期刊
FRONTIERS IN CELLULAR NEUROSCIENCE
卷 10, 期 -, 页码 -出版社
FRONTIERS MEDIA SA
DOI: 10.3389/fncel.2016.00092
关键词
closed-loop; EEG; TMS; non-invasive brain stimulation; NIBS
资金
- Fortune Junior Intramural research funding program at the Faculty of Medicine in Tubingen (IZKF)
- Inter-University Center for Medical Technologies Stuttgart-Tilbingen (IZST) Industry-on-Campus Project [211]
- Open Access Publishing Fund of University of Tubingen
Closed-loop neuroscience is receiving increasing attention with recent technological advances that enable complex feedback loops to be implemented with millisecond resolution on commodity hardware. We summarize emerging conceptual and methodological frameworks that are available to experimenters investigating a brain in the loop using non-invasive brain stimulation and briefly review the experimental and therapeutic implications. We take the view that closed-loop neuroscience in fact deals with two conceptually quite different loops: a 'brain-state dynamics loop, used to couple with and modulate the trajectory of neuronal activity patterns, and a task dynamics loop, that is the bidirectional motor-sensory interaction between brain and (simulated) environment, and which enables goal-directed behavioral tasks to be incorporated. Both loops need to be considered and combined to realize the full experimental and therapeutic potential of closed-loop neuroscience.
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