Review
Nutrition & Dietetics
Elzbieta Szczepanska, Agnieszka Bialek-Dratwa, Barbara Janota, Oskar Kowalski
Summary: Improper dietary behavior can influence the development of cardiovascular diseases, but certain food components can have cardioprotective effects. Polyphenols, most abundant in multicolored vegetables and fruits, have been shown to lower blood pressure, improve lipid profile, and regenerate vascular endothelium. Therefore, maintaining a varied diet can help prevent cardiovascular diseases.
Article
Biochemistry & Molecular Biology
Kanupriya Vashishth, Sumit K. Singh, Annish Jain, Alka Bhatia, Yash P. Sharma
Summary: This study aims to investigate the effects of excessive fructose intake on cardiovascular disease and metabolic syndrome. The results showed that rats consuming a high fructose diet had abnormal levels of diabetes, lipids, and inflammation in their hearts. The study also found a link between fructose intake and abnormal myocardial structure and increased levels of inflammatory markers.
JOURNAL OF FOOD BIOCHEMISTRY
(2022)
Article
Cardiac & Cardiovascular Systems
Yanan Liu, Mengke Li, Xue Lv, Kaiwen Bao, Xiao Yu Tian, Lei He, Lei Shi, Yi Zhu, Ding Ai
Summary: The study reveals that YAP protein is upregulated in metabolic syndrome and leads to the activation of the TGF beta pathway, resulting in arterial stiffness. It is found that YAP inhibits the dephosphorylation of Smads through removal of the ubiquitin chain. These findings are significant for the development of therapeutic targets for metabolic syndrome-associated arterial stiffness.
CIRCULATION RESEARCH
(2022)
Article
Nutrition & Dietetics
Yongbo She, Kun Wang, Alexander Makarowski, Rabban Mangat, Sue Tsai, Benjamin P. Willing, Spencer D. Proctor, Caroline Richard
Summary: This study investigated the impact of dairy and dairy fat on cardiometabolic risk factors and immune function using a low birthweight swine model. The results showed that consuming high-fat dairy products improved fasting plasma glucose concentrations compared to low-fat dairy, while dairy consumption had a neutral effect on fasting lipid profile. Furthermore, consuming low-fat dairy significantly improved the production of certain cytokines, indicating enhanced immune function.
FRONTIERS IN NUTRITION
(2022)
Article
Multidisciplinary Sciences
Yuanlong Hou, Wei Wei, Xiaojing Guan, Yali Liu, Gaorui Bian, Dandan He, Qilin Fan, Xiaoying Cai, Youying Zhang, Guangji Wang, Xiao Zheng, Haiping Hao
Summary: The study shows that dietary raffinose metabolism to fructose couples stress-induced gut microbial remodeling to intestinal stem cell renewal and epithelial homeostasis. Dietary impact on stress and gut microbial structure and epithelial integrity could be exploited to alleviate gut disorders. Dietary modulation of microbial metabolism shapes intestinal stem cell turnover, highlighting the interplay between diet, stress, and gut health.
NATURE COMMUNICATIONS
(2021)
Review
Medicine, General & Internal
Monica Aggarwal, Emilio Ros, Kathleen Allen, Geeta Sikand, Anandita Agarwala, Karen Aspry, Penny Kris-Etherton, Stephen Devries, Koushik Reddy, Tamanna Singh, Sheldon E. Litwin, James O' Keefe, Michael Miller, Bruce Andrus, Ron Blankstein, Columbus Batiste, Danielle Belardo, Christopher Wenger, Travis Batts, Neal D. Barnard, Beth A. White, Dean Ornish, Kim A. Williams, Robert J. Ostfeld, Andrew M. Freeman
Summary: The discussion of optimal dietary patterns for prevention and management of cardiovascular disease is limited in cardiology clinic visits. This article explores the benefits and risks of various dietary patterns within the context of cardiovascular disease to provide clinicians with necessary evidence and information for the maximum benefit of their patients.
AMERICAN JOURNAL OF MEDICINE
(2022)
Article
Biochemistry & Molecular Biology
Qixin Guo, Jingshan Cai, Qiang Qu, Iokfai Cheang, Jinjin Shi, Hui Pang, Xinli Li
Summary: This study aimed to investigate the association between trace elements and cardiovascular disease (CVD) and its types. The analysis of blood samples from 5101 participants revealed that higher selenium (Se) concentrations were negatively associated with overall CVD morbidity, while an increase in copper (Cu) concentrations was associated with an increased risk of stroke, heart failure, and heart attack. In addition, selenium and zinc were found to be negatively correlated with CVD prevalence.
BIOLOGICAL TRACE ELEMENT RESEARCH
(2023)
Article
Engineering, Chemical
Yen-Peng Lee, Chien-Chao Chiu, Yi-Hsun Chen, Wen-Ching Huang, Yu-Chih Wang, Ching-Feng Chiu, Tien-Jen Lin, Shao-Wen Hung, Ju-Yun Liu, Hsiao-Li Chuang
Summary: A high-fructose diet can lead to metabolic syndrome, gut microbial dysbiosis, obesity, and nonalcoholic fatty liver disease (NAFLD). This study found that a single cefotaxime treatment could partially modify gut bacterial composition and affect the severity of fructose-induced NAFLD. Analysis of the treatment groups revealed that only the CF-FD group showed symptoms of obesity and NAFLD.
Article
Food Science & Technology
Aline F. P. Souza, Juliana Woyames, Rosiane A. Miranda, Lorraine S. Oliveira, Bruna Caetano, Isabela L. Martins, Manuella S. Souza, Cherley B. Andrade, Thais Bento-Bernardes, Flavia F. Bloise, Rodrigo S. Fortunato, Isis H. Trevenzoli, Luana L. Souza, Carmen C. Pazos-Moura
Summary: This study investigates the effects of maternal high-fat diet on the liver mitochondrial responses to fructose intake in adult offspring. It found that moderate maternal high-fat diet can increase the intensity of liver mitochondrial alterations induced by fructose in offspring. The findings suggest that maternal diet can influence the risk of fructose damage in the liver of adult offspring.
MOLECULAR NUTRITION & FOOD RESEARCH
(2022)
Review
Nutrition & Dietetics
Pau Vancells Lujan, Esther Vinas Esmel, Emilio Sacanella Meseguer
Summary: NAFLD is the most common chronic liver disease worldwide, with its prevalence increasing in line with the global rise in diabetes and obesity. Currently, there is no effective pharmacotherapeutic treatment for NAFLD, so treatment is primarily based on lifestyle modifications such as diet and exercise. Unhealthy diets high in calories, sugars, and saturated fats, and low in polyunsaturated fatty acids, fiber, and micronutrients have been shown to play a critical role in the development and progression of NAFLD.
Article
Immunology
Rong Tan, Huiwei Dong, Zhengshan Chen, Min Jin, Jing Yin, Haibei Li, Danyang Shi, Yifan Shao, Huaran Wang, Tianjiao Chen, Dong Yang, Junwen Li
Summary: Unhealthy dietary habits are associated with increased incidence of chronic diseases, with high-fat and high-fructose diets leading to reduced defecation volume, increased levels of pro-inflammatory cytokines and IgG in serum, inflammatory cell infiltration in intestinal tissue, changes in microbial composition, alterations in microbial metabolites, and potential causes of constipation and inflammation.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Nuria Roglans, Elena Fauste, Roger Bentanachs, Ana M. Velazquez, Madelin Perez-Armas, Cristina Donis, Maria Panadero, Marta Alegret, Paola Otero, Carlos Bocos, Juan C. Laguna
Summary: In our study, we found that the HFHFr diet reduces the production of liver H2S, mainly by decreasing the expression of CBS and CSE. However, treatment with BemA restores H2S production by increasing the expression of CBS and CSE, suggesting the involvement of the FXR transcriptional activity and the mTORC1/S6K1/PGC1 alpha pathway.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Food Science & Technology
Che-Wei Lin, Chun-Hung Lin, Ya-Wen Hsu, Tzu-Ming Pan, Chun-Lin Lee
Summary: Monascin and ankaflavin from red mold Dioscorea can prevent type 2 diabetes and metabolic disorders induced by high fat and high fructose diet.
JOURNAL OF FUNCTIONAL FOODS
(2023)
Review
Nutrition & Dietetics
Emmanouil Mantzouranis, Eleftheria Kakargia, Fotis Kakargias, George Lazaros, Konstantinos Tsioufis
Summary: High protein diets have become popular for weight loss, muscle gain, and improved cardiometabolic parameters. However, few meta-analyses have examined their impact on cardiovascular morbidity and mortality, and have not found significant associations without strict definitions of high protein intake. This study found that high protein consumption does not affect cardiovascular prognosis.
Article
Cell Biology
Milton D. Chiang Morales, Chao-Yuan Chang, Van Long Le, I-Tao Huang, I-Lin Tsai, Hung-Jen Shih, Chun-Jen Huang
Summary: This study utilized a proteomic approach to investigate the impact of high-fructose plus high-fat diet (HFr/HFD) and high-fat diet (HFD) on liver injury in murine models. The results showed that the hepatic mitochondrial oxidative phosphorylation pathway was significantly downregulated in the HFr/HFD group compared to the HFD group, with alterations in protein levels of specific complexes within the pathway.
Article
Nutrition & Dietetics
Yeji Kang, Namhee Kim, Yong Jun Choi, Yunhwan Lee, Jihye Yun, Seok Jun Park, Hyoung Su Park, Yoon-Sok Chung, Yoo Kyoung Park
Article
Medicine, General & Internal
Sun Min Lee, Hong-sun Song, Buong-O Chun, Muncheong Choi, Kyunghwa Sun, Ki Sub Kim, Hyesu Jeon, Da Eun Seo, Hye Mi Kwon, Jee Hyang Jeong, Yoo Kyoung Park, Chang Hyung Hong, Hae Ri Na, Seong Hye Choi, So Young Moon
JOURNAL OF CLINICAL MEDICINE
(2020)
Article
Food Science & Technology
Yong-Seok Kwon, Jihye Ryu, Yuyeong Yang, Yoo-Kyoung Park, Sohye Kim
Review
Nutrition & Dietetics
Hyejin Ahn, Yoo Kyoung Park
Summary: This study conducted a systematic review and meta-analysis, revealing a significant inverse association between sugar-sweetened beverages (SSBs) intake and bone mineral density (BMD) in adults. Subgroup analyses showed significant effects on whole body BMD, female BMD, and BMD in individuals aged under 50 years.
Article
Food Science & Technology
Hosun Lee, Mihyang Um, Kisun Nam, Sang-Jin Chung, Yookyoung Park
Summary: The study aimed to investigate glycemic response after consuming ready-to-eat meals and develop a GL prediction formula using nutrient composition. The formula can be a useful tool for estimating GL after consuming such meals, providing guidance for blood sugar management.
Article
Food Science & Technology
Hyejin Ahn, Miran Lee, Hyeri Shin, Heajung-Angie Chung, Yoo-Kyoung Park
Summary: This study evaluates whether blood glucose response differs upon consuming rice cooked in a carbohydrate-reducing rice cooker. The results suggest that low-carb rice may have potential health benefits in reducing early postprandial spikes in blood glucose level.
Article
Nutrition & Dietetics
Ji-hyun Lee, Mihyang Kim, Donghwan Choi, Junsik Kwon, Yoo Kyoung Park
Summary: This study evaluated the adequacy of nutritional supply and its correlation with clinical outcomes. Results showed that the energy and protein provided were insufficient compared to recommendations. The isocaloric group had a shorter duration of ventilator use compared to the hypocaloric group.
NUTRITION & DIETETICS
(2023)
Article
Nutrition & Dietetics
Yongseok Kwon, Kyung Hee Hong, Yoo-Kyung Park, Sohye Kim
Summary: This study examined the relationship between general population characteristics and diet-related factors pertaining to eating alone for older adults (65 years and older) in Korea. The study used data from the Korea National Health and Nutrition Examination Survey (KNHANES), 2016-2020, focusing on 7037 Koreans aged 65 years or older who participated in the survey. The main findings suggest that higher frequency of eating alone is associated with lower food security, essential food intake, and quality of life. Based on these results, implementing a dietary life support program such as eating together program is necessary to improve the quality of life of older individuals who eat alone.
Article
Nutrition & Dietetics
Hye-Ri Shin, Young-Sun Kim, Yoo-Kyung Park, Seul-Ki Koo, Woo-Hyun Son, Jae-Won Han, Eun-Ha Son, Hae-Jin Kang, Kyeong-Hee Choi, Jin-Soo Han, Hyun-Sun Lee, Hee-Sook Lim
Summary: Considering Korea's aging population, this study evaluated the impact of a senior-friendly diet on the nutrition and health status of older adults receiving community care. The intervention group showed significant improvements in energy, protein, and vitamin intake, as well as frailty levels and malnutrition rates. Resolving meals based on the physiological needs of older adults is crucial for improving their quality of life in a super-aged society.
Article
Neurosciences
Hyun Jeong Yoon, Woorim Kang, Sungyang Jo, Yun Su Hwang, Je Hee Lee, Sun Ju Chung, Yoo Kyoung Park
Summary: This study investigated the differences in dietary intake and quality between Parkinson's disease (PD) patients and controls, and found that the gut microbiome composition differed between the two groups. However, there were no significant differences in dietary intake between the groups.
NUTRITIONAL NEUROSCIENCE
(2023)
Article
Nutrition & Dietetics
Dahyun Park, Mi-Kyung Choi, Yoo Kyoung Park, Clara Yongjoo Park, Min-Jeong Shin
Summary: Most existing food literacy measurement tools for children and adolescents focus on nutrition and food safety, but fail to include aspects related to the food system, such as food distribution and food waste, and their impact on environmental sustainability. This study developed and validated a two-dimensional tool to comprehensively measure food literacy in children and adolescents, and found a positive association between food literacy, diet quality, and self-reported health.
NUTRITION RESEARCH AND PRACTICE
(2022)
Article
Nutrition & Dietetics
Dahyun Park, Yoo Kyoung Park, Clara Yongjoo Park, Mi-Kyung Choi, Min-Jeong Shin
Article
Nutrition & Dietetics
Yong-Suk Kwon, Yu-Yeong Yang, Younghee Park, Yoo-Kyoung Park, Sohye Kim
Article
Clinical Neurology
Hee Kyung Park, Jee Hyang Jeong, So Young Moon, Yoo Kyoung Park, Chang Hyung Hong, Hae Ri Na, Hong-Sun Song, Sun Min Lee, Muncheong Choi, Kyung Won Park, Byeong C. Kim, Soo Hyun Cho, Buong-O Chun, Seong Hye Choi
JOURNAL OF CLINICAL NEUROLOGY
(2020)
Article
Nutrition & Dietetics
Kyung Ah Lee, Jung-Chul Park, Yoo Kyoung Park
NUTRITION RESEARCH AND PRACTICE
(2020)