhoun Chamnan, Ken D. Stark, Nanna Roos
Summary: This study aimed to investigate the change in whole-blood PUFA levels and nutrition and health markers among Cambodian children with severe acute malnutrition (SAM) after treatment with ready-to-use therapeutic foods (RUTFs). Results showed that RUTFs with fish-based ingredients had higher levels of n-3 PUFA, AA, and DHA, while milk-based RUTFs had higher levels of n-6 PUFA. The study found that the currently recommended composition of RUTFs may not be able to correct the compromised essential fatty acid status of children with SAM. Rating: 8/10
CLINICAL NUTRITION
(2023)
Review
Food Science & Technology
Dorgeles Kouakou Dje Kouadio, Frank Wieringa, Valerie Greffeuille, Christele Humblot
Summary: Micronutrient deficiencies or hidden hunger is a major public health problem, particularly in low- and middle-income countries, with significant impact on child development. Traditional methods of treatment and prevention have not always been effective and may have undesired side-effects. Gut microbiota, along with the gastrointestinal mucosa, plays a crucial role in enhancing the absorption of micronutrients and protecting against pathogens. However, the exact relationship between micronutrient malnutrition and gut microbiota is still poorly understood. This review provides current knowledge on the interaction between micronutrients and gut microbiota, specifically focusing on iron, zinc, vitamin A, and folate.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Article
Nutrition & Dietetics
Asrinisa Rachmadewi, Damayanti D. Soekarjo, Blandina Rosalina Bait, Julia Suryantan, Rivani Noor, Jee Hyun Rah, Frank T. Wieringa
Summary: In order to strengthen community-based treatment of severe acute malnutrition (SAM) in Indonesia, locally produced ready-to-use therapeutic foods (RUTFs) are needed. However, there is a lack of data on their acceptability and effectiveness. This study found that locally produced RUTFs were more acceptable to children in terms of consumption, and there was no significant difference in weight gain compared to the standard RUTF. The development of locally produced RUTFs in Indonesia is warranted to improve the community-based treatment of SAM.
Article
Nutrition & Dietetics
Iacopo Aiello, Sengchanh Kounnavong, Hari Vinathan, Khamseng Philavong, Chanthaly Luangphaxay, Somphone Soukhavong, Janneke Blomberg, Frank T. Wieringa
Summary: Malnutrition remains a public health problem in Lao PDR, with 9% of children under 5 being affected. A study found that culturally acceptable RUTFs, such as the locally produced mung bean RUTF, were the most preferred and accepted by caretakers. Therefore, promoting the use of mung bean RUTFs in Laos is recommended.
Retraction
Multidisciplinary Sciences
Thi-Phuong-Thao Pham, Maryam Tidjani Alou, Dipankar Bachar, Anthony Levasseur, Souleymane Brah, Daouda Alhousseini, Cheikh Sokhna, Aldiouma Diallo, Frank Wieringa, Matthieu Million, Didier Raoult
SCIENTIFIC REPORTS
(2023)
Article
Agronomy
Celia Mousties, Claire Bourlieu-Lacanal, Youna M. Hemery, Bruno Barea, Pierre Villeneuve, Adrien Servent, Pascaline Alter, Marc Lebrun, Arnaud Laillou, Frank T. Wieringa, Sylvie Avallone
Summary: The study showed that all RUTF products displayed good lipid stability, with only the European-manufactured one complying with international recommendations on vitamin A and E contents. One of the products made in Asia exceeded the regulatory limit of mycotoxins.
OCL-OILSEEDS AND FATS CROPS AND LIPIDS
(2022)