Synthesis of 3D Silver-Graphene-Titanium Dioxide Composite via Aerosol Spray Pyrolysis for Sensitive Glucose Biosensor

A sensitive glucose biosensor was developed based on the adsorption of glucose oxidase by a three-dimensional silver-graphene-titanium dioxide (3D Ag-GR-TiO2) composite electrode. Aerosol spray pyrolysis was employed to synthesize the 3D Ag-GR-TiO2 composite using a colloidal mixture of a silver acetate precursor (C2H3AgO2), graphene oxide, and TiO2 nanoparticles. The effects of the operating temperature, gas flowrate, and TiO2 concentration on the particle properties were investigated. The particle morphology of all 3D Ag-GR-TiO2 composites was spherical in shape. The average sizes of composites could be controlled from 0.45 to 0.64 mu m with the variation of process variables. Ag nanoparticles less than 10nm in diameter were deposited on the surfaces of the TiO2 nanoparticles and GR after a reduction process. The characteristics of the glucose biosensor fabricated with the as-prepared 3D Ag-GR-TiO2 composite were assessed through cyclic voltammetry measurements. The biosensor exhibited a high current flow as well as clear redox peaks, resulting in a superior ability of the catalyst in terms of the electrochemical reactions. The highest sensitivity of glucose biosensor was obtained by 3D Ag-GR-TiO2 composite, which was 12.2 mu A/mM center dot cm(2), among 3D Ag-GR-TiO2, 3D Ag-GR, and 3D GR-TiO2 composites. Copyright 2015 American Association for Aerosol Research