Endothelial-specific inhibition of NF-κB enhances functional haematopoiesis

Inflammatory cytokines provide both infection-responsive and developmental signals for blood development: Lessons from the zebrafish

(2016) Chris Hall et al.   MOLECULAR IMMUNOLOGY

Angiocrine functions of organ-specific endothelial cells

(2016) Shahin Rafii et al.   NATURE

Chronic interleukin-1 exposure drives haematopoietic stem cells towards precocious myeloid differentiation at the expense of self-renewal

(2016) Eric M. Pietras et al.   NATURE CELL BIOLOGY

Making sense of hematopoietic stem cell niches

(2015) P. E. Boulais et al.   BLOOD

Vascular Platform to Define Hematopoietic Stem Cell Factors and Enhance Regenerative Hematopoiesis

(2015) Michael G. Poulos et al.   Stem Cell Reports

Proinflammatory Signaling Regulates Hematopoietic Stem Cell Emergence

(2014) Raquel Espín-Palazón et al.   CELL

Notch-Dependent Repression of miR-155 in the Bone Marrow Niche Regulates Hematopoiesis in an NF-κB-Dependent Manner

(2014) Lin Wang et al.   Cell Stem Cell

Conversion of Danger Signals into Cytokine Signals by Hematopoietic Stem and Progenitor Cells for Regulation of Stress-Induced Hematopoiesis

(2014) Jimmy L. Zhao et al.   Cell Stem Cell

The analysis, roles and regulation of quiescence in hematopoietic stem cells

(2014) A. Nakamura-Ishizu et al.   DEVELOPMENT

Pro-inflammatory cytokines: Emerging players regulating HSC function in normal and diseased hematopoiesis

(2014) Cristina Mirantes et al.   EXPERIMENTAL CELL RESEARCH

Inflammatory signaling regulates embryonic hematopoietic stem and progenitor cell production

(2014) Yan Li et al.   GENES & DEVELOPMENT

The bone marrow niche for haematopoietic stem cells

(2014) Sean J. Morrison et al.   NATURE

Megakaryocytes regulate hematopoietic stem cell quiescence through CXCL4 secretion

(2014) Ingmar Bruns et al.   NATURE MEDICINE

New paradigms in inflammatory signaling in vascular endothelial cells

(2013) Lei Xiao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Umbilical cord blood transplantation: the first 25 years and beyond

(2013) K. K. Ballen et al.   BLOOD

Deletion of the NF- B subunit p65/RelA in the hematopoietic compartment leads to defects in hematopoietic stem cell function

(2013) S. J. Stein et al.   BLOOD

Combined mutation ofVhlandTrp53causes renal cysts and tumours in mice

(2013) Joachim Albers et al.   EMBO Molecular Medicine

Haematopoietic stem cells and early lymphoid progenitors occupy distinct bone marrow niches

(2013) Lei Ding et al.   NATURE

M-CSF instructs myeloid lineage fate in single haematopoietic stem cells

(2013) Noushine Mossadegh-Keller et al.   NATURE

Endothelial Jagged-1 Is Necessary for Homeostatic and Regenerative Hematopoiesis

(2013) Michael G. Poulos et al.   Cell Reports

NF-κB subunit specificity in hemopoiesis

(2012) Steve Gerondakis et al.   IMMUNOLOGICAL REVIEWS

Endothelial and perivascular cells maintain haematopoietic stem cells

(2012) Lei Ding et al.   NATURE

Embryonic origin of the adult hematopoietic system: advances and questions

(2011) A. Medvinsky et al.   DEVELOPMENT

Non-canonical NF-κB signaling activation and regulation: principles and perspectives

(2011) Bahram Razani et al.   IMMUNOLOGICAL REVIEWS

Tumor necrosis factor restricts hematopoietic stem cell activity in mice: involvement of two distinct receptors

(2011) Cornelis J.H. Pronk et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Crosstalk in NF-κB signaling pathways

(2011) Andrea Oeckinghaus et al.   NATURE IMMUNOLOGY

NF- B dysregulation in microRNA-146a-deficient mice drives the development of myeloid malignancies

(2011) J. L. Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Endothelial Dysfunction after Hematopoietic Stem Cell Transplantation: Role of the Conditioning Regimen and the Type of Transplantation

(2010) Marta Palomo et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Endothelial Cells Are Essential for the Self-Renewal and Repopulation of Notch-Dependent Hematopoietic Stem Cells

(2010) Jason M. Butler et al.   Cell Stem Cell

Quiescent haematopoietic stem cells are activated by IFN-γ in response to chronic infection

(2010) Megan T. Baldridge et al.   NATURE

Angiocrine factors from Akt-activated endothelial cells balance self-renewal and differentiation of haematopoietic stem cells

(2010) Hideki Kobayashi et al.   NATURE CELL BIOLOGY

TNF-α Regulates the Effects of Irradiation in the Mouse Bone Marrow Microenvironment

(2010) Ana Sofia Cachaço et al.   PLoS One

Endothelial progenitor cell infusion induces hematopoietic stem cell reconstitution in vivo

(2009) A. B. Salter et al.   BLOOD

Engraftment and Reconstitution of Hematopoiesis Is Dependent on VEGFR2-Mediated Regeneration of Sinusoidal Endothelial Cells

(2009) Andrea T. Hooper et al.   Cell Stem Cell

ELDA: Extreme limiting dilution analysis for comparing depleted and enriched populations in stem cell and other assays

(2009) Yifang Hu et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Bone-marrow adipocytes as negative regulators of the haematopoietic microenvironment

(2009) Olaia Naveiras et al.   NATURE

Endothelial Cell-Specific NF-κB Inhibition Protects Mice from Atherosclerosis

(2008) Ralph Gareus et al.   Cell Metabolism

Bone marrow sinusoidal endothelial cells undergo nonapoptotic cell death and are replaced by proliferating sinusoidal cells in situ to maintain the vascular niche following lethal irradiation

(2008) Xiao-Miao Li et al.   EXPERIMENTAL HEMATOLOGY

Intrinsic and extrinsic control of haematopoietic stem-cell self-renewal

(2008) Leonard I. Zon   NATURE

Origin and physiological roles of inflammation

(2008) Ruslan Medzhitov   NATURE

Is NF-κB a good target for cancer therapy? Hopes and pitfalls

(2008) Véronique Baud et al.   NATURE REVIEWS DRUG DISCOVERY

The Contribution of Endothelial Activation and Injury to End-Organ Toxicity following Allogeneic Hematopoietic Stem Cell Transplantation

(2007) Kenneth R. Cooke et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION