Study Design and Rationale for the Phase 3 Clinical Development Program of Enobosarm, a Selective Androgen Receptor Modulator, for the Prevention and Treatment of Muscle Wasting in Cancer Patients (POWER Trials)
出版年份 2016 全文链接
标题
Study Design and Rationale for the Phase 3 Clinical Development Program of Enobosarm, a Selective Androgen Receptor Modulator, for the Prevention and Treatment of Muscle Wasting in Cancer Patients (POWER Trials)
作者
关键词
Muscle wasting, Sarcopenia, Selective androgen receptor modulator, Cachexia, Non-small-cell lung cancer, Enobosarm, Cachexia treatment, Cachexia therapy
出版物
Current Oncology Reports
Volume 18, Issue 6, Pages -
出版商
Springer Nature
发表日期
2016-05-02
DOI
10.1007/s11912-016-0522-0
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- A phase III randomized study comparing the effects of oxandrolone (Ox) and megestrol acetate (Meg) on lean body mass (LBM), weight (wt) and quality of life (QOL) in patients with solid tumors and weight loss receiving chemotherapy
- (2017) G. J. Lesser et al. JOURNAL OF CLINICAL ONCOLOGY
- A population-based approach to define body-composition phenotypes
- (2014) Carla MM Prado et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Lean Tissue Imaging
- (2014) Carla M. M. Prado et al. JOURNAL OF PARENTERAL AND ENTERAL NUTRITION
- Central tenet of cancer cachexia therapy: do patients with advanced cancer have exploitable anabolic potential?
- (2013) Carla M Prado et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Screening for Osteoporosis in Men: A Systematic Review for an American College of Physicians Guideline
- (2013) Hau Liu et al. ANNALS OF INTERNAL MEDICINE
- Assessment of Nutritional Status in Cancer – The Relationship Between Body Composition and Pharmacokinetics
- (2013) Carla Prado et al. Anti-Cancer Agents in Medicinal Chemistry
- Body composition in chemotherapy
- (2013) Carla M.M. Prado CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE
- Effects of enobosarm on muscle wasting and physical function in patients with cancer: a double-blind, randomised controlled phase 2 trial
- (2013) Adrian S Dobs et al. LANCET ONCOLOGY
- Cancer Cachexia: Mediators, Signaling, and Metabolic Pathways
- (2012) Kenneth C.H. Fearon et al. Cell Metabolism
- Sarcopenic obesity: A Critical appraisal of the current evidence
- (2012) C.M.M. Prado et al. CLINICAL NUTRITION
- Terminology in cancer cachexia
- (2012) Neil MacDonald CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE
- Definition and classification of cancer cachexia: an international consensus
- (2011) Kenneth Fearon et al. LANCET ONCOLOGY
- The ACT-ONE trial, a multicentre, randomised, double-blind, placebo-controlled, dose-finding study of the anabolic/catabolic transforming agent, MT-102 in subjects with cachexia related to stage III and IV non-small cell lung cancer and colorectal cancer:
- (2011) Andrew J. Stewart Coats et al. Journal of Cachexia Sarcopenia and Muscle
- The selective androgen receptor modulator GTx-024 (enobosarm) improves lean body mass and physical function in healthy elderly men and postmenopausal women: results of a double-blind, placebo-controlled phase II trial
- (2011) James T. Dalton et al. Journal of Cachexia Sarcopenia and Muscle
- Skeletal muscle loss: cachexia, sarcopenia, and inactivity
- (2010) William J Evans AMERICAN JOURNAL OF CLINICAL NUTRITION
- Body composition in patients with non−small cell lung cancer: a contemporary view of cancer cachexia with the use of computed tomography image analysis
- (2010) Vickie E Baracos et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Association of Skeletal Muscle Wasting With Treatment With Sorafenib in Patients With Advanced Renal Cell Carcinoma: Results From a Placebo-Controlled Study
- (2010) Sami Antoun et al. JOURNAL OF CLINICAL ONCOLOGY
- Early Palliative Care for Patients with Metastatic Non–Small-Cell Lung Cancer
- (2010) Jennifer S. Temel et al. NEW ENGLAND JOURNAL OF MEDICINE
- Randomized Phase III Clinical Trial of Five Different Arms of Treatment in 332 Patients with Cancer Cachexia
- (2010) G. Mantovani et al. ONCOLOGIST
- Associations of the Stair Climb Power Test With Muscle Strength and Functional Performance in People With Chronic Obstructive Pulmonary Disease: A Cross-Sectional Study
- (2010) M. Roig et al. PHYSICAL THERAPY
- Sarcopenia as a Determinant of Chemotherapy Toxicity and Time to Tumor Progression in Metastatic Breast Cancer Patients Receiving Capecitabine Treatment
- (2009) C. M.M. Prado et al. CLINICAL CANCER RESEARCH
- Nonsteroidal Selective Androgen Receptor Modulators (SARMs): Dissociating the Anabolic and Androgenic Activities of the Androgen Receptor for Therapeutic Benefit
- (2009) Michael L. Mohler et al. JOURNAL OF MEDICINAL CHEMISTRY
- Phase II nonrandomized study of the efficacy and safety of COX-2 inhibitor celecoxib on patients with cancer cachexia
- (2009) Giovanni Mantovani et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- What is a meaningful change in physical performance? Findings from a clinical trial in older adults (the LIFE-P study)
- (2009) S. Kwon et al. Journal of Nutrition Health & Aging
- Sustained-release oral fampridine in multiple sclerosis: a randomised, double-blind, controlled trial
- (2009) Andrew D Goodman et al. LANCET
- The emerging role of computerized tomography in assessing cancer cachexia
- (2009) Carla MM Prado et al. Current Opinion in Supportive and Palliative Care
- Cachexia: A new definition
- (2008) William J. Evans et al. CLINICAL NUTRITION
- Cachexia: prevalence and impact in medicine
- (2008) Benjamin HL Tan et al. CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE
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