Review
Polymer Science
Heba A. Gad, Autumn Roberts, Samirah H. Hamzi, Haidy A. Gad, Ilham Touiss, Ahmed E. Altyar, Osama A. Kensara, Mohamed L. Ashour
Summary: Jojoba is a widely used medicinal plant with seeds and oil that have a long history of treating various ailments. The oil has pharmacological applications such as antioxidant, anti-inflammatory, and antimicrobial activities, and is used in pharmaceutical and cosmetic industries. Jojoba oil is highly valued for its composition and has industrial applications like anti-rodent and insecticidal properties.
Review
Medicine, General & Internal
Michael Kaiser, Rama Abdin, Marita Yaghi, Simonetta I. Gaumond, Joaquin J. Jimenez, Naiem T. Issa
Summary: This review provides a comprehensive overview of the causes of beard alopecia in men, including prevalence, pathophysiology, clinical presentation, and treatment. The more common causes highlighted in this review include alopecia areata and pseudofolliculitis barbae, as well as infectious causes such as tinea barbae and herpes simplex folliculitis, and rare causes such as dermatopathia pigmentosa reticularis and frontal fibrosing alopecia. This review is an important resource for clinicians dealing with patients suffering from beard alopecia.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Biochemistry & Molecular Biology
Lydie Carreres, Zuzana Macek Jilkova, Guillaume Vial, Patrice N. Marche, Thomas Decaens, Herve Lerat
Summary: Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease, and research is focusing on decoding the molecular mechanisms behind it to identify new therapeutic targets. Reliable, simple, and reproducible tools are necessary for investigating these pathways, with animal models such as diet-induced NAFLD and NASH being developed to mimic the human disease. Rat models, specifically the dietary model of NAFLD and NASH, are being used to study different dietary compositions and their effects on liver pathogenesis.
Review
Biotechnology & Applied Microbiology
Melania Pilz, Philipp Cavelius, Farah Qoura, Dania Awad, Thomas Brueck
Summary: This comprehensive review introduces a novel class of ribosomally synthesized lipopeptides and commonly occurring non-ribosomal lipopeptides, highlighting their structural features, self-assembly, and associated functions. The common production routes, including genetic engineering strategies, are also discussed. Furthermore, the potential applications of lipopeptides in personal care and cosmetics, as well as the pharmaceutical industry, are detailed, and the safety and sustainable production of lipopeptide formulations are addressed.
BIOTECHNOLOGY ADVANCES
(2023)
Review
Genetics & Heredity
Tais Menezes do Moinho, Sandro Leao Matos, Carla R. O. Carvalho
Summary: Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease in the world and is associated with obesity. Currently, there is no official treatment for NAFLD, but there are synthetic drugs and herbal products being studied for potential treatment.
JOURNAL OF MOLECULAR MEDICINE-JMM
(2022)
Review
Gastroenterology & Hepatology
Alessandra Elvevi, Alice Laffusa, Miki Scaravaglio, Roberta Elisa Rossi, Raffaella Longarini, Anna Maria Stagno, Laura Cristoferi, Antonio Ciaccio, Diego Luigi Cortinovis, Pietro Invernizzi, Sara Massironi
Summary: Cholangiocarcinoma is a heterogeneous group of neoplasms of the bile ducts, with an increasing global incidence. Chronic inflammation of the biliary epithelium and bile stasis are the main risk factors. Liver resection followed by chemotherapy is the preferred treatment option, and targeted therapies and immune checkpoint inhibitors have shown promise as second- or third-line treatments.
ANNALS OF HEPATOLOGY
(2022)
Review
Chemistry, Multidisciplinary
Pedro Farinha, Joao M. P. Coelho, Catarina Pinto Reis, Maria Manuela Gaspar
Summary: Magnetic nanoparticles (MNPs) have been widely studied for diagnostic purposes in medicine, especially in Magnetic Resonance Imaging (MRI). Current research focus is on developing MNPs with better safety profiles and enhanced magnetic properties to overcome challenges in their market entry.
Review
Agricultural Engineering
Tengku Nilam Baizura Tengku Ibrahim, Nur Azalina Suzianti Feisal, Noor Haziqah Kamaludin, Wai Yan Cheah, Vivien How, Amit Bhatnagar, Zengling Ma, Pau Loke Show
Summary: This review summarizes microalgae species capable of producing metabolites and comprehensively discusses the potential applications of these metabolites in the healthcare and pharmaceutical industries. It greatly assists industrial stakeholders, investors, and researchers in making business decisions, investing in ventures, and advancing the production of microalgae-based metabolites.
BIORESOURCE TECHNOLOGY
(2023)
Review
Chemistry, Analytical
Lefteris Benos, Aristotelis C. Tagarakis, Georgios Dolias, Remigio Berruto, Dimitrios Kateris, Dionysis Bochtis
Summary: The study provides a comprehensive review of recent scholarly literature on machine learning in agriculture, highlighting crop management as a central focus and the utilization of various machine learning algorithms including Artificial Neural Networks. By using a variety of sensors to collect reliable input data, the efficiency of data analysis has been significantly improved.
Review
Biochemistry & Molecular Biology
Yasir Qasim Almajidi, Jitendra Gupta, Fatime Satar Sheri, Rahman S. Zabibah, Ahmed Faisal, Akbarali Ruzibayev, Mohaned Adil, Mohamed J. Saadh, Mahmood Jasem Jawad, Fahad Alsaikhan, Asghar Narmani, Bagher Farhood
Summary: In this review, recent achievements and advances associated with chitosan-based hydrogels for drug delivery, regenerative medicine, disease detection, and therapy are summarized.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Review
Pathology
Sulieman Ibraheem Shelash Al-Hawary, Ebraheem Abdu Musad Saleh, Nodirjon Akhmetovich Mamajanov, Nataliya S. Gilmanova, Hashem O. Alsaab, Adel Alghamdi, Shakeel Ahmed Ansari, Ahmed Hussien Radie Alawady, Ali Hashiem Alsaalamy, Ahmed Jaber Ibrahim
Summary: According to the International Agency for Research on Cancer, breast cancer is more common than lung cancer globally. By 2040, mortality from breast cancer will rise by 50% and 40%, respectively. Despite advances in chemotherapy, endocrine therapy, and HER2-targeted therapy, breast cancer metastases and recurrences remain challenging to treat.
PATHOLOGY RESEARCH AND PRACTICE
(2023)
Review
Biochemistry & Molecular Biology
Alessandro Mantovani, Rosa Lombardi, Filippo Cattazzo, Chiara Zusi, Davide Cappelli, Andrea Dalbeni
Summary: Accumulating evidence suggests that NAFLD is independently associated with an increased risk of CKD, and further studies are needed to determine whether the name change to MAFLD improves the accuracy of detecting CKD patients.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Review
Pharmacology & Pharmacy
Aslihan Hilal Algan, Ayca Gungor-Ak, Aysegul Karatas
Summary: Carotenoids are natural lipid-soluble pigments that play important roles in nature and in human health. Lutein, a member of the carotenoid family, is crucial for central vision and photoprotection in the eye. Nanoscale delivery systems are being explored to enhance the stability and bioavailability of lutein for targeted delivery.
Review
Biochemistry & Molecular Biology
Pravat Ranjan Guru, Rajat Kumar Kar, Amit Kumar Nayak, Snehamayee Mohapatra
Summary: Biopolysaccharides extracted from plants have gained significant attention as pharmaceutical excipients in various dosage forms due to their wide availability, sustainable production, easy extraction methods, aqueous solubility, swelling capability, non-toxicity, and biodegradability. This comprehensive review highlights the extensive use of plant-derived biopolysaccharides as effective pharmaceutical excipients in the formulation of different dosage forms such as gels, pastes, films, emulsions, suspensions, capsules, tablets, nanoparticles, microparticles, beads, buccal formulations, transdermal formulations, ocular formulations, nasal formulations, etc.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Review
Chemistry, Medicinal
Yusuf A. Haggag, Abeer A. Abd Elrahman, Roland Ulber, Ahmed Zayed
Summary: Fucoidan is a versatile group of polysaccharides derived from marine organisms, such as brown algae and marine invertebrates. It has attracted significant attention in the pharmaceutical industry due to its diverse physicochemical properties and potential bioactivities. Fucoidan possesses negatively charged surfaces, low/high molecular weight, and water solubility, and it has shown promising effects in various biomedical applications, including anti-tumor, immunomodulatory, and antiviral activities. The current research focuses on formulating fucoidan in different pharmaceutical dosage forms to effectively deliver its therapeutic benefits and enhance drug delivery systems. This study highlights the importance of further clinical research and market availability of fucoidan formulations.