Cyclophilin A stabilizes the HIV-1 capsid through a novel non-canonical binding site

Dynamic allostery governs cyclophilin A–HIV capsid interplay

(2015) Manman Lu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crystal structure of TRIM20 C-terminal coiled-coil/B30.2 fragment: implications for the recognition of higher order oligomers

(2015) Christopher Weinert et al.   Scientific Reports

GPU-accelerated analysis and visualization of large structures solved by molecular dynamics flexible fitting

(2014) John E. Stone et al.   FARADAY DISCUSSIONS

Structural studies of postentry restriction factors reveal antiparallel dimers that enable avid binding to the HIV-1 capsid lattice

(2014) David C. Goldstone et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The tripartite motif coiled-coil is an elongated antiparallel hairpin dimer

(2014) J. G. Sanchez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cyclophilin A promotes HIV-1 reverse transcription but its effect on transduction correlates best with its effect on nuclear entry of viral cDNA

(2014) Alberto De Iaco et al.   Retrovirology

A model for cofactor use during HIV-1 reverse transcription and nuclear entry

(2014) Laura Hilditch et al.   Current Opinion in Virology

The Capsids of HIV-1 and HIV-2 Determine Immune Detection of the Viral cDNA by the Innate Sensor cGAS in Dendritic Cells

(2013) Xavier Lahaye et al.   IMMUNITY

Polarizable Force Field for Peptides and Proteins Based on the Classical Drude Oscillator

(2013) Pedro E. M. Lopes et al.   Journal of Chemical Theory and Computation

Magic Angle Spinning NMR Reveals Sequence-Dependent Structural Plasticity, Dynamics, and the Spacer Peptide 1 Conformation in HIV-1 Capsid Protein Assemblies

(2013) Yun Han et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Retrovirus Restriction by TRIM5 Proteins Requires Recognition of Only a Small Fraction of Viral Capsid Subunits

(2013) J. Shi et al.   JOURNAL OF VIROLOGY

HIV-1 evades innate immune recognition through specific cofactor recruitment

(2013) Jane Rasaiyaah et al.   NATURE

Mature HIV-1 capsid structure by cryo-electron microscopy and all-atom molecular dynamics

(2013) Gongpu Zhao et al.   NATURE

Virion stiffness regulates immature HIV-1 entry

(2013) Hong-Bo Pang et al.   Retrovirology

Extreme Genetic Fragility of the HIV-1 Capsid

(2013) Suzannah J. Rihn et al.   PLoS Pathogens

Optimization of the Additive CHARMM All-Atom Protein Force Field Targeting Improved Sampling of the Backbone ϕ, ψ and Side-Chain χ1 and χ2 Dihedral Angles

(2012) Robert B. Best et al.   Journal of Chemical Theory and Computation

RELION: Implementation of a Bayesian approach to cryo-EM structure determination

(2012) Sjors H.W. Scheres   JOURNAL OF STRUCTURAL BIOLOGY

The Host Proteins Transportin SR2/TNPO3 and Cyclophilin A Exert Opposing Effects on HIV-1 Uncoating

(2012) V. B. Shah et al.   JOURNAL OF VIROLOGY

Structural insight into HIV-1 capsid recognition by rhesus TRIM5 

(2012) H. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Requirement for Nucleoporin NUP153 during Human Immunodeficiency Virus Type 1 Infection Is Determined by the Viral Capsid

(2011) K. A. Matreyek et al.   JOURNAL OF VIROLOGY

HIV-1 Capsid-Cyclophilin Interactions Determine Nuclear Import Pathway, Integration Targeting and Replication Efficiency

(2011) Torsten Schaller et al.   PLoS Pathogens

Rhesus TRIM5α Disrupts the HIV-1 Capsid at the Inter­Hexamer Interfaces

(2011) Gongpu Zhao et al.   PLoS Pathogens

Flexible Use of Nuclear Import Pathways by HIV-1

(2010) KyeongEun Lee et al.   Cell Host & Microbe

High-Performance Scalable Molecular Dynamics Simulations of a Polarizable Force Field Based on Classical Drude Oscillators in NAMD

(2010) Wei Jiang et al.   Journal of Physical Chemistry Letters

Solid-State NMR Studies of HIV-1 Capsid Protein Assemblies

(2010) Yun Han et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Strain-Specific Differences in the Impact of Human TRIM5 , Different TRIM5  Alleles, and the Inhibition of Capsid-Cyclophilin A Interactions on the Infectivity of HIV-1

(2010) E. Battivelli et al.   JOURNAL OF VIROLOGY

Small-Molecule Inhibition of Human Immunodeficiency Virus Type 1 Infection by Virus Capsid Destabilization

(2010) J. Shi et al.   JOURNAL OF VIROLOGY

A cryptic sensor for HIV-1 activates antiviral innate immunity in dendritic cells

(2010) Nicolas Manel et al.   NATURE

Structural Convergence between Cryo-EM and NMR Reveals Intersubunit Interactions Critical for HIV-1 Capsid Function

(2009) In-Ja L. Byeon et al.   CELL

Target Cell Type-Dependent Modulation of Human Immunodeficiency Virus Type 1 Capsid Disassembly by Cyclophilin A

(2009) Y. Li et al.   JOURNAL OF VIROLOGY

Molecular dynamics flexible fitting: A practical guide to combine cryo-electron microscopy and X-ray crystallography

(2009) Leonardo G. Trabuco et al.   METHODS

CHARMM-GUI: A web-based graphical user interface for CHARMM

(2008) Sunhwan Jo et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Cyclophilin A Levels Dictate Infection Efficiency of Human Immunodeficiency Virus Type 1 Capsid Escape Mutants A92E and G94D

(2008) L. M. J. Ylinen et al.   JOURNAL OF VIROLOGY

Cyclophilin A-Dependent Restriction of Human Immunodeficiency Virus Type 1 Capsid Mutants for Infection of Nondividing Cells

(2008) M. Qi et al.   JOURNAL OF VIROLOGY

Determinants of cyclophilin A-dependent TRIM5α restriction against HIV-1

(2008) Tsai-Yu Lin et al.   VIROLOGY