Article
Pediatrics
Michelle Baczynski, Ashraf Kharrat, Faith Zhu, Xiang Y. Ye, Prakesh S. Shah, Dany E. Weisz, Amish Jain
Summary: This study found that within +/- 4 hours of bloodstream infection onset, low mean blood pressure and high base deficit were independently associated with mortality in preterm neonates. The AUC for base deficit was 0.87, increasing to 0.91 with the addition of mean blood pressure.
JOURNAL OF PEDIATRICS
(2021)
Article
Environmental Sciences
Ram C. Siwakoti, Amber Cathey, Kelly K. Ferguson, Wei Hao, David E. Cantonwine, Bhramar Mukherjee, Thomas F. McElrath, John D. Meeker
Summary: This study found that prenatal exposure to PFAS may have an impact on pregnancy outcomes, including preterm birth and large-for-gestational age (LGA). However, the effects of PFAS on these outcomes depend on the fetal sex. Specifically, certain PFAS were associated with placental preterm birth, with stronger associations observed in male fetuses. For LGA, different PFAS had different effects in females and males.
ENVIRONMENTAL RESEARCH
(2023)
Article
Endocrinology & Metabolism
Ke Huang, Shuting Si, Ruimin Chen, Chunlin Wang, Shaoke Chen, Yan Liang, Hui Yao, Rongxiu Zheng, Fang Liu, Binyan Cao, Zhe Su, Maimaiti Mireguli, Feihong Luo, Pin Li, Hongwei Du, Min Zhu, Yu Yang, Lanwei Cui, Yunxian Yu, Junfen Fu
Summary: The study in China found that preterm birth increased the risk of childhood T1DM, while high birth weight only affected girls. Early prevention of T1DM may start with prenatal care, and more attention should be paid to children with preterm birth and girls with high birth weight after birth.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Medicine, General & Internal
Yulika Yoshida-Montezuma, Branavan Sivapathasundaram, Hilary K. Brown, Charles Keown-Stoneman, Russell J. de Souza, Teresa To, Cornelia M. Borkhoff, Catherine S. Birken, Jonathon L. Maguire, Laura N. Anderson
Summary: Children born late preterm and moderately preterm have higher cardiometabolic risk, suggesting that screening and early-life interventions for these children may prevent cardiometabolic outcomes.
Article
Allergy
Jhill Shah, Iskander L. C. Shadid, Vincent J. Carey, Nancy Laranjo, George T. O'Connor, Robert S. Zeiger, Leonard Bacharier, Augusto A. Litonjua, Scott T. Weiss, Hooman Mirzakhani
Summary: This study investigates the association between longitudinal weight for age (WFA) and the odds of asthma/recurrent wheeze in preterm and term offspring. It is found that increasing standardized WFA is associated with higher odds of asthma/recurrent wheeze in term children, while in preterm children, a higher standardized WFA during catch-up growth may decrease the odds of asthma/recurrent wheeze associated with pre-maturity.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE
(2023)
Article
Endocrinology & Metabolism
Junlan Yang, Ze Wang, Hairu Cao, Lu Liu, Qiaona Yuan, Haiyan Xu, Rong Tang
Summary: This study suggests that delayed blastocyst transfer on day 6 compared with day 5 may adversely affect the pregnancy rate, but it does not affect neonatal birth weight.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Endocrinology & Metabolism
Yiting Mao, Chen Zhang, Yinyu Wang, Yicong Meng, Lei Chen, Cindy-Lee Dennis, Jianzhong Sheng, Yanting Wu, Hefeng Huang
Summary: The study identified a relationship between paternal age and infant birth weight, with advanced paternal age increasing the risk of SGA among preterm infants and LGA among term infants. These findings suggest potential implications for preconception care and the need for antenatal monitoring.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Pediatrics
Hayato Go, Koichi Hashimoto, Hajime Maeda, Kei Ogasawara, Yohei Kume, Tsuyoshi Murata, Akiko Sato, Yuka Ogata, Kosei Shinoki, Hidekazu Nishigori, Atsuko Ikeda-Araki, Keiya Fujimori, Seiji Yasumura, Mitsuaki Hosoya, Michihiro Kamijima
Summary: This study investigated the associations between cord blood total cholesterol (TC) and triglyceride (TG) levels and perinatal factors in Japanese neonates. The study found that gestational age and birth weight were significantly associated with cord blood TC and TG levels. Mean cord blood TC and TG levels decreased during the preterm period but increased during the term. Additionally, the mean cord blood TC and TG levels decreased across all birth weight categories. Maternal complications such as parity, hypertensive disorders of pregnancy, premature rupture of membranes, maternal obesity, and income level were also associated with cord TC and TG levels.
EUROPEAN JOURNAL OF PEDIATRICS
(2023)
Article
Cardiac & Cardiovascular Systems
Casey Crump, Jan Sundquist, Kristina Sundquist
Summary: This study found that preterm delivery is associated with an increased risk of stroke, which remains elevated for at least 40 years after delivery and is independent of other factors and familial influences.
Article
Pediatrics
Alejandra Rodriguez-Fernandez, Marcela Ruiz-De la Fuente, Ximena Sanhueza-Riquelme, Julio Parra-Flores, Maria Dolores Marrodan, Eduard Maury-Sintjago
Summary: The study found that maternal factors, such as educational attainment and age, are associated with preterm and low-birthweight births in Chile. Mothers with less than 12 years of education and mothers aged 35 or older were found to be at a higher risk for preterm and low-birthweight newborns.
Article
Medicine, General & Internal
Andrew W. Manigault, Stephen J. Sheinkopf, Brian S. Carter, Jennifer Check, Jennifer Helderman, Julie A. Hofheimer, Elisabeth C. McGowan, Charles R. Neal, Michael O'Shea, Steven Pastyrnak, Lynne M. Smith, Todd M. Everson, Carmen J. Marsit, Lynne M. Dansereau, Sheri A. DellaGrotta, Barry M. Lester
Summary: This study examined the association between acoustic cry characteristics at neonatal intensive care unit discharge and behavioral and developmental outcomes at age 2 years in very preterm infants. The findings suggest that acoustic cry characteristics are associated with developmental and behavioral outcomes at age 2 years. Therefore, acoustic cry characteristics may be used for early identification of risk for long-term developmental and behavioral deficits in children.
Article
Environmental Sciences
Yiwen Zhang, Tingting Ye, Pei Yu, Rongbin Xu, Gongbo Chen, Wenhua Yu, Jiangning Song, Yuming Guo, Shanshan Li
Summary: Exposure to wildfire-specific PM2.5 is associated with increased risk of preterm birth and term low birth weight. Pregnant women exposed to wildfire-specific PM2.5 are at higher risk for preterm birth and term low birth weight. This study emphasizes the importance of increased attention to pregnant women by policy makers.
ENVIRONMENT INTERNATIONAL
(2023)
Article
Medicine, General & Internal
Yoo Hyun Chung, In Sun Hwang, Gyul Jung, Hyun Sun Ko
Summary: This study aimed to investigate the association between parental age and the risks of term low birth weight and macrosomia. The results suggest that both maternal and paternal age are significantly associated with these risks. Additionally, parental education levels are also correlated with term low birth weight and macrosomia.
Article
Immunology
Anne L. Dunlop, Glen A. Satten, Yi-Juan Hu, Anna K. Knight, Cherie C. Hill, Michelle L. Wright, Alicia K. Smith, Timothy D. Read, Bradley D. Pearce, Elizabeth J. Corwin
Summary: An early pregnancy vaginal community state type III or IV was associated with an increased risk of spontaneous preterm birth (sPTB) but not early term birth (sETB) in African American women. Specific taxa within the early pregnancy vaginal microbiome were associated with either sPTB or sETB.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2021)
Article
Dermatology
Trine Gerner, Maria Rasmussen Rinnov, Anne-Sofie Halling, Nina Haarup Ravn, Mette Hjorslev Knudgaard, Caroline Ewertsen, Simon Trautner, Ivone Jakasa, Sanja Kezic, Lone Skov, Jacob P. Thyssen
Summary: This prospective birth cohort study found that term newborns are more susceptible to infantile atopic dermatitis compared to preterm newborns, with an earlier age of onset and more severe symptoms. The environmental risk factors for atopic dermatitis were generally similar between preterm and term newborns, except for winter and autumn births. Filaggrin gene mutations were less prevalent in preterm newborns than term newborns.
ACTA DERMATO-VENEREOLOGICA
(2022)
Article
Nutrition & Dietetics
Lilia Bliznashka, Dana C. McCoy, Saima Siyal, Christopher R. Sudfeld, Wafaie W. Fawzi, Aisha K. Yousafzai
Summary: The study found that a responsive stimulation and nutrition intervention improved children's cognitive, language, and motor development through child diet and mother-child interactions. While it did not impact child growth or socio-emotional development directly, positive indirect effects were observed on child growth through child diet and on socio-emotional development through both child diet and mother-child interactions. Child diet was identified as a common mechanism to improve growth and development, whereas mother-child interactions emerged as a distinct mechanism to enhance child development. The results suggest that interventions utilizing both mechanisms are more likely to be effective in improving child outcomes compared to interventions focusing on only one of these mechanisms.
MATERNAL AND CHILD NUTRITION
(2022)
Article
Communication
Hermano Alexandre Lima Rocha, Luciano Lima Correia, Alvaro Jorge Madeiro Leite, Marcia Maria Tavares Machado, Ana Cristina Lindsay, Sabrina Gabriele Maia Oliveira Rocha, Jocileide Sales Campos, Anamaria Cavalcante e Silva, Christopher Robert Sudfeld
Summary: The study shows a significant increase in screen time among 3-6-year-old children in Ceara, Brazil during the COVID-19 pandemic, with children participating in remote learning activities having lower television time. Interventions to reduce excess screen time should be developed and evaluated.
JOURNAL OF CHILDREN AND MEDIA
(2022)
Article
Nutrition & Dietetics
Alfa Muhihi, Wafaie W. Fawzi, Said Aboud, Tumaini J. Nagu, Nzovu Ulenga, Molin Wang, Ferdinand Mugusi, Christopher R. Sudfeld
Summary: A study conducted on adults initiating ART in Tanzania showed that vitamin D supplementation did not have an effect on HIV progression, viral suppression, comorbidities, weight-related indicators, or depression.
JOURNAL OF NUTRITION
(2022)
Article
Infectious Diseases
Ajibola Ibraheem Abioye, Christopher R. Sudfeld, Michael D. Hughes, Said Aboud, Alfa Muhihi, Nzovu Ulenga, Tumaini J. Nagu, Molin Wang, Ferdinand Mugusi, Wafaie W. Fawzi
Summary: This study evaluated the trajectory of iron status among people living with HIV during the first year of highly active antiretroviral therapy (HAART) and analyzed the influence of inflammation correction methods on iron status research. The findings showed that elevated iron status was associated with HIV-1 viral load and underweight.
Article
Nutrition & Dietetics
Zhonghai Zhu, Yingze Zhu, Liang Wang, Qi Qi, Lin Huang, Amanuel Kidane Andegiorgish, Mohamed Elhoumed, Yue Cheng, Michael J. Dibley, Christopher R. Sudfeld, Lingxia Zeng
Summary: Antenatal micronutrient supplementation has been shown to improve birth outcomes and child development. However, its effect on offspring socioemotional outcomes remains unknown. This study found that iron supplementation during pregnancy reduced adolescent emotional and behavioral problem scores, providing support for expanding coverage of iron-containing prenatal supplements in resource-limited settings.
CLINICAL NUTRITION
(2023)
Article
Nutrition & Dietetics
Ajibola Ibraheem Abioye, Michael D. Hughes, Christopher R. Sudfeld, Zulfiqarali Premji, Said Aboud, Davidson H. Hamer, Drucilla J. Roberts, Christopher P. Duggan, Wafaie W. Fawzi
Summary: The impact of iron deficiency anemia (IDA) and non-iron deficiency anemia (NIDA) on pregnancy and newborn outcomes, as well as the effectiveness of iron supplementation, remains uncertain. This study found that iron supplementation is effective even among pregnant women with NIDA.
EUROPEAN JOURNAL OF NUTRITION
(2023)
Article
Immunology
Ajibola Ibraheem Abioye, Michael D. D. Hughes, Christopher R. R. Sudfeld, Ramadhani Abdallah Noor, Sheila Isanaka, Zohra Lukmanji, Ferdinand Mugusi, Wafaie W. W. Fawzi
Summary: This study evaluated the relationship between dietary iron intake levels and sources with mortality and clinical outcomes among adults initiating HAART. The results showed that intake of red meat and legumes was associated with a lower risk of mortality and critical HIV-related outcomes.
JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES
(2023)
Article
Medicine, General & Internal
Linda Vesel, Roopa M. Bellad, Karim Manji, Friday Saidi, Esther Velasquez, Christopher R. Sudfeld, Katharine Miller, Mohamed Bakari, Kristina Lugangira, Rodrick Kisenge, Nahya Salim, Sarah Somji, Irving Hoffman, Kingsly Msimuko, Tisungane Mvalo, Fadire Nyirenda, Melda Phiri, Leena Das, Sangappa Dhaded, Shivaprasad S. Goudar, Veena Herekar, Yogesh Kumar, M. B. Koujalagi, Gowdar Guruprasad, Sanghamitra Panda, Latha G. Shamanur, Manjunath Somannavar, Sunil S. Vernekar, Sujata Misra, Linda Adair, Griffith Bell, Bethany A. Caruso, Christopher Duggan, Katelyn Fleming, Kiersten Israel-Ballard, Eliza Fishman, Anne C. C. Lee, Stuart Lipsitz, Kimberly L. Mansen, Stephanie L. Martin, Rana R. Mokhtar, Krysten North, Arthur Pote, Lauren Spigel, Danielle E. Tuller, Melissa Young, Katherine E. A. Semrau
Summary: This study aimed to describe the feeding profile of low birthweight infants in the first half of infancy and examine early risk factors and growth patterns of poor 6-month growth outcomes. The study found that preterm and small-for-gestational age infants had a higher risk of poor growth at 6 months, and infants who did not regain birthweight by 2 weeks also had a higher risk. Therefore, early interventions including optimal feeding support, action-oriented growth monitoring, and understanding the needs and growth patterns of small-for-gestational age infants are needed to promote appropriate weight gain and proactive management of vulnerable infants.
Article
Pediatrics
Hermano A. L. Rocha, Marcia M. T. Machado, Onelia M. M. L. de Santana, Sabrina G. M. O. Rocha, Camila M. de Aquino, Laecia G. A. Gomes, Lucas de S. Albuquerque, Maria D. de A. Soares, Alvaro J. M. Leite, Luciano L. Correia, Christopher R. Sudfeld
Summary: This study examines the association between sociodemographic and maternal education factors and child development in families living below the poverty line in Northeastern Brazil. The findings suggest that maternal educational attainment is associated with a higher risk of developmental delay in children, except for the fine motor domain. The risk of delay in at least one domain is 2.5 times higher in mothers with lower levels of education.
Article
Public, Environmental & Occupational Health
Arvin Saleh, Nandita Perumal, Alfa Muhihi, Christopher P. Duggan, Nzovu Ulenga, Fadhlun M. Alwy Al-Beity, Said Aboud, Wafaie W. Fawzi, Karim P. Manji, Christopher R. Sudfeld
Summary: Children born to mothers living with HIV may be at a greater risk of poor growth and development outcomes compared to their HIV-unexposed peers. A study conducted in Tanzania found that symptoms of maternal antenatal depression were associated with infant wasting, while greater social support was associated with better cognitive and motor development scores in infants.
Article
Health Care Sciences & Services
Mathilda Regan, Chao Cheng, Eric Mboggo, Elysia Larson, Irene Andrew Lema, Lucy Magesa, Lameck Machumi, Nzovu Ulenga, David Sando, Mary Mwanyika-Sando, Dale A. Barnhart, Biling Hong, Ester Mungure, Nan Li, Hellen Siril, Phares Mujinja, Helga Naburi, Charles Kilewo, Anna Mia Ekstrom, Pascal Geldsetzer, Wafaie Fawzi, Till Barnighausen, Christopher R. Sudfeld, Donna Spiegelman
Summary: This study in Tanzania found that training community health workers (CHWs) in the public sector can significantly increase the likelihood of pregnant women attending antenatal care (ANC) visits and have a positive impact on the total number of ANC visits. However, additional interventions are needed to promote early initiation of ANC.
HEALTH POLICY AND PLANNING
(2023)
Article
Public, Environmental & Occupational Health
Jinyi Zhu, Goodluck Lyatuu, Christopher R. Sudfeld, Anna Kiravu, David Sando, Lameck Machumi, John Minde, Fikiri Chisonjela, Ted Cohen, Nicolas A. Menzies
Summary: Isoniazid preventive therapy (IPT) can prevent tuberculosis among people receiving antiretroviral therapy (ART). This study found that providing ART earlier through IPT can significantly improve health impact and cost-effectiveness.
LANCET GLOBAL HEALTH
(2022)
Article
Public, Environmental & Occupational Health
Jinyi Zhu, Goodluck Lyatuu, Christopher R. Sudfeld, Anna Kiravu, David Sando, Lameck Machumi, John Minde, Fikiri Chisonjela, Ted Cohen, Nicolas A. Menzies
Summary: The study found that providing IPT to recent ART cohorts remains highly cost-effective, and the health impact and cost-effectiveness of IPT are estimated to improve as patients initiate ART earlier in the course of infection.
LANCET GLOBAL HEALTH
(2022)
Article
Public, Environmental & Occupational Health
Ellen C. Caniglia, Rebecca Zash, Sonja A. Swanson, Emily Smith, Christopher Sudfeld, Julia L. Finkelstein, Modiegi Diseko, Gloria Mayondi, Mompati Mmalane, Joseph Makhema, Wafaie Fawzi, Shahin Lockman, Roger L. Shapiro
Summary: This study investigated the impact of various antenatal nutrient supplementation strategies on birth outcomes, finding that combined iron and folic acid supplementation as well as multiple micronutrient supplementation (MMS) were associated with improved birth outcomes compared to folic acid or iron supplementation alone. This was especially pronounced in women with HIV and those aged 35 years and older.
LANCET GLOBAL HEALTH
(2022)
