PAK proteins and YAP-1 signalling downstream of integrin beta-1 in myofibroblasts promote liver fibrosis
出版年份 2016 全文链接
标题
PAK proteins and YAP-1 signalling downstream of integrin beta-1 in myofibroblasts promote liver fibrosis
作者
关键词
-
出版物
Nature Communications
Volume 7, Issue -, Pages 12502
出版商
Springer Nature
发表日期
2016-08-18
DOI
10.1038/ncomms12502
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Pathobiology of liver fibrosis: a translational success story
- (2015) Youngmin A Lee et al. GUT
- The Hippo pathway effector YAP controls mouse hepatic stellate cell activation
- (2015) Inge Mannaerts et al. JOURNAL OF HEPATOLOGY
- High-yield and high-purity isolation of hepatic stellate cells from normal and fibrotic mouse livers
- (2015) Ingmar Mederacke et al. Nature Protocols
- Integrin α11β1 regulates cancer stromal stiffness and promotes tumorigenicity and metastasis in non-small cell lung cancer
- (2015) R Navab et al. ONCOGENE
- Liver cirrhosis mortality in 187 countries between 1980 and 2010: a systematic analysis
- (2014) Ali A Mokdad et al. BMC Medicine
- Epimorphin Alters the Inhibitory Effects of SOX9 on Mmp13 in Activated Hepatic Stellate Cells
- (2014) James Pritchett et al. PLoS One
- Viral Small T Oncoproteins Transform Cells by Alleviating Hippo-Pathway-Mediated Inhibition of the YAP Proto-oncogene
- (2014) Hung Thanh Nguyen et al. Cell Reports
- Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts
- (2013) Fernando Calvo et al. NATURE CELL BIOLOGY
- Targeting of αv integrin identifies a core molecular pathway that regulates fibrosis in several organs
- (2013) Neil C Henderson et al. NATURE MEDICINE
- Therapy for Fibrotic Diseases: Nearing the Starting Line
- (2013) S. L. Friedman et al. Science Translational Medicine
- Fate tracing reveals hepatic stellate cells as dominant contributors to liver fibrosis independent of its aetiology
- (2013) Ingmar Mederacke et al. Nature Communications
- Mesalamine modulates intercellular adhesion through inhibition of p-21 activated kinase-1
- (2012) Vineeta Khare et al. BIOCHEMICAL PHARMACOLOGY
- Integrin-mediated regulation of TGFβ in fibrosis
- (2012) Neil C. Henderson et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- α11 integrin stimulates myofibroblast differentiation in diabetic cardiomyopathy
- (2012) Ilana Talior-Volodarsky et al. CARDIOVASCULAR RESEARCH
- Paracrine signalling in colorectal liver metastases involving tumor cell-derived PDGF-C and hepatic stellate cell-derived PAK-2
- (2012) Obul R. Bandapalli et al. CLINICAL & EXPERIMENTAL METASTASIS
- Deactivation of Hepatic Stellate Cells During Liver Fibrosis Resolution in Mice
- (2012) Juliane S. Troeger et al. GASTROENTEROLOGY
- Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP
- (2012) Y. Liu-Chittenden et al. GENES & DEVELOPMENT
- Osteopontin is a novel downstream target of SOX9 with diagnostic implications for progression of liver fibrosis in humans
- (2012) James Pritchett et al. HEPATOLOGY
- Specific β-containing Integrins Exert Differential Control on Proliferation and Two-dimensional Collective Cell Migration in Mammary Epithelial Cells
- (2012) Alexa I. Jeanes et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Myofibroblasts revert to an inactive phenotype during regression of liver fibrosis
- (2012) T. Kisseleva et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Role of YAP/TAZ in mechanotransduction
- (2011) Sirio Dupont et al. NATURE
- Current status of novel antifibrotic therapies in patients with chronic liver disease
- (2011) Michal Cohen-Naftaly et al. Therapeutic Advances in Gastroenterology
- Prevalence of liver fibrosis and risk factors in a general population using non-invasive biomarkers (FibroTest)
- (2010) Thierry Poynard et al. BMC GASTROENTEROLOGY
- PAK1 as a therapeutic target
- (2010) Julia V Kichina et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- Expression of integrin 1 by fibroblasts is required for tissue repair in vivo
- (2010) S. Liu et al. JOURNAL OF CELL SCIENCE
- PAK1 and PAK2 have different roles in HGF-induced morphological responses
- (2009) Michael D. Bright et al. CELLULAR SIGNALLING
- An Isoform-Selective, Small-Molecule Inhibitor Targets the Autoregulatory Mechanism of p21-Activated Kinase
- (2008) Sean W. Deacon et al. CHEMISTRY & BIOLOGY
- TEAD mediates YAP-dependent gene induction and growth control
- (2008) B. Zhao et al. GENES & DEVELOPMENT
- Ectopic SOX9 Mediates Extracellular Matrix Deposition Characteristic of Organ Fibrosis
- (2008) Karen Piper Hanley et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Pak1 and Pak2 Mediate Tumor Cell Invasion through Distinct Signaling Mechanisms
- (2008) S. J. Coniglio et al. MOLECULAR AND CELLULAR BIOLOGY
- Yap1 Phosphorylation by c-Abl Is a Critical Step in Selective Activation of Proapoptotic Genes in Response to DNA Damage
- (2008) Dan Levy et al. MOLECULAR CELL
- ERK5 differentially regulates PDGF-induced proliferation and migration of hepatic stellate cells
- (2007) Elisabetta Rovida et al. JOURNAL OF HEPATOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started