TSC but not PTEN loss in starving cones of retinitis pigmentosa mice leads to an autophagy defect and mTORC1 dissociation from the lysosome

Lysosomal recruitment of TSC2 is a universal response to cellular stress

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mTORC1 signaling activates NRF1 to increase cellular proteasome levels

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Loss of mTOR signaling affects cone function, cone structure and expression of cone specific proteins without affecting cone survival

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p62/SQSTM1 functions as a signaling hub and an autophagy adaptor

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Activated mTORC1 promotes long-term cone survival in retinitis pigmentosa mice

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Spatial Control of the TSC Complex Integrates Insulin and Nutrient Regulation of mTORC1 at the Lysosome

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Regulation of TORC1 in Response to Amino Acid Starvation via Lysosomal Recruitment of TSC2

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Neuronal Tsc1/2 complex controls autophagy through AMPK-dependent regulation of ULK1

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Sustained Activation of mTORC1 in Skeletal Muscle Inhibits Constitutive and Starvation-Induced Autophagy and Causes a Severe, Late-Onset Myopathy

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MTORC1 functions as a transcriptional regulator of autophagy by preventing nuclear transport of TFEB

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A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB

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Neuronal autophagy and neurodegenerative diseases

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Autistic-like behaviour and cerebellar dysfunction in Purkinje cell Tsc1 mutant mice

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AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

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Quantifying spatial correlations of fluorescent markers using enhanced background reduction with protein proximity index and correlation coefficient estimations

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Regulable neural progenitor-specific Tsc1 loss yields giant cells with organellar dysfunction in a model of tuberous sclerosis complex

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Ragulator-Rag Complex Targets mTORC1 to the Lysosomal Surface and Is Necessary for Its Activation by Amino Acids

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mTOR: from growth signal integration to cancer, diabetes and ageing

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Tuberous Sclerosis Complex Activity Is Required to Control Neuronal Stress Responses in an mTOR-Dependent Manner

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An Atg1/Atg13 Complex with Multiple Roles in TOR-mediated Autophagy Regulation

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A Role for Ubiquitin in Selective Autophagy

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Skeletal Muscle-Specific Ablation of raptor, but Not of rictor, Causes Metabolic Changes and Results in Muscle Dystrophy

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Stimulation of the insulin/mTOR pathway delays cone death in a mouse model of retinitis pigmentosa

(2008) Claudio Punzo et al.   NATURE NEUROSCIENCE