Article
Oncology
Kai Wu, Liuhong Shi, Jianbiao Wang, Lei Xie
Summary: The aim of this study was to evaluate the association between coexisting lymphocytic thyroiditis (LT) and the clinicopathological features of papillary thyroid carcinoma (PTC). The records of 458 patients with PTC were analyzed, and the prevalence of coexisting LT was found to be 29.0%. PTC concomitant with LT was significantly associated with female patients, lower extrathyroidal extension, larger metastatic lymph nodes, and higher occurrence of multifocality.
Article
Multidisciplinary Sciences
Bahri Evren, Sami Yilmaz, Nese Karadag, Ayse Cikim Sertkaya, Omercan Topaloglu, Faruk Kilinc
Summary: The study aimed to quantitatively evaluate DNA repair protein levels in patients with malignant thyroid lesions, showing differences in follicular cell positivity between papillary carcinoma and colloidal goiter. Further studies are needed to explore the potential role of DNA repair proteins in thyroid cancer development and progression.
SCIENTIFIC REPORTS
(2021)
Article
Endocrinology & Metabolism
Davut Sakiz, Muhammed Erkam Sencar, Murat Calapkulu, Ilknur Ozturk Unsal, Levent Aktas, Bekir Ucan, Mustafa Ozbek, Erman Cakal
Summary: This study evaluated the impact of chronic lymphocytic thyroiditis (CLT) on clinicopathologic parameters, prognostic outcome, and initial treatment responses in patients with papillary thyroid cancer (PTC). The results showed that the coexistence of PTC and CLT is very frequent, with patients diagnosed at a younger age and higher thyroid-stimulating hormone levels. However, no positive effect of the CLT and PTC combination on clinicopathologic factors was detected, and lymphovascular and perineural invasions were more common in the group with CLT.
ENDOCRINE PRACTICE
(2021)
Article
Oncology
Weibin Wang, Liping Wen, Shitu Chen, Xingyun Su, Zhuochao Mao, Yongfeng Ding, Zhendong Chen, Yiran Chen, Jiaying Ruan, Jun Yang, Jie Zhou, Xiaodong Teng, Thomas J. Fahey, Zhongqi Li, Lisong Teng
Summary: Thyroid autoimmunity is not a protective factor in patients with papillary thyroid carcinoma (PTC), while preoperative TPOAb levels can predict the recurrence of papillary thyroid carcinoma.
FRONTIERS IN ONCOLOGY
(2022)
Article
Endocrinology & Metabolism
Ping Xing, Hua-Rong Luo, Cheng Xu, Yong Liang, Feilin Cao
Summary: This study found that PTC + HT patients have lower levels of immune-related factors and lower lymph node metastasis rates. There are differences in immune cell infiltration levels between PTC patients and PTC+HT patients.
JOURNAL OF BIOLOGICAL REGULATORS AND HOMEOSTATIC AGENTS
(2023)
Article
Endocrinology & Metabolism
Yang Liu, Hongjun Lv, Shaoqiang Zhang, Bingyin Shi, Yushi Sun
Summary: The study found that HT combined with PTC is more common in women, and the TSH level in the HT group is higher than in patients with PTC alone. Predictive factors for CLNM in PTC patients include male gender, age <= 45 years old, tumor diameter >1 cm, and presence of suspicious central compartment lymph node on US.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Oncology
Xiao-xiong Gan, Ya-yi Li, Si-jin Li, Shi-sen Mo, Jian-hua Feng, Fei Shen, Wen-song Cai, Ye-qian Lai, Bo Xu
Summary: Papillary thyroid carcinoma (PTC) concurrent with Hashimoto's thyroiditis (HT) is associated with better clinical prognosis. DMBT1 may act as a potential factor inhibiting tumors, and its high expression could improve PTC prognosis through immune-related pathways.
FRONTIERS IN ONCOLOGY
(2021)
Article
Surgery
Junhao Ma, Zhuochao Mao, Yunjin Yao, Yimin Lu, Haohao Wang, Yan Yang, Jun Yang, Weibin Wang, Lisong Teng
Summary: The study evaluated the prevalence and tumor characteristics of PTC in patients with SHPT. The results showed that compared to the general population, most papillary thyroid carcinomas with SHPT are occult and present no significant differences in tumor pathological features and prognostic staging.
Article
Oncology
Jean-Nicolas Gallant, Vivian L. Weiss, Sheau-Chiann Chen, Jiancong Liang, Ryan H. Belcher, Fei Ye, Hernan Correa, Huiying Wang
Summary: This study found an association between pediatric thyroid cancer and HT, although this association does not seem to affect patient outcomes or survival.
Article
Endocrinology & Metabolism
Yoon Young Cho, Yun Jae Chung, Hee Sung Kim
Summary: The study aimed to assess the malignancy risk of AUS/FLUS thyroid nodules, and found that the malignancy rate of thyroid nodules with AUS/FLUS cytology was comparable irrespective of the presence of underlying CLT.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Yi Li, Yue Zang, Tianda Fan, Zhaochen Li, Anzi Li, Wei Lv, Qingqing Wang, Qinglan Li, Yuanyuan Li, Quan Li, Zhongsheng Sun, Huajing Teng
Summary: This study reveals shared molecular signatures underlying thyroid dysfunction between patients receiving anti-PD-1/PD-L1 inhibitors and PTC patients suffering from Hashimoto thyroiditis, which may provide insights into managing adverse events during cancer immunotherapy.
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL
(2022)
Review
Multidisciplinary Sciences
Yang yang Guan
Summary: The immune dysfunction caused by HIV infection can lead to autoimmune-related diseases including hyperthyroidism. Hyperthyroidism can be primary or secondary. Graves' disease, the most common form of primary hyperthyroidism, may occur in HIV patients during immune reconstitution after antiretroviral therapy. This case describes a 47-year-old woman with HIV who presented with hyperthyroidism symptoms and was eventually diagnosed with papillary thyroid carcinoma after failed drug therapy and opting for surgical treatment.
Article
Oncology
Daichi Murakami, Masayoshi Hijiya, Takuro Iyo, Sachiko Hayata, Takashi Ozaki, Keisuke Enomoto, Masamitsu Kono, Shunji Tamagawa, Muneki Hotomi
Summary: Turner syndrome patients with chronic thyroiditis are more prone to develop thyroid malignancies. This case report describes a rare occurrence of solid variant papillary thyroid carcinoma in a 22-year-old female with Turner syndrome and chronic thyroiditis. No genetic mutations related to the cancer were detected in the patient's gene panel test.
FRONTIERS IN ONCOLOGY
(2023)
Review
Endocrinology & Metabolism
Lukasz Janicki, Agastya Patel, Jaroslaw Jendrzejewski, Andrzej Hellmann
Summary: This meta-analysis reveals that the prevalence of BRAF mutation is lower in patients with PTC-HT compared to conventional PTC, which may explain the indolent clinicopathological course in this cohort.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Medicine, General & Internal
Yi-Ting Liu, Jing Wang, Yan-Xia Sui, Dong-Li Zhao
Summary: This is a rare case of coexistence of epithelioid angiosarcoma (EA) in the left submandibular gland and papillary thyroid carcinoma (PTC) in the left thyroid gland. Precise preoperative diagnosis was challenging due to the coexistence of EA and PTC. Surgery and radiotherapy were effective treatments for this coexistence of EA and PTC.
Article
Gastroenterology & Hepatology
Michele Schiano di Visconte, Francesco Nicoli, Roberto Del Giudice, Tommaso Cipolat Mis
INTERNATIONAL JOURNAL OF COLORECTAL DISEASE
(2017)
Article
Surgery
C. Dobrinja, M. Troian, T. Cipolat Mis, G. Rebez, S. Bernardi, B. Fabris, L. Piscopello, P. Makovac, F. Di Gregorio, N. de Manzini
INTERNATIONAL JOURNAL OF SURGERY
(2017)
Article
Surgery
Gabriele Bellio, Tommaso Cipolat, Roberto Del Giudice, Gabriele Munegato
SURGICAL INNOVATION
(2019)
Article
Gastroenterology & Hepatology
Michele Schiano di Visconte, Arianna Pasquali, Tommaso Cipolat Mis, Luigi Brusciano, Ludovico Docimo, Gabriele Bellio
INTERNATIONAL JOURNAL OF COLORECTAL DISEASE
(2019)
Article
Surgery
Laura Bonadio, Cristiana Iacuzzo, Davide Cosola, Tommaso Cipolat Mis, Fabiola Giudici, Biagio Casagranda, Alan Biloslavo, Nicolo de Manzini
UPDATES IN SURGERY
(2020)
Letter
Gastroenterology & Hepatology
L. Bernardi, T. Cipolat Mis, M. Troian, N. de Manzini
COLORECTAL DISEASE
(2020)
Article
Surgery
Cristiana Iacuzzo, Paola Germani, Marina Troian, Tommaso Cipolat Mis, Fabiola Giudici, Edoardo Osenda, Marina Bortul, Nicolo de Manzini
Summary: This study confirmed the prognostic role of pre-operative serum CEA level in predicting overall survival and risk of recurrence in colorectal cancer patients. Optimal CEA cut-off values were identified to stratify patients into low, moderate, and high risk classes, providing valuable information for personalized therapy and risk stratification.
ANZ JOURNAL OF SURGERY
(2021)
Letter
Gastroenterology & Hepatology
L. Bernardi, T. Cipolat Mis, M. Troian, N. de Manzini
COLORECTAL DISEASE
(2020)