Article
Multidisciplinary Sciences
Shixie Jiang, Jingyu Huang, Hao Yang, Ryan Wagoner, F. Andrew Kozel, Glenn Currier, Huabei Jiang
Summary: This study utilized a novel diffuse optical tomography (DOT) device to investigate the neurophysiological effects of rTMS in depressed and healthy subjects. The results demonstrated that depressed subjects had a delayed and less robust response to rTMS with decreased volume of activation compared to healthy subjects.
SCIENTIFIC REPORTS
(2021)
Article
Biochemistry & Molecular Biology
Amandine Robac, Pauline Neveu, Alizee Hugede, Elisabeth Garrido, Lionel Nicol, Quentin Delarue, Nicolas Guerout
Summary: The study demonstrates that repetitive trans-spinal magnetic stimulation (rTSMS) can modulate lesion scar and induce functional locomotor recovery after spinal cord injury (SCI) in rats. rTSMS decreases formation of cystic cavities and improves axonal survival in both SCI models, showing promising effects for potential use in human treatment.
Article
Clinical Neurology
Syusaku Sasada, Suguru Kadowaki, Toshiki Tazoe, Takashi Murayama, Kenji Kato, Yaoki Nakao, Hideyuki Matsumoto, Yukio Nishimura, Yoshikazu Ugawa
Summary: The study aimed to assess safety issues of self-controlled repetitive trans-vertebral magnetic stimulation (rTVMS) in humans and found no serious adverse events in any participants. The results indicate that rTVMS can be used safely in physiological investigations in healthy volunteers and as treatment for neurological disorders.
CLINICAL NEUROPHYSIOLOGY
(2021)
Article
Clinical Neurology
Takao Mitsui, Yoshiharu Arii, Koichiro Taniguchi, Satoshi Tsutsumi, Mika Takahara, Masaru Mabuchi, Nichika Sumitomo, Mieko Matsuura, Yukiko Kuroda
Summary: This study evaluated the effect of repetitive trans-spinal magnetic stimulation (rTSMS) on patients with Parkinson's disease (PD). The results showed that rTSMS promotes the effect of rehabilitation on motor function in patients with PD.
Article
Psychiatry
Ronald E. See, Branon Eusebio, David Agnew, Mark Heatwole
Summary: The study found that steroid hormones may not be reliable biomarkers of treatment response in patients with major depressive disorder undergoing repetitive transcranial magnetic stimulation (rTMS). While rTMS significantly improved symptoms, salivary biomarker levels did not show significant changes during the treatment sessions.
PSYCHIATRY RESEARCH
(2021)
Article
Medicine, General & Internal
Xin Li, Guang-fu Song, Jia-nan Yu, Si-hui Ai, Qing Ji, Ying Peng, Xiao-feng Zhu, Ji-guang Liu
Summary: The study aimed to investigate the effectiveness and safety of repetitive transcranial magnetic stimulation (rTMS) on patients with morphine dependence (MD). Results showed that the rTMS group had better improvement in morphine craving intensity, depression, anxiety, and sleep quality compared to the control group. No treatment-related adverse events were identified in both groups.
Article
Neurosciences
Melina Engelhardt, Jana Kimmel, Giovanni Raffa, Alfredo Conti, Thomas Picht
Summary: The study demonstrates that accelerated low-frequency rTMS is a safe and feasible method for stimulating the motor cortex, and may make rTMS protocols more accessible to patients.
FRONTIERS IN NEUROSCIENCE
(2022)
Review
Immunology
Yi-Wen Bai, Qi-Hao Yang, Pei-Jie Chen, Xue-Qiang Wang
Summary: Neuropathic pain is a common condition caused by damage or disease to the nervous system, and is associated with excessive inflammation. Repetitive transcranial magnetic stimulation (rTMS) is an adjunctive treatment for neuropathic pain, which can regulate the neuroinflammation system to produce analgesic effects.
FRONTIERS IN IMMUNOLOGY
(2023)
Review
Psychiatry
Gerasimos N. Konstantinou, Alisson P. Trevizol, Jonathan Downar, Shelley F. McMain, Fidel Vila-Rodriguez, Zafiris J. Daskalakis, M. Blumberger
Summary: The literature on the application of repetitive transcranial magnetic stimulation (rTMS) in Borderline Personality Disorder (BPD) is unclear, but existing studies suggest that rTMS is a well-tolerated treatment in patients with BPD. Further research is needed to determine the efficacy of rTMS in different symptoms of BPD and to establish the best cortical targets and stimulation protocols. Longitudinal studies combining evidence-based psychotherapy with rTMS may be a promising approach to improve outcomes for this population in the future.
PSYCHIATRY RESEARCH
(2021)
Review
Neurosciences
Nabila Brihmat, Didier Allexandre, Soha Saleh, Jian Zhong, Guang H. Yue, Gail F. Forrest
Summary: There is a growing interest in using non-invasive stimulation interventions, such as repetitive transcranial magnetic stimulation (rTMS), to improve functional outcomes and recovery after spinal cord injury (SCI). This scoping review focuses on the stimulation parameters used in 20 rTMS protocols and explores their potential associations with observed effects. Future studies should consider timing, intervention duration, and dosage in relation to the stage, level, and severity of the injury. More real vs. sham rTMS studies with similar designs and replication information are needed to establish a significant level of evidence for the use of rTMS in SCI.
FRONTIERS IN HUMAN NEUROSCIENCE
(2022)
Article
Clinical Neurology
Patrick A. Massey, Stephen Hoge, Bradley G. Nelson, Alan L. Ogden, Milan G. Mody, Mitchell Myers, Karl Bilderback, Giovanni Solitro, Richard S. Barton
Summary: The study compared the biomechanical performance of nitinol memory metal rods and titanium rods as posterior spinal instrumentation in a synthetic model. It found that nitinol rods were comparable to titanium rods in compression, but had higher torsional yield point and torsional toughness. While nitinol trended toward superior fatigue resistance, there was no significant difference in fatigue resistance between nitinol and titanium constructs.
GLOBAL SPINE JOURNAL
(2021)
Article
Neurosciences
Akihiko Asao, Kento Wada, Tomonori Nomura, Kenichi Shibuya
Summary: The combination of repetitive peripheral magnetic stimulation (rPMS) with motor imagery (MI) enhances corticospinal excitability, with over 10 minutes of intermittent rPMS combined with MI showing a greater effect than rPMS alone on corticospinal excitability.
NEUROSCIENCE LETTERS
(2022)
Article
Medicine, Research & Experimental
Ryo Hirabayashi, Mutsuaki Edama, Mai Takeda, Yuki Yamada, Hirotake Yokota, Chie Sekine, Hideaki Onishi
Summary: This study aimed to evaluate the effects of the participant's attention target during repetitive passive movement (RPM) intervention on joint movement function and reciprocal inhibition. The results showed that the attention target had a significant impact on the intervention effect, which has implications for improving the effectiveness of rehabilitation.
EUROPEAN JOURNAL OF MEDICAL RESEARCH
(2023)
Article
Multidisciplinary Sciences
Justine Magnuson, Mehmet A. A. Ozdemir, Elon Mathieson, Sofia Kirkman, Brice Passera, Sumientra Rampersad, Alyssa B. B. Dufour, Dana Brooks, Alvaro Pascual-Leone, Peter J. J. Fried, Mouhsin M. M. Shafi, Recep A. A. Ozdemir
Summary: This study comprehensively evaluated the neuromodulatory effects of various rTMS protocols on corticospinal excitability. The results showed that these protocols did not significantly modulate corticospinal excitability and had poor reproducibility. These findings question the effectiveness and reliability of widely used rTMS techniques in modulating corticospinal excitability.
Review
Medicine, General & Internal
Haihua Xie, Dan Xiong, Pan Zhu, Hao Li, Hong Zhang, Jie Tan, Ning Zhao
Summary: This study aims to evaluate the clinical effect and safety of repetitive transcranial magnetic stimulation (rTMS) on poststroke memory disorder (PSMD) through analyzing randomized controlled trials. Various outcome measures will be included and statistical analysis will be conducted to provide reliable conclusions regarding the efficacy of rTMS in treating PSMD.
Article
Neurosciences
Hayk A. Petrosyan, Valentina Alessi, Arsen S. Hunanyan, Sue A. Sisto, Victor L. Arvanian
JOURNAL OF NEUROPHYSIOLOGY
(2015)
Article
Clinical Neurology
Saman Shabani, Susan M. Fiore, Roberta Seidman, Raphael P. Davis
JOURNAL OF NEUROSURGERY-SPINE
(2015)
Article
Medicine, General & Internal
P. J. Hutchinson, A. G. Kolias, I. S. Timofeev, E. A. Corteen, M. Czosnyka, J. Timothy, I. Anderson, D. O. Bulters, A. Belli, C. A. Eynon, J. Wadley, A. D. Mendelow, P. M. Mitchell, M. H. Wilson, G. Critchley, J. Sahuquillo, A. Unterberg, F. Servadei, G. M. Teasdale, J. D. Pickard, D. K. Menon, G. D. Murray, P. J. Kirkpatrick
NEW ENGLAND JOURNAL OF MEDICINE
(2016)
Article
Clinical Neurology
Richard Bram, Susan Fiore, Daryl McHugh, Ghassan J. Samara, Raphael P. Davis
JOURNAL OF CLINICAL NEUROSCIENCE
(2017)
Article
Neurosciences
Hayk A. Petrosyan, Valentina Alessi, Sue A. Sisto, Mark Kaufman, Victor L. Arvanian
NEUROSCIENCE LETTERS
(2017)
Article
Clinical Neurology
J. Raymond, R. Klink, M. Chagnon, S. L. Barnwell, A. J. Evans, J. Mocco, B. L. Hoh, A. S. Turk, R. D. Turner, H. Desal, D. Fiorella, S. Bracard, A. Weill, F. Guilbert, D. Roy
AMERICAN JOURNAL OF NEURORADIOLOGY
(2014)
Article
Biochemistry & Molecular Biology
H. A. Petrosyan, V. Alessi, V. Singh, A. S. Hunanyan, J. M. Levine, V. L. Arvanian
Article
Medicine, General & Internal
Colin P. Derdeyn, Marc I. Chimowitz, Michael J. Lynn, David Fiorella, Tanya N. Turan, L. Scott Janis, Jean Montgomery, Azhar Nizam, Bethany F. Lane, Helmi L. Lutsep, Stanley L. Barnwell, Michael F. Waters, Brian L. Hoh, J. Maurice Hourihane, Elad I. Levy, Andrei V. Alexandrov, Mark R. Harrigan, David Chiu, Richard P. Klucznik, Joni M. Clark, Cameron G. McDougall, Mark D. Johnson, G. Lee Pride, John R. Lynch, Osama O. Zaidat, Zoran Rumboldt, Harry J. Cloft
Article
Clinical Neurology
Daryl C. McHugh, Susan M. Fiore, Nancy Strong, Michael R. Egnor
PEDIATRIC NEUROSURGERY
(2019)
Article
Neurosciences
Hayk Petrosyan, Li Liang, Asrat Tesfa, Sue A. Sisto, Magda Fahmy, Victor L. Arvanian
EUROPEAN JOURNAL OF NEUROSCIENCE
(2020)
Article
Critical Care Medicine
Elliott Bennett-Guerrero, Jamie L. Romeiser, Lillian R. Talbot, Tahmeena Ahmed, Linda J. Mamone, Sunitha M. Singh, Janet C. Hearing, Huda Salman, Dishaw D. Holiprosad, Alex T. Freedenberg, Jason A. Carter, Nicholas J. Browne, Megan E. Cosgrove, Margaret E. Shevik, Laura M. Generale, Margaret A. Andrew, Sharon Nachman, Bettina C. Fries
Summary: This study found that administration of convalescent plasma to hospitalized patients with coronavirus disease 2019 infection did not improve outcomes, despite convalescent plasma having high neutralizing activity and increasing antibodies to severe acute respiratory syndrome coronavirus 2.
CRITICAL CARE MEDICINE
(2021)
Article
Surgery
Zhe Wang, Nathan J. Winans, Zirun Zhao, Megan E. Cosgrove, Theresa Gammel, Jordan R. Saadon, Racheed Mani, Bharadwaj Ravi, Susan M. Fiore, Charles B. Mikell, Sima Mofakham
Summary: This study investigated the association between posttraumatic agitation and recovery of consciousness in severe traumatic brain injury (sTBI) patients. Results showed a positive correlation between the development of agitation and the ability to follow commands, indicating the potential for neurological recovery in patients exhibiting posttraumatic agitation. Further research is needed to identify neural correlates of posttraumatic agitation and consciousness recovery after sTBI.
FRONTIERS IN SURGERY
(2021)
Article
Neurosciences
Victor L. Arvanian, Li Liang, Asrat Tesfa, Magda Fahmy, Hayk A. Petrosyan
Summary: The recent study suggests that low-frequency spinal electromagnetic stimulation can improve transmission in damaged spinal cord and reduce chronic low back pain. This non-invasive treatment approach shows potential for alleviating chronic low back pain.
NEUROSCIENCE LETTERS
(2022)
Article
Clinical Neurology
Jaakko Vallinoja, Timo Nurmi, Julia Jaatela, Vincent Wens, Mathieu Bourguignon, Helena Maenpaa, Harri Piitulainen
Summary: The study aimed to assess the effects of lesions related to spastic diplegic cerebral palsy on functional connectivity. Using multiple imaging modalities, the researchers found enhanced functional connectivity in the sensorimotor network of individuals with spastic diplegic cerebral palsy, which was not correlated with hand coordination performance.
CLINICAL NEUROPHYSIOLOGY
(2024)
Article
Clinical Neurology
Francesca Ginatempo, Nicola Loi, John C. Rothwell, Franca Deriu
Summary: This study comprehensively investigated sensorimotor integration in the cranial-cervical muscles of healthy adults and found that the integration of sensory inputs with motor output is profoundly influenced by the type of sensory afferent involved and the functional role played by the target muscle.
CLINICAL NEUROPHYSIOLOGY
(2024)