The role of break-induced replication in large-scale expansions of (CAG) n /(CTG) n repeats

Replication stalling and heteroduplex formation within CAG/CTG trinucleotide repeats by mismatch repair

(2016) David Viterbo et al.   DNA REPAIR

Disease-associated repeat instability and mismatch repair

(2016) Monika H.M. Schmidt et al.   DNA REPAIR

Regulation of recombination at yeast nuclear pores controls repair and triplet repeat stability

(2015) Xiaofeng A. Su et al.   GENES & DEVELOPMENT

Translesion Polymerases Drive Microhomology-Mediated Break-Induced Replication Leading to Complex Chromosomal Rearrangements

(2015) Cynthia J. Sakofsky et al.   MOLECULAR CELL

Mus81 and converging forks limit the mutagenicity of replication fork breakage

(2015) R. Mayle et al.   SCIENCE

Large expansion of CTG•CAG repeats is exacerbated by MutSβ in human cells

(2015) Rie Nakatani et al.   Scientific Reports

Mechanisms and Regulation of Mitotic Recombination in Saccharomyces cerevisiae

(2014) L. S. Symington et al.   GENETICS

Myotonic Dystrophy

(2014) Charles A. Thornton   NEUROLOGIC CLINICS

Coupling Transcriptional State to Large-Scale Repeat Expansions in Yeast

(2014) Kartik A. Shah et al.   Cell Reports

The balancing act of DNA repeat expansions

(2013) Jane C Kim et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Nucleotide excision repair and the 26S proteasome function together to promote trinucleotide repeat expansions

(2013) Claire Concannon et al.   DNA REPAIR

Pif1 helicase and Polδ promote recombination-coupled DNA synthesis via bubble migration

(2013) Marenda A. Wilson et al.   NATURE

Friedreich's ataxia–associated GAA repeats induce replication-fork reversal and unusual molecular junctions

(2013) Cindy Follonier et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Dynamics of yeast histone H2A and H2B phosphorylation in response to a double-strand break

(2013) Cheng-Sheng Lee et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Genome rearrangements caused by interstitial telomeric sequences in yeast

(2013) A. Y. Aksenova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Break-Induced DNA Replication

(2013) R. P. Anand et al.   Cold Spring Harbor Perspectives in Biology

High levels of somatic DNA diversity at the myotonic dystrophy type 1 locus are driven by ultra-frequent expansion and contraction mutations

(2012) Catherine F. Higham et al.   HUMAN MOLECULAR GENETICS

Altered Replication in Human Cells Promotes DMPK (CTG)n {middle dot} (CAG)n Repeat Instability

(2012) G. Liu et al.   MOLECULAR AND CELLULAR BIOLOGY

DNA base excision repair: a mechanism of trinucleotide repeat expansion

(2012) Yuan Liu et al.   TRENDS IN BIOCHEMICAL SCIENCES

Role of DNA Polymerases in Repeat-Mediated Genome Instability

(2012) Kartik A. Shah et al.   Cell Reports

Msh2-Msh3 Interferes with Okazaki Fragment Processing to Promote Trinucleotide Repeat Expansions

(2012) Athena Kantartzis et al.   Cell Reports

Histone Deacetylase Complexes Promote Trinucleotide Repeat Expansions

(2012) Kim Debacker et al.   PLOS BIOLOGY

Expansions, contractions, and fragility of the spinocerebellar ataxia type 10 pentanucleotide repeat in yeast

(2011) N. Cherng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Break-Induced Replication Is Highly Inaccurate

(2011) Angela Deem et al.   PLOS BIOLOGY

Defining Genetic Factors That Modulate Intergenerational CAG Repeat Instability in Drosophila melanogaster

(2010) J. Jung et al.   GENETICS

Replication-dependent instability at (CTG)•(CAG) repeat hairpins in human cells

(2010) Guoqi Liu et al.   Nature Chemical Biology

Mechanisms of trinucleotide repeat instability during human development

(2010) Cynthia T. McMurray   NATURE REVIEWS GENETICS

Repeat expansion disease: progress and puzzles in disease pathogenesis

(2010) Albert R. La Spada et al.   NATURE REVIEWS GENETICS

Systematic identification of fragile sites via genome-wide location analysis of γ-H2AX

(2010) Rachel K Szilard et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Continuous and Periodic Expansion of CAG Repeats in Huntington's Disease R6/1 Mice

(2010) Linda Møllersen et al.   PLoS Genetics

Double-Strand Break Repair Pathways Protect against CAG/CTG Repeat Expansions, Contractions and Repeat-Mediated Chromosomal Fragility in Saccharomyces cerevisiae

(2009) R. Sundararajan et al.   GENETICS

Large-Scale Expansions of Friedreich's Ataxia GAA Repeats in Yeast

(2009) Alexander A. Shishkin et al.   MOLECULAR CELL

SRS2 and SGS1 prevent chromosomal breaks and stabilize triplet repeats by restraining recombination

(2009) Alix Kerrest et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A Microhomology-Mediated Break-Induced Replication Model for the Origin of Human Copy Number Variation

(2009) P. J. Hastings et al.   PLoS Genetics

Chromosome fragility at GAA tracts in yeast depends on repeat orientation and requires mismatch repair

(2008) Hyun-Min Kim et al.   EMBO JOURNAL

Segmental Duplications Arise from Pol32-Dependent Repair of Broken Forks through Two Alternative Replication-Based Mechanisms

(2008) Celia Payen et al.   PLoS Genetics