4.7 Article

Association between Toenail Mercury and Metabolic Syndrome Is Modified by Selenium

期刊

NUTRIENTS
卷 8, 期 7, 页码 -

出版社

MDPI
DOI: 10.3390/nu8070424

关键词

toenail mercury; metabolic syndrome; effect-modification; selenium; Asian

资金

  1. Basic Science Research Program through the National Research Foundation of Korea (NRF) - Ministry of Science, ICT & Future Planning [NRF-2014R1A1A3049866]
  2. National Research Foundation of Korea [2014R1A1A3049866] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)

向作者/读者索取更多资源

Background: Although Asian populations consume relatively large amounts of fish and seafood and have a high prevalence of metabolic diseases, few studies have investigated the association between chronic mercury exposure and metabolic syndrome and its effect modification by selenium. Methods: We analyzed baseline data from the Trace Element Study of Korean Adults in the Yeungnam area. Participants included 232 men and 269 women, aged 35 years or older, who had complete data regarding demographic, lifestyle, diet, toenail mercury and selenium levels, and health. Toenail mercury and selenium concentrations were measured using instrumental neutron-activation analysis. The metabolic biomarker levels were obtained through biannual medical checkups. Results: Higher toenail mercury levels were associated with habitual consumption of whale and shark meats, older age, obesity, smoking, alcohol drinking, and higher household income. Multivariable analysis showed a positive association between toenail mercury exposure and metabolic syndrome. In addition, this association was significantly stronger at lower selenium levels and was weaker at higher selenium levels. Conclusion: The possible harmful effects of mercury on metabolic syndrome may be attenuated by high levels of selenium. Future studies are needed to suggest optimal dietary guidelines regarding fish and selenium intakes, particularly for Asians with high levels of fish intake.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.7
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

Article Biochemistry & Molecular Biology

Toenail mercury levels positively correlate with obesity and abdominal obesity among Korean adults

Jimin Jeon, J. Steven Morris, Kyong Park

Summary: This study examined the association between chronic mercury exposure and obesity in Korean adults. The findings showed a linear relationship between increased toenail mercury levels and higher prevalence of obesity and abdominal obesity. Public health interventions against environmental exposure of foods are needed to manage and prevent obesity.

JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY (2021)

Article Nutrition & Dietetics

Higher Branched-Chain Amino Acid Intake Is Associated with Handgrip Strength among Korean Older Adults

Seonghee Park, Minjeong Chae, Hyoungsu Park, Kyong Park

Summary: The study aimed to investigate the association between BCAA intake and handgrip strength in Korean older adults, finding a positive correlation between leucine intake and handgrip strength, which is beneficial for maintaining muscle health.

NUTRIENTS (2021)

Article Nutrition & Dietetics

Association between Soy Food and Dietary Soy Isoflavone Intake and the Risk of Cardiovascular Disease in Women: A Prospective Cohort Study in Korea

Jihyun Im, Kyong Park

Summary: This study found that the intake of highest amounts of tofu, total soy foods, and dietary soy isoflavones is significantly associated with a decreased risk of cardiovascular disease in premenopausal Korean women, while no association was observed in postmenopausal women.

NUTRIENTS (2021)

Article Psychiatry

Association between the level of adherence to dietary guidelines and depression among Korean patients with type 2 diabetes mellitus

Seonghee Park, Kyong Park

Summary: The study found that T2DM patients with lower adherence to dietary guidelines were more likely to report depression. Patients with poor adherence to moderate calorie consumption and regular meal patterns were more likely to report depression. However, patients with poor adherence to low sodium intake were less likely to report depression.

JOURNAL OF PSYCHOSOMATIC RESEARCH (2021)

Article Biochemistry & Molecular Biology

Association between Phytochemical Index and Inflammation in Korean Adults

Chaehyun Kim, Kyong Park

Summary: This study evaluated the association between phytochemical index (PI) and inflammation levels in Korean adults. The results showed that a high consumption of phytochemical-rich foods is associated with lower inflammation. Therefore, adopting a phytochemical-rich dietary pattern may be an effective approach for reducing inflammation.

ANTIOXIDANTS (2022)

Article Nutrition & Dietetics

Phytochemical index and hypertension in Korean adults using data from the Korea National Health and Nutrition Examination Survey in 2008-2019

Unhui Jo, Kyong Park

Summary: This study examined the association between phytochemical levels and hypertension in Korean adults and found that consumption of phytochemical-rich foods may lower the prevalence of hypertension.

EUROPEAN JOURNAL OF CLINICAL NUTRITION (2022)

Article Nutrition & Dietetics

Dietary Essential Amino Acid Intake Is Associated with High Muscle Strength in Korean Older Adults

Jihyun Im, Hyoungsu Park, Kyong Park

Summary: This population-based study in Korean older adults found that a high intake of essential amino acids (EAAs), especially from animal sources, was associated with increased muscle strength. The study highlights the importance of consuming an adequate amount of EAAs from various food sources to achieve high muscle strength.

NUTRIENTS (2022)

Article Nutrition & Dietetics

Dietary niacin intake and risk of dyslipidemia: A pooled analysis of three prospective cohort studies

Chaehyun Kim, Kyong Park

Summary: This study found that higher dietary niacin intake was associated with a reduced risk of dyslipidemia. Compared to the group with dietary niacin intake above the recommended level in Korea, the risk of dyslipidemia increased by 32% in the group below the estimated average requirement in Korea. The results suggest that consuming foods with high niacin levels may help prevent or delay the onset of dyslipidemia.

CLINICAL NUTRITION (2022)

Article Nutrition & Dietetics

Higher Intake of Total Dietary Essential Amino Acids Is Associated with a Lower Prevalence of Metabolic Syndrome among Korean Adults

Jihyun Im, Hyoungsu Park, Kyong Park

Summary: This study found that a well-balanced intake of total essential amino acids (EAAs) is associated with a lower prevalence of metabolic syndrome among Korean adults. When the overall EAA intake meets the recommended nutrient intake, the risk of high blood pressure, hypertriglyceridemia, and metabolic syndrome can be reduced.

NUTRIENTS (2022)

Article Biochemistry & Molecular Biology

Sugar-Sweetened Coffee Intake and Blood Glucose Management in Korean Patients with Diabetes Mellitus

Hyeonji Yoo, Kyong Park

Summary: This study examined the impact of sugar-sweetened coffee consumption on blood sugar levels in patients with diabetes mellitus. The results showed that frequent consumption of sugar-sweetened coffee was associated with higher blood glucose levels and difficulty in glycemic control.

METABOLITES (2022)

Editorial Material Nutrition & Dietetics

The Role of Dietary Phytochemicals: Evidence from Epidemiological Studies

Kyong Park

NUTRIENTS (2023)

Article Nutrition & Dietetics

Association between Phytochemical Index and Osteoporosis in Women: A Prospective Cohort Study in Korea

Hyeonji Yoo, Kyong Park

Summary: This study examined the relationship between phytochemical-rich food intake and osteoporosis incidence in premenopausal and postmenopausal women. It found that postmenopausal women with the highest intake of phytochemical-rich foods had a 16% lower risk of osteoporosis. No significant association was observed among premenopausal women. These findings suggest that consuming phytochemical-rich foods may offer protection against osteoporosis in postmenopausal women.

NUTRIENTS (2023)

Review Nutrition & Dietetics

Carbohydrate Intake and Risk of Cardiovascular Disease: A Systematic Review and Meta-Analysis of Prospective Studies

Unhui Jo, Kyong Park

Summary: The purpose of this study was to summarize the conflicting results from previous studies on the association between carbohydrate intake and cardiovascular disease (CVD) using a systematic review and meta-analysis. The meta-analysis revealed that individuals with the highest carbohydrate intake had a 1.15-fold increased risk of CVD compared to those with the lowest intake. Subgroup analysis showed that this association was only present in Asia, with a 1.52-fold increased risk, while no associations were seen in the Americas, Europe, and Oceania. This study suggests that a high-carbohydrate diet may raise the risk of CVD, particularly in Asian populations.

NUTRIENTS (2023)

Article Nutrition & Dietetics

Association between dietary omega-3 fatty acid intake and depression in postmenopausal women

Minjeong Chae, Kyong Park

Summary: The study found an inverse relationship between dietary omega-3 fatty acid intake and depression in postmenopausal women in a dose-response manner. Further large cohort studies are needed to confirm the causality between omega-3 fatty acids and depression in Korean postmenopausal women.

NUTRITION RESEARCH AND PRACTICE (2021)

Article Nutrition & Dietetics

Association between dietary branched-chain amino acid intake and skeletal muscle mass index among Korean adults: Interaction with obesity

Minjeong Chae, Hyoung Su Park, Kyong Park

Summary: This study examined the association between dietary intake levels of BCAA and skeletal muscle mass index (SMI) in middle-aged participants, finding that the beneficial effects of BCAA intake on SMI were greater in non-obesity/non-abdominal obesity groups. No significant associations were observed in obesity/abdominal obesity groups. Maintaining a healthy weight and consuming sufficient dietary BCAA are recommended to preserve muscle mass.

NUTRITION RESEARCH AND PRACTICE (2021)

暂无数据