Intracellular mGluR5 plays a critical role in neuropathic pain

Blockade of spinal glutamate recycling produces paradoxical antinociception in rats with orofacial inflammatory pain

(2015) Kui Y. Yang et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Neuronal Activity and Glutamate Uptake Decrease Mitochondrial Mobility in Astrocytes and Position Mitochondria Near Glutamate Transporters

(2014) J. G. Jackson et al.   JOURNAL OF NEUROSCIENCE

Intracellular mGluR5 Can Mediate Synaptic Plasticity in the Hippocampus

(2014) C. A. Purgert et al.   JOURNAL OF NEUROSCIENCE

Subcellular localization of coagulation factor II receptor-like 1 in neurons governs angiogenesis

(2014) Jean-Sébastien Joyal et al.   NATURE MEDICINE

Nuclear Localization of α1A‐Adrenergic Receptors Is Required for Signaling in Cardiac Myocytes: An “Inside‐Out” α1‐AR Signaling Pathway

(2014) Steven C. Wu et al.   Journal of the American Heart Association

Spinal synaptic scaffolding protein Homer 1b/c regulates CREB phosphorylation and c-fos activation induced by inflammatory pain in rats

(2013) Yong-Xing Yao et al.   NEUROSCIENCE LETTERS

Psychiatric Drugs Bind to Classical Targets Within Early Exocytotic Pathways: Therapeutic Effects

(2012) Henry A. Lester et al.   BIOLOGICAL PSYCHIATRY

Preso1 dynamically regulates group I metabotropic glutamate receptors

(2012) Jia-Hua Hu et al.   NATURE NEUROSCIENCE

Transient nerve root compression load and duration differentially mediate behavioral sensitivity and associated spinal astrocyte activation and mGLuR5 expression

(2012) K.J. Nicholson et al.   NEUROSCIENCE

Effect of Inhibition of Spinal Cord Glutamate Transporters on Inflammatory Pain Induced by Formalin and Complete Freundʼs Adjuvant

(2011) Myron Yaster et al.   ANESTHESIOLOGY

STIM Proteins and the Endoplasmic Reticulum-Plasma Membrane Junctions

(2011) Silvia Carrasco et al.   Annual Review of Biochemistry

Activation of Intracellular Metabotropic Glutamate Receptor 5 in Striatal Neurons Leads to Up-regulation of Genes Associated with Sustained Synaptic Transmission Including Arc/Arg3.1 Protein

(2011) Vikas Kumar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Co-compartmentalization of the Astroglial Glutamate Transporter, GLT-1, with Glycolytic Enzymes and Mitochondria

(2011) E. N. Genda et al.   JOURNAL OF NEUROSCIENCE

G protein-coupled receptor signalling in the cardiac nuclear membrane: evidence and possible roles in physiological and pathophysiological function

(2011) Artavazd Tadevosyan et al.   JOURNAL OF PHYSIOLOGY-LONDON

Intracellular Metabotropic Glutamate Receptor 5 (mGluR5) Activates Signaling Cascades Distinct from Cell Surface Counterparts

(2009) Yuh-Jiin I. Jong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Metabotropic Glutamate Receptor Subtype 5 Antagonist Fenobam Is Analgesic and Has Improved in Vivo Selectivity Compared with the Prototypical Antagonist 2-Methyl-6-(phenylethynyl)-pyridine

(2009) M. C. Montana et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Spinal cord mechanisms of pain

(2008) R. D’Mello et al.   BRITISH JOURNAL OF ANAESTHESIA

Activated Nuclear Metabotropic Glutamate Receptor mGlu5 Couples to Nuclear Gq/11Proteins to Generate Inositol 1,4,5-Trisphosphate-mediated Nuclear Ca2+Release

(2008) Vikas Kumar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

G Protein-Coupled Receptors in and on the Cell Nucleus: A New Signaling Paradigm?

(2008) BENOIT BOIVIN et al.   JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

Metabotropic Glutamate Receptors in Glial Cells

(2008) Simona D’Antoni et al.   NEUROCHEMICAL RESEARCH

Neuroprotective activity of the mGluR5 antagonists MPEP and MTEP against acute excitotoxicity differs and does not reflect actions at mGluR5 receptors

(2005) Paul M Lea et al.   BRITISH JOURNAL OF PHARMACOLOGY