Integrative functional genomics identifies regulatory mechanisms at coronary artery disease loci
出版年份 2016 全文链接
标题
Integrative functional genomics identifies regulatory mechanisms at coronary artery disease loci
作者
关键词
-
出版物
Nature Communications
Volume 7, Issue -, Pages 12092
出版商
Springer Nature
发表日期
2016-07-08
DOI
10.1038/ncomms12092
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Prediction of Causal Candidate Genes in Coronary Artery Disease LociSignificance
- (2015) Ingrid Brænne et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Systems Genetics Analysis of Genome-Wide Association Study Reveals Novel Associations Between Key Biological Processes and Coronary Artery DiseaseSignificance
- (2015) Sujoy Ghosh et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Defining cell types and states with single-cell genomics
- (2015) Cole Trapnell GENOME RESEARCH
- Genome-Wide Significant Loci: How Important Are They?
- (2015) Johan L.M. Björkegren et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Integrative analysis of 111 reference human epigenomes
- (2015) Anshul Kundaje et al. NATURE
- Analysis of intronic and exonic reads in RNA-seq data characterizes transcriptional and post-transcriptional regulation
- (2015) Dimos Gaidatzis et al. NATURE BIOTECHNOLOGY
- A comprehensive 1000 Genomes–based genome-wide association meta-analysis of coronary artery disease
- (2015) Majid Nikpay et al. NATURE GENETICS
- IL-6 as a keystone cytokine in health and disease
- (2015) Christopher A Hunter et al. NATURE IMMUNOLOGY
- KLF4-dependent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque pathogenesis
- (2015) Laura S Shankman et al. NATURE MEDICINE
- Sensitive detection of chromatin-altering polymorphisms reveals autoimmune disease mechanisms
- (2015) Ricardo Cruz-Herrera del Rosario et al. NATURE METHODS
- Bayesian integration of genetics and epigenetics detects causal regulatory SNPs underlying expression variability
- (2015) Avinash Das et al. Nature Communications
- PDGFRβ signalling regulates local inflammation and synergizes with hypercholesterolaemia to promote atherosclerosis
- (2015) Chaoyong He et al. Nature Communications
- Coronary Artery Disease Associated Transcription Factor TCF21 Regulates Smooth Muscle Precursor Cells That Contribute to the Fibrous Cap
- (2015) Sylvia T. Nurnberg et al. PLoS Genetics
- Disproportionate Contributions of Select Genomic Compartments and Cell Types to Genetic Risk for Coronary Artery Disease
- (2015) Hong-Hee Won et al. PLoS Genetics
- Characterization of TCF21 Downstream Target Regions Identifies a Transcriptional Network Linking Multiple Independent Coronary Artery Disease Loci
- (2015) Olga Sazonova et al. PLoS Genetics
- The Genetic and Mechanistic Basis for Variation in Gene Regulation
- (2015) Athma A. Pai et al. PLoS Genetics
- Transdifferentiation of Vascular Smooth Muscle Cells to Macrophage-Like Cells During Atherogenesis
- (2014) Susanne Feil et al. CIRCULATION RESEARCH
- Cyclin-dependent kinase inhibitor 2B regulates efferocytosis and atherosclerosis
- (2014) Yoko Kojima et al. JOURNAL OF CLINICAL INVESTIGATION
- Obesity-associated variants within FTO form long-range functional connections with IRX3
- (2014) Scott Smemo et al. NATURE
- Genetic and epigenetic fine mapping of causal autoimmune disease variants
- (2014) Kyle Kai-How Farh et al. NATURE
- Innate Immune Activity Conditions the Effect of Regulatory Variants upon Monocyte Gene Expression
- (2014) B. P. Fairfax et al. SCIENCE
- Approaches for establishing the function of regulatory genetic variants involved in disease
- (2014) Julian Charles Knight Genome Medicine
- Coronary Heart Disease-Associated Variation in TCF21 Disrupts a miR-224 Binding Site and miRNA-Mediated Regulation
- (2014) Clint L. Miller et al. PLoS Genetics
- Integrative Genomics Reveals Novel Molecular Pathways and Gene Networks for Coronary Artery Disease
- (2014) Ville-Petteri Mäkinen et al. PLoS Genetics
- Risk loci for coronary artery calcification replicated at 9p21 and 6q24 in the Heinz Nixdorf Recall Study
- (2013) Sonali Pechlivanis et al. BMC Medical Genetics
- Combinatorial effects of multiple enhancer variants in linkage disequilibrium dictate levels of gene expression to confer susceptibility to common traits
- (2013) O. Corradin et al. GENOME RESEARCH
- The Transcription Factor TEAD1 Represses Smooth Muscle-specific Gene Expression by Abolishing Myocardin Function
- (2013) Fang Liu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Genotype-Tissue Expression (GTEx) project
- (2013) John Lonsdale et al. NATURE GENETICS
- Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position
- (2013) Jason D Buenrostro et al. NATURE METHODS
- Chromatin modifiers and remodellers: regulators of cellular differentiation
- (2013) Taiping Chen et al. NATURE REVIEWS GENETICS
- Chromatin stretch enhancer states drive cell-specific gene regulation and harbor human disease risk variants
- (2013) S. C. J. Parker et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- An Erythroid Enhancer of BCL11A Subject to Genetic Variation Determines Fetal Hemoglobin Level
- (2013) D. E. Bauer et al. SCIENCE
- The ZC3HC1 rs11556924 polymorphism is associated with increased carotid intima-media thickness in patients with rheumatoid arthritis
- (2013) Raquel López-Mejías et al. ARTHRITIS RESEARCH & THERAPY
- Disease-Related Growth Factor and Embryonic Signaling Pathways Modulate an Enhancer of TCF21 Expression at the 6q23.2 Coronary Heart Disease Locus
- (2013) Clint L. Miller et al. PLoS Genetics
- Vascular smooth muscle cell phenotypic plasticity: focus on chromatin remodelling
- (2012) J. M. Spin et al. CARDIOVASCULAR RESEARCH
- Pod1/Tcf21 is regulated by retinoic acid signaling and inhibits differentiation of epicardium-derived cells into smooth muscle in the developing heart
- (2012) Caitlin M. Braitsch et al. DEVELOPMENTAL BIOLOGY
- Differential DNase I hypersensitivity reveals factor-dependent chromatin dynamics
- (2012) Housheng Hansen He et al. GENOME RESEARCH
- ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia
- (2012) S. G. Landt et al. GENOME RESEARCH
- The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis
- (2012) LANCET
- DNase I sensitivity QTLs are a major determinant of human expression variation
- (2012) Jacob F. Degner et al. NATURE
- Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease
- (2012) Luke Jostins et al. NATURE
- Common genetic variants at the 11q13.3 renal cancer susceptibility locus influence binding of HIF to an enhancer of cyclin D1 expression
- (2012) Johannes Schödel et al. NATURE GENETICS
- Large-scale association analysis identifies new risk loci for coronary artery disease
- (2012) Panos Deloukas et al. NATURE GENETICS
- Genome-wide association study in Han Chinese identifies four new susceptibility loci for coronary artery disease
- (2012) Xiangfeng Lu et al. NATURE GENETICS
- Powerful Identification of Cis-regulatory SNPs in Human Primary Monocytes Using Allele-Specific Gene Expression
- (2012) Jonas Carlsson Almlöf et al. PLoS One
- Systematic Localization of Common Disease-Associated Variation in Regulatory DNA
- (2012) M. T. Maurano et al. SCIENCE
- Epigenetic Control of Smooth Muscle Cell Differentiation and Phenotypic Switching in Vascular Development and Disease
- (2011) Matthew R. Alexander et al. Annual Review of Physiology
- Macrophages in the Pathogenesis of Atherosclerosis
- (2011) Kathryn J. Moore et al. CELL
- Leiomodin 1, a New Serum Response Factor-dependent Target Gene Expressed Preferentially in Differentiated Smooth Muscle Cells
- (2011) Vivek Nanda et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Transcription Factor AP1 Potentiates Chromatin Accessibility and Glucocorticoid Receptor Binding
- (2011) Simon C. Biddie et al. MOLECULAR CELL
- Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease
- (2011) Heribert Schunkert et al. NATURE GENETICS
- A genome-wide association study in Europeans and South Asians identifies five new loci for coronary artery disease
- (2011) John F Peden et al. NATURE GENETICS
- Transcriptome genetics using second generation sequencing in a Caucasian population
- (2010) Stephen B. Montgomery et al. NATURE
- From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus
- (2010) Kiran Musunuru et al. NATURE
- Targeted deletion of the 9p21 non-coding coronary artery disease risk interval in mice
- (2010) Axel Visel et al. NATURE
- A map of open chromatin in human pancreatic islets
- (2010) Kyle J Gaulton et al. NATURE GENETICS
- Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci
- (2010) Andre Franke et al. NATURE GENETICS
- Variation in Transcription Factor Binding Among Humans
- (2010) M. Kasowski et al. SCIENCE
- Multi-Organ Expression Profiling Uncovers a Gene Module in Coronary Artery Disease Involving Transendothelial Migration of Leukocytes and LIM Domain Binding 2: The Stockholm Atherosclerosis Gene Expression (STAGE) Study
- (2009) Sara Hägg et al. PLoS Genetics
- Genome-wide association studies for complex traits: consensus, uncertainty and challenges
- (2008) Mark I. McCarthy et al. NATURE REVIEWS GENETICS
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started