ISPD produces CDP-ribitol used by FKTN and FKRP to transfer ribitol phosphate onto α-dystroglycan

Identification of a Post-translational Modification with Ribitol-Phosphate and Its Defect in Muscular Dystrophy

(2016) Motoi Kanagawa et al.   Cell Reports

Human ISPD Is a Cytidyltransferase Required for Dystroglycan O-Mannosylation

(2015) Moniek Riemersma et al.   CHEMISTRY & BIOLOGY

Matriglycan: a novel polysaccharide that links dystroglycan to the basement membrane

(2015) T. Yoshida-Moriguchi et al.   GLYCOBIOLOGY

Disease mutations in CMP-sialic acid transporter SLC35A1 result in abnormal  -dystroglycan O-mannosylation, independent from sialic acid

(2015) M. Riemersma et al.   HUMAN MOLECULAR GENETICS

Lipoteichoic Acid Synthesis and Function in Gram-Positive Bacteria

(2014) Matthew G. Percy et al.   Annual Review of Microbiology

Identification of TP53-induced glycolysis and apoptosis regulator (TIGAR) as the phosphoglycolate-independent 2,3-bisphosphoglycerate phosphatase

(2014) Isabelle Gerin et al.   BIOCHEMICAL JOURNAL

Glycobiology of  -dystroglycan and muscular dystrophy

(2014) T. Endo   JOURNAL OF BIOCHEMISTRY

Multiple Phenotypes in Phosphoglucomutase 1 Deficiency

(2014) Laura C. Tegtmeyer et al.   NEW ENGLAND JOURNAL OF MEDICINE

Mutations in B3GALNT2 Cause Congenital Muscular Dystrophy and Hypoglycosylation of α-Dystroglycan

(2013) Elizabeth Stevens et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Mutations in GDP-Mannose Pyrophosphorylase B Cause Congenital and Limb-Girdle Muscular Dystrophies Associated with Hypoglycosylation of α-Dystroglycan

(2013) Keren J. Carss et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Wall Teichoic Acids of Gram-Positive Bacteria

(2013) Stephanie Brown et al.   Annual Review of Microbiology

GTDC2 modifies O-mannosylated α-dystroglycan in the endoplasmic reticulum to generate N-acetyl glucosamine epitopes reactive with CTD110.6 antibody

(2013) Mitsutaka Ogawa et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

ISPD gene mutations are a common cause of congenital and limb-girdle muscular dystrophies

(2013) Sebahattin Cirak et al.   BRAIN

Dissecting the Molecular Basis of the Role of the O-Mannosylation Pathway in Disease: α-Dystroglycan and Forms of Muscular Dystrophy

(2013) David Live et al.   CHEMBIOCHEM

LARGE glycans on dystroglycan function as a tunable matrix scaffold to prevent dystrophy

(2013) Matthew M. Goddeeris et al.   NATURE

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols

Flow Cytometry for the Analysis of α-Dystroglycan Glycosylation in Fibroblasts from Patients with Dystroglycanopathies

(2013) Elizabeth Stevens et al.   PLoS One

Protein O-mannosylation is crucial for E-cadherin-mediated cell adhesion

(2013) M. Lommel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mining the O-mannose glycoproteome reveals cadherins as major O-mannosylated glycoproteins

(2013) M. B. Vester-Christensen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SGK196 Is a Glycosylation-Specific O-Mannose Kinase Required for Dystroglycan Function

(2013) T. Yoshida-Moriguchi et al.   SCIENCE

AGO61-dependent GlcNAc modification primes the formation of functional glycans on α-dystroglycan

(2013) Hirokazu Yagi et al.   Scientific Reports

Exome Sequencing and Functional Validation in Zebrafish Identify GTDC2 Mutations as a Cause of Walker-Warburg Syndrome

(2012) M. Chiara Manzini et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Identification of Mutations in TMEM5 and ISPD as a Cause of Severe Cobblestone Lissencephaly

(2012) Sandrine Vuillaumier-Barrot et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Detection of the dystroglycanopathy protein, fukutin, using a new panel of site-specific monoclonal antibodies

(2012) Tracy A. Lynch et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

O-Mannose and O–N-acetyl galactosamine glycosylation of mammalian α-dystroglycan is conserved in a region-specific manner

(2012) Alejandro Gomez Toledo et al.   GLYCOBIOLOGY

O-LinkedN,N′-Diacetyllactosamine (LacdiNAc)-modified Glycans in Extracellular Matrix Glycoproteins Are Specifically Phosphorylated at SubterminalN-Acetylglucosamine

(2012) Isabelle Breloy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neurofascin 186 Is O-Mannosylated within and Outside of the Mucin Domain

(2012) Sandra Pacharra et al.   JOURNAL OF PROTEOME RESEARCH

Biosynthesis of Teichoic Acids in Streptococcus pneumoniae and Closely Related Species: Lessons from Genomes

(2012) Dalia Denapaite et al.   Microbial Drug Resistance

Mutations in ISPD cause Walker-Warburg syndrome and defective glycosylation of α-dystroglycan

(2012) Tony Roscioli et al.   NATURE GENETICS

ISPD loss-of-function mutations disrupt dystroglycan O-mannosylation and cause Walker-Warburg syndrome

(2012) Tobias Willer et al.   NATURE GENETICS

Dystroglycan Function Requires Xylosyl- and Glucuronyltransferase Activities of LARGE

(2012) K.-i. Inamori et al.   SCIENCE

Biochemistry of the non-mevalonate isoprenoid pathway

(2011) Tobias Gräwert et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Location, synthesis and function of glycolipids and polyglycerolphosphate lipoteichoic acid in Gram-positive bacteria of the phylum Firmicutes

(2011) Nathalie T. Reichmann et al.   FEMS MICROBIOLOGY LETTERS

Glycomic Analyses of Mouse Models of Congenital Muscular Dystrophy

(2011) Stephanie H. Stalnaker et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The FGGY Carbohydrate Kinase Family: Insights into the Evolution of Functional Specificities

(2011) Ying Zhang et al.   PLoS Computational Biology

O-Mannosyl Phosphorylation of Alpha-Dystroglycan Is Required for Laminin Binding

(2010) T. Yoshida-Moriguchi et al.   SCIENCE

Molecular Cloning and Expression of a Novel Cholinephosphotransferase Involved in Glycoglycerophospholipid Biosynthesis of Mycoplasma fermentans

(2009) Noriko Ishida et al.   CURRENT MICROBIOLOGY

Novel endo- -N-acetylgalactosaminidases with broader substrate specificity

(2008) D. Koutsioulis et al.   GLYCOBIOLOGY

Synthesis of CDP-Activated Ribitol for Teichoic Acid Precursors in Streptococcus pneumoniae

(2008) S. Baur et al.   JOURNAL OF BACTERIOLOGY

Different Pathways of Choline Metabolism in Two Choline-Independent Strains of Streptococcus pneumoniae and Their Impact on Virulence

(2008) A. S. Kharat et al.   JOURNAL OF BACTERIOLOGY