Article
Oncology
Xiaojun Xu, Xun Sun, Ling Ma, Huangqi Zhang, Wenbin Ji, Xiaotian Xia, Xiaoli Lan
Summary: This study aimed to investigate the feasibility of predicting progression-free survival (PFS) in breast cancer patients using pretreatment F-18-fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) radiomics signature and clinical parameters. The study found that the integrated clinical-radiomics (ICR) model, which combined clinical parameters and preoperative FDG PET/CT imaging, was able to independently predict PFS in breast cancer patients, and was superior to the clinical model alone and rad-score alone.
FRONTIERS IN ONCOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Virginia Liberini, Michael Messerli, Lars Husmann, Ken Kudura, Hannes Grunig, Alexander Maurer, Stephan Skawran, Erika Orita, Daniele A. Pizzuto, Desiree Deandreis, Reinhard Dummer, Joanna Mangana, Daniela Mihic-Probst, Niels Rupp, Martin W. Huellner
Summary: BSREM detects significantly more ITM than OSEM, with higher SUVmax, higher TBR, and less blurring. BSREM is particularly helpful in small and less avid lesions, which are more often missed with OSEM.
EUROPEAN RADIOLOGY
(2021)
Article
Urology & Nephrology
Sarah R. Ottenhof, Rosa S. Djajadiningrat, Michelle W. J. Versleijen, Maarten L. Donswijk, Vincent van der Noort, Oscar R. Brouwer, Niels M. Graafland, Erik Vegt, Simon Horenblas
Summary: FDG-PET/CT has high diagnostic value for staging pelvic lymph nodes and detecting distant metastases in high-risk penile cancer patients. It has high sensitivity and negative predictive value for pelvic lymph node staging, as well as a high positive predictive value for the detection of distant metastases.
EUROPEAN UROLOGY FOCUS
(2022)
Article
Medicine, General & Internal
Haejun Lee, Kyung-Hoon Hwang, Kwang An Kwon
Summary: Background: Colon and rectal cancers are among the top five cancers worldwide. Early detection is crucial for effective treatment. FDG PET parameters can assess malignant lesions in the colon.
WORLD JOURNAL OF CLINICAL CASES
(2022)
Article
Cardiac & Cardiovascular Systems
Ayako Ishikita, Ichiro Sakamoto, Kenichiro Yamamura, Shintaro Umemoto, Hazumu Nagata, Yoshiyuki Kitamura, Yuzo Yamasaki, Hiromichi Sonoda, Hideki Tatewaki, Akira Shiose, Hiroyuki Tsutsui
Summary: This study retrospectively studied 22 patients with ACHD, confirming the additional diagnostic value of F-18-FDG PET/CT assessment for ACHD-associated IE. Right-sided IE was more common, and F-18-FDG PET/CT was helpful in detecting right-sided lesions.
CIRCULATION JOURNAL
(2021)
Review
Radiology, Nuclear Medicine & Medical Imaging
Seyed Ali Mirshahvalad, Aruz Mesci, Vanessa Murad, Andres Kohan, Claudia Ortega, Patrick Veit-Haibach, Ur Metser
Summary: This study conducted a meta-analysis to evaluate the diagnostic and prognostic value of PET in anal canal cancer patients. The results showed that PET had high sensitivity and specificity in distinguishing T3/T4 stages and detecting metastatic disease. PET also showed good sensitivity and specificity in therapy response assessment. Furthermore, pre-treatment total metabolic tumour volume was found to be predictive of survival, and complete metabolic response was associated with better prognosis. Overall, PET may be a valuable tool in therapy planning and prognostic assessment for anal canal cancer.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Ogun Bulbul, Hande Melike Bulbul, Kemal Can Tertemiz, Gamze Capa Kaya, Duygu Gurel, Emine Cagnur Ulukus, Naciye Sinem Gezer
Summary: Texture analysis and machine learning methods are useful in distinguishing between benign and malignant tissues and determining lung cancer subtypes based on lymph node analysis. The algorithms used in F-18 fluorodeoxyglucose positron emission tomography/computed tomography and contrast-enhanced computed tomography showed good sensitivity, specificity, and AUC values in differentiating lymph node metastases.
Review
Oncology
Federica Matteucci, Giovanni Paganelli, Giovanni Martinelli, Claudio Cerchione
Summary: Recent advances in the diagnosis and treatment of multiple myeloma have emphasized the importance of imaging methods, particularly PET/CT, in providing accurate information for disease localization, prognosis, and therapy response evaluation. While 18F-FDG tracer is commonly used and has high sensitivity, limitations such as physiological uptake in the bone marrow and brain have prompted research on other PET tracers for improved accuracy in multiple myeloma management.
FRONTIERS IN ONCOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Dan Shao, Qiang Gao, You Cheng, Dong-Yang Du, Si-Yun Wang, Shu-Xia Wang
Summary: The study demonstrates that F-18-FDG PET/CT can predict the survival of patients with primary tracheal malignant tumors. Patients with higher metabolic tumor volume (MTV) and total lesion glycolysis (TLG) on PET/CT scans, squamous cell carcinoma, and non-E1 surgeries are more likely to have reduced overall survival.
KOREAN JOURNAL OF RADIOLOGY
(2021)
Review
Oncology
Sungmin Woo, Anton S. Becker, Richard K. G. Do, Heiko Schoder, Hedvig Hricak, H. Alberto Vargas
Summary: FDG-PET or PET/CT had a meaningful impact on the management of patients with CUP, with approximately a third of patients having their management changed as a result, mainly due to detection of the primary site. This finding was consistent across numerous subgroups.
EUROPEAN JOURNAL OF CANCER
(2021)
Article
Medicine, General & Internal
Haejun Lee, Yoo Seung Chung, Joon-Hyop Lee, Ki-Young Lee, Kyung-Hoon Hwang
Summary: This study aimed to distinguish malignant and benign diseases of hypermetabolic thyroid tumors using F-18 FDG PET-CT parameters and identified SUVmax as the best parameter. Unexpected hypermetabolic thyroid tumors with an SUVmax above the cut-off value of 8.5 may have a greater than 70% chance of malignancy, therefore further assessment is required.
WORLD JOURNAL OF CLINICAL CASES
(2022)
Review
Radiology, Nuclear Medicine & Medical Imaging
K. S. M. van der Geest, G. Treglia, A. W. J. M. Glaudemans, E. Brouwer, F. Jamar, R. H. J. A. Slart, O. Gheysens
Summary: [18F]FDG-PET/CT scanning can effectively diagnose polymyalgia rheumatica by identifying significant uptake of FDG at specific anatomic sites. The technique shows promise as an important diagnostic tool for patients with suspected PMR, but standardized interpretation criteria and procedural recommendations are necessary for its use.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
(2021)
Review
Radiology, Nuclear Medicine & Medical Imaging
Benjamin Koa, Austin J. Borja, Mahmoud Aly, Sayuri Padmanabhan, Joseph Tran, Vincent Zhang, Chaitanya Rojulpote, Sheila K. Pierson, Mark-Avery Tamakloe, Johnson S. Khor, Thomas J. Werner, David C. Fajgenbaum, Abass Alavi, Mona-Elisabeth Revheim
Summary: Castleman disease is a rare hematologic condition involving lymphadenopathy and clinical abnormalities, classified into UCD and MCD; MCD is further divided based on etiological driver; FDG-PET/CT plays an important role in differential diagnosis and monitoring treatment responses.
INSIGHTS INTO IMAGING
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Kailin Qiao, Xueting Qin, Shuai Fu, Jiazhong Ren, Jing Jia, Xinying Hu, Yuanyuan Tao, Shuanghu Yuan, Yuchun Wei
Summary: The uptake of [F-18]AlF-NOTA-FAPI-04 and [F-18]FDG imaging tracers varies in malignant and inflammatory lung lesions, with lower uptake observed in inflammatory lesions. This difference in uptake can be valuable for distinguishing between malignancy and various inflammatory findings.
EUROPEAN RADIOLOGY
(2023)
Review
Medicine, General & Internal
Haejun Lee, Kyung-Hoon Hwang
Summary: Approximately 60% of incidentally observed focal F-18 FDG uptake in the colon/rectum, thyroid, and prostate were found to be malignant. Among the several PET parameters, SUVmax was superior in distinguishing between malignant/premalignant and benign lesions.
WORLD JOURNAL OF CLINICAL CASES
(2022)