Nrf2-driven TERT regulates pentose phosphate pathway in glioblastoma

Costunolide induces lung adenocarcinoma cell line A549 cells apoptosis through ROS (reactive oxygen species)-mediated endoplasmic reticulum stress

(2016) Zhen Wang et al.   CELL BIOLOGY INTERNATIONAL

Nrf2 regulates ROS production by mitochondria and NADPH oxidase

(2015) Stjepana Kovac et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Telomerase regulates MYC-driven oncogenesis independent of its reverse transcriptase activity

(2015) Cheryl M. Koh et al.   JOURNAL OF CLINICAL INVESTIGATION

Expression level of hTERT is regulated by somatic mutation and common single nucleotide polymorphism at promoter region in glioblastoma

(2015) Chul-Kee Park et al.   Oncotarget

Non-esterified fatty acids activate the ROS–p38–p53/Nrf2 signaling pathway to induce bovine hepatocyte apoptosis in vitro

(2014) Yuxiang Song et al.   APOPTOSIS

Chaetocin-induced ROS-mediated apoptosis involves ATM–YAP1 axis and JNK-dependent inhibition of glucose metabolism

(2014) D Dixit et al.   Cell Death & Disease

TIGAR Is Required for Efficient Intestinal Regeneration and Tumorigenesis

(2013) Eric C. Cheung et al.   DEVELOPMENTAL CELL

The emerging role of the Nrf2-Keap1 signaling pathway in cancer

(2013) M. C. Jaramillo et al.   GENES & DEVELOPMENT

Transcription factor NRF2 regulates miR-1 and miR-206 to drive tumorigenesis

(2013) Anju Singh et al.   JOURNAL OF CLINICAL INVESTIGATION

Inhibition of nuclear factor-erythroid 2–related factor (Nrf2) by caveolin-1 promotes stress-induced premature senescence

(2013) Daniela Volonte et al.   MOLECULAR BIOLOGY OF THE CELL

TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal

(2013) P. J. Killela et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Frequency of TERT promoter mutations in human cancers

(2013) João Vinagre et al.   Nature Communications

Nrf2 Redirects Glucose and Glutamine into Anabolic Pathways in Metabolic Reprogramming

(2012) Yoichiro Mitsuishi et al.   CANCER CELL

Antitelomerase Therapy Provokes ALT and Mitochondrial Adaptive Mechanisms in Cancer

(2012) Jian Hu et al.   CELL

Glucose Utilization via Glycogen Phosphorylase Sustains Proliferation and Prevents Premature Senescence in Cancer Cells

(2012) Elena Favaro et al.   Cell Metabolism

Linking Glycogen and Senescence in Cancer Cells

(2012) Susana Ros et al.   Cell Metabolism

Glucose-6-phosphate dehydrogenase, NADPH, and cell survival

(2012) Robert C. Stanton   IUBMB LIFE

Cancer metabolism: current perspectives and future directions

(2012) C Muñoz-Pinedo et al.   Cell Death & Disease

Inhibition of Casein kinase-2 induces p53-dependent cell cycle arrest and sensitizes glioblastoma cells to tumor necrosis factor (TNFα)-induced apoptosis through SIRT1 inhibition

(2012) D Dixit et al.   Cell Death & Disease

The efficiency of tumor-specific pH-responsive peptide-modified polymeric micelles containing paclitaxel

(2011) Bing-Xiang Zhao et al.   BIOMATERIALS

Involvement of TNFα-induced TLR4–NF-κB and TLR4–HIF-1α feed-forward loops in the regulation of inflammatory responses in glioma

(2011) Richa Tewari et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Telomere dysfunction induces metabolic and mitochondrial compromise

(2011) Ergün Sahin et al.   NATURE

p53 regulates biosynthesis through direct inactivation of glucose-6-phosphate dehydrogenase

(2011) Peng Jiang et al.   NATURE CELL BIOLOGY

hTERT Overexpression Alleviates Intracellular ROS Production, Improves Mitochondrial Function, and Inhibits ROS-Mediated Apoptosis in Cancer Cells

(2010) I. R. Indran et al.   CANCER RESEARCH

Manumycin inhibits STAT3, telomerase activity, and growth of glioma cells by elevating intracellular reactive oxygen species generation

(2009) Deobrat Dixit et al.   FREE RADICAL BIOLOGY AND MEDICINE

The Nrf2-Antioxidant Response Element Signaling Pathway and Its Activation by Oxidative Stress

(2009) Truyen Nguyen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Telomerase does not counteract telomere shortening but protects mitochondrial function under oxidative stress

(2008) S. Ahmed et al.   JOURNAL OF CELL SCIENCE

Cancer related mutations in NRF2 impair its recognition by Keap1-Cul3 E3 ligase and promote malignancy

(2008) T. Shibata et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA