Article
Biochemistry & Molecular Biology
Chen Zhang, Xinling Song, Weijun Cui, Qihang Yang
Summary: The study found that PERP extracted from Pleurotus eryngii residues may serve as a potential anti-aging agent, positively impacting the brain, liver, kidneys, and skin. This polysaccharide, comprised of multiple monosaccharides, with a moderate molecular weight and spherical structure, showed promising effects in animal experiments.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Biochemistry & Molecular Biology
Tania Petraglia, Tiziana Latronico, Angela Fanigliulo, Aniello Crescenzi, Grazia Maria Liuzzi, Rocco Rossano
Summary: This study evaluated the antioxidant and neuroprotective activity of an enriched polysaccharide fraction (EPF) obtained from the fruiting body of cultivated P. eryngii. The EPF showed high content of (1-3; 1-6)-beta-D-glucans and exhibited significant scavenging activities against DPPH, superoxide, hydroxyl, and nitric oxide radicals. It also demonstrated biocompatibility and reduced oxidative stress in DI-TNC1 cells. These findings suggest that polysaccharides extracted from P. eryngii could be used as functional food to enhance antioxidant defenses.
Article
Biochemistry & Molecular Biology
Lei Chen, Ai Ren, Yushi Wang, Yunhe Qu, Hesong Gong, Kevin H. Mayo, Yifa Zhou, Hairong Cheng
Summary: This study demonstrates that WPEP-N-b, a heterogalactan from Pleurotus eryngii, enhances immunity in immunosuppressed mice. WPEP-N-b improves immune organ index, peripheral blood immune cell content, splenocyte proliferation, NK cell activity, and T lymphocyte subpopulations. Additionally, WPEP-N-b restores cytokine levels and macrophage activity, and its mechanisms involve Toll-like receptor and signaling pathways.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Chemistry, Applied
Hellen Abreu, Matheus Zavadinack, Fhernanda R. Smiderle, Thales R. Cipriani, Lucimara M. C. Cordeiro, Marcello Iacomini
Summary: Polysaccharides from P. eryngii mushroom were extracted using low-cost technologies, resulting in different fractions with immunostimulatory properties on THP-1 macrophages. The main polysaccharides included Mannogalactan and various β-glucans, which were not cytotoxic and induced different cellular responses. This simple technique allows the obtainment of fractions with distinct immunomodulatory activities, showing the potential for future biological effects research.
CARBOHYDRATE POLYMERS
(2021)
Article
Biochemistry & Molecular Biology
Pin Gong, Hui Long, Yuxi Guo, Siyuan Wang, Fuxin Chen, Xuefeng Chen
Summary: This study focused on the chemical characterization and biological activities of Pleurotus eryngii polysaccharides (PEPs). The two fractions, WPS and P-1, exhibited different chemical structures and molecular weights, and showed antioxidant and hypoglycemic activities.
Article
Biochemistry & Molecular Biology
Meihong Cai, Gang Zhang, Changzhu Li, Xiaochen Chen, Haiying Cui, Lin Lin
Summary: This study introduced pomegranate peel polyphenols embedded in chitosan to prepare antibacterial nanofibers, showing effective inhibition of bacterial growth on food surfaces (e.g. E. coli) without affecting food quality. By adding different concentrations of polyphenols and polysaccharides, the properties of nanofibers can be controlled to enhance encapsulation rate and tensile strength.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Nutrition & Dietetics
Yuanyuan Zhao, Zhen Zhang, Li Wang, Wen Li, Jianming Du, Shengxiang Zhang, Xuefeng Chen
Summary: In this study, the structure of Pleurotus eryngii polysaccharides (PEPs) was characterized, and the mechanism of PEP on obesity and hyperlipidemia induced by high-fat diet was evaluated by metabonomic analysis. The results showed that PEPs could significantly reduce blood lipids and prevent and treat obesity and hyperlipidemia caused by a high-fat diet by regulating amino acid metabolism, fatty acid metabolism, and metabolic pathways such as the citric cycle (TCA cycle). Therefore, PEPs may be used as a functional food adjuvant for the prevention and treatment of high-fat diet-induced obesity and hyperlipidemia.
FRONTIERS IN NUTRITION
(2023)
Article
Pharmacology & Pharmacy
Stamatia-Angeliki Kleftaki, Stamatia Simati, Charalampia Amerikanou, Aristea Gioxari, Chara Tzavara, Georgios Zervakis, Nick Kalogeropoulos, Alexander Kokkinos, Andriana C. Kaliora
Summary: The study found that Pleurotus eryngii can improve postprandial blood sugar levels and appetite sensations in obese individuals, while also regulating ghrelin levels. This effect may be attributed to the bioactive polysaccharides in Pleurotus eryngii, which inhibit the activity of enzymes catalyzing carbohydrate hydrolysis, causing delayed gastric emptying and glucose absorption.
PHARMACOLOGICAL RESEARCH
(2022)
Article
Chemistry, Applied
Nicola Landi, Maja Grundner, Sara Ragucci, Miha Pavsic, Martina Mravinec, Paolo Pedone, Kristina Sepcic, Antimo Di Maro
Summary: This study reports the characterization and cytotoxic effects of four novel ribotoxin-like proteins (RL-Ps), called eryngitins, found in the king oyster mushroom. These proteins show enzymatic activity and exhibit cytotoxic action against insect cells, suggesting their potential use as bioinsecticides in biotechnological applications.
Article
Food Science & Technology
Sai Ma, Xinyi Li, Qi Tao, Qiuhui Hu, Wenjian Yang, Benard Muinde Kimatu, Gaoxing Ma
Summary: Pleurotus eryngii polysaccharides and their digestion products show significant interactions with intestinal mucus, which can be influenced by digestion process and potentially impact the activity and immune activity of the polysaccharides, as well as the transport of other nutrients.
FOOD SCIENCE & NUTRITION
(2023)
Article
Biochemistry & Molecular Biology
Jan Stastny, Petr Marsik, Jan Tauchen, Matej Bozik, Anna Mascellani, Jaroslav Havlik, Premysl Landa, Ivan Jablonsky, Jakub Treml, Petra Herczogova, Roman Bleha, Andriy Synytsya, Pavel Kloucek
Summary: Edible medicinal mushrooms within the higher fungi group have a long history of being used for food and folk medicine. The Pleurotus genus, represented by Pleurotus ostreatus, has been widely cultivated and studied. In this study, lesser-known Pleurotus species were examined for their antioxidant and anti-inflammatory activities. Significant differences were found among the extracts, with P. flabellatus showing strong radical scavenging activity and P. ostreatus Florida demonstrating potent NF-kappa B inhibition. These findings suggest the therapeutic potential of these mushrooms for further investigation and clinical trials.
Article
Biochemistry & Molecular Biology
Guangming Chen, Nan Jiang, Junping Zheng, Haiming Hu, Huabing Yang, Aizhen Lin, Baifei Hu, Hongtao Liu
Summary: In this study, two homogeneous polysaccharides (APS-A1 and APS-B1) were isolated from Astragalus membranaceus and their chemical structures were characterized. APS-A1 had a 1,4-alpha-D-Glcp backbone with a 1,4,6-alpha-D-Glcp branch every ten residues, while APS-B1 was a heteropolysaccharide composed of glucose, galactose, and arabinose. Bioactivity assays showed that both APS-A1 and APS-B1 exhibited potential anti-inflammatory activity.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Food Science & Technology
Shuang Lv, Xiaolin Zhu, Zhenbin Liu, Liangbin Hu, Dan Xu, Bimal Chitrakar, Haizhen Mo, Hongbo Li
Summary: This study evaluated the feasibility of preparing papery food using Pleurotus eryngii as a raw material through the papermaking process. The results showed that PSP and PMP were more popular among consumers in terms of formability, mouth feel, and overall palatability, with PSP also exhibiting better moisture resistance and thermal decomposition performance.
Article
Chemistry, Applied
Bingyi Wang, Ning Zhao, Jun Li, Ruoyun Xu, Tieru Wang, Li Guo, Man Ma, Mingtao Fan, Xinyuan Wei
Summary: The study found that the addition of selenium using enriched Lactobacillus plantarum can significantly enhance antioxidant activity and flavor properties of fermented Pleurotus eryngii. This method had a positive effect on total phenolic content and DPPH radical scavenging activity. Additionally, the enriched Lactobacillus plantarum also led to an increased lactic acid to acetic acid ratio and enhanced umami intensity in the fermented product.
Article
Multidisciplinary Sciences
Xiaoyun Huang, Liuting Zhou, Xiaofeng You, Haidong Han, Xinzhu Chen, Xiusheng Huang
Summary: This study aimed to investigate the effect of fermented spent mushroom substrate from Pleurotus eryngii (SMPE) supplementation on production performance, meat quality and rumen bacterial community structure of Hu sheep. The results showed that the addition of fermented SMPE can significantly improve the production performance, meat quality and rumen bacterial community diversity and abundance of Hu sheep.
SCIENTIFIC REPORTS
(2023)
