RELN Mutations in Autism Spectrum Disorder

Association and gene-gene interactions study of reelin signaling pathway related genes with autism in the Han Chinese population

(2015) Yidong Shen et al.   Autism Research

Reelin supplementation recovers synaptic plasticity and cognitive deficits in a mouse model for Angelman syndrome

(2015) Whitney R. Hethorn et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Whole-genome sequencing of quartet families with autism spectrum disorder

(2015) Ryan K C Yuen et al.   NATURE MEDICINE

Gene Mutation Analysis in 253 Chinese Children with Unexplained Epilepsy and Intellectual/Developmental Disabilities

(2015) Yujia Zhang et al.   PLoS One

Impaired Reelin-Dab1 Signaling Contributes to Neuronal Migration Deficits of Tuberous Sclerosis Complex

(2015) Uk Yeol Moon et al.   Cell Reports

Autism spectrum disorders and neuropathology of the cerebellum

(2015) David R. Hampson et al.   Frontiers in Neuroscience

Cerebellar gray matter and lobular volumes correlate with core autism symptoms

(2015) Anila M. D'Mello et al.   NeuroImage-Clinical

Reelin gene variants and risk of autism spectrum disorders: An integrated meta-analysis

(2014) Zhenling Wang et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Single and combined effects of prenatal immune activation and peripubertal stress on parvalbumin and reelin expression in the hippocampal formation

(2014) Sandra Giovanoli et al.   BRAIN BEHAVIOR AND IMMUNITY

Reelin Induces Erk1/2 Signaling in Cortical Neurons Through a Non-canonical Pathway

(2014) Gum Hwa Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Synaptic, transcriptional and chromatin genes disrupted in autism

(2014) Silvia De Rubeis et al.   NATURE

The contribution of de novo coding mutations to autism spectrum disorder

(2014) Ivan Iossifov et al.   NATURE

A framework for the interpretation of de novo mutation in human disease

(2014) Kaitlin E Samocha et al.   NATURE GENETICS

The Cerebellum, Sensitive Periods, and Autism

(2014) Samuel S.-H. Wang et al.   NEURON

How does Reelin control neuronal migration and layer formation in the developing mammalian neocortex?

(2014) Katsutoshi Sekine et al.   NEUROSCIENCE RESEARCH

Regional Alterations in Purkinje Cell Density in Patients with Autism

(2014) Jerry Skefos et al.   PLoS One

Increased binding of MeCP2 to the GAD1 and RELN promoters may be mediated by an enrichment of 5-hmC in autism spectrum disorder (ASD) cerebellum

(2014) A Zhubi et al.   Translational Psychiatry

Autism genetics

(2013) Antonio M. Persico et al.   BEHAVIOURAL BRAIN RESEARCH

Activity-dependent neuronal signalling and autism spectrum disorder

(2013) Daniel H. Ebert et al.   NATURE

Interpreting the role of de novo protein-coding mutations in neuropsychiatric disease

(2013) Jacob Gratten et al.   NATURE GENETICS

Reelin Mobilizes a VAMP7-Dependent Synaptic Vesicle Pool and Selectively Augments Spontaneous Neurotransmission

(2013) Manjot Bal et al.   NEURON

The Cerebellum and Cognitive Function: 25 Years of Insight from Anatomy and Neuroimaging

(2013) Randy L. Buckner   NEURON

Performance Comparison of Bench-Top Next Generation Sequencers Using Microdroplet PCR-Based Enrichment for Targeted Sequencing in Patients with Autism Spectrum Disorder

(2013) Eriko Koshimizu et al.   PLoS One

Association study between genes in Reelin signaling pathway and autism identifies DAB1 as a susceptibility gene in a Chinese Han population

(2013) Jun Li et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Multiple Autism-Linked Genes Mediate Synapse Elimination via Proteasomal Degradation of a Synaptic Scaffold PSD-95

(2012) Nien-Pei Tsai et al.   CELL

Consensus Paper: Pathological Role of the Cerebellum in Autism

(2012) S. Hossein Fatemi et al.   CEREBELLUM

Reelin supplementation recovers sensorimotor gating, synaptic plasticity and associative learning deficits in the heterozygous reeler mouse

(2012) Justin T Rogers et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Autistic-like behaviour and cerebellar dysfunction in Purkinje cell Tsc1 mutant mice

(2012) Peter T. Tsai et al.   NATURE

Patterns and rates of exonic de novo mutations in autism spectrum disorders

(2012) Benjamin M. Neale et al.   NATURE

De novo mutations revealed by whole-exome sequencing are strongly associated with autism

(2012) Stephan J. Sanders et al.   NATURE

Rate of de novo mutations and the importance of father’s age to disease risk

(2012) Augustine Kong et al.   NATURE

Vldlr overexpression causes hyperactivity in rats

(2012) Keiko Iwata et al.   Molecular Autism

Autism spectrum disorders—A genetics review

(2011) Judith H Miles   GENETICS IN MEDICINE

Reelin supplementation enhances cognitive ability, synaptic plasticity, and dendritic spine density

(2011) J. T. Rogers et al.   LEARNING & MEMORY

Rare De Novo Variants Associated with Autism Implicate a Large Functional Network of Genes Involved in Formation and Function of Synapses

(2011) Sarah R. Gilman et al.   NEURON

Reelin deficiency causes specific defects in the molecular composition of the synapses in the adult brain

(2011) A. Ventruti et al.   NEUROSCIENCE

Postsynaptic ProSAP/Shank scaffolds in the cross-hair of synaptopathies

(2011) Andreas M. Grabrucker et al.   TRENDS IN CELL BIOLOGY

mTOR: A pathogenic signaling pathway in developmental brain malformations

(2011) Peter B. Crino   TRENDS IN MOLECULAR MEDICINE

Behavioural phenotyping assays for mouse models of autism

(2010) Jill L. Silverman et al.   NATURE REVIEWS NEUROSCIENCE

A structural role for arginine in proteins: Multiple hydrogen bonds to backbone carbonyl oxygens

(2010) C.L. Borders et al.   PROTEIN SCIENCE

Perseverative responding and neuroanatomical alterations in adult heterozygous reeler mice are mitigated by neonatal estrogen administration

(2010) Simone Macrì et al.   PSYCHONEUROENDOCRINOLOGY

Structural Basis for Specific Recognition of Reelin by Its Receptors

(2010) Norihisa Yasui et al.   STRUCTURE

Interactions between neuroactive steroids and reelin haploinsufficiency in Purkinje cell survival

(2009) Filippo Biamonte et al.   NEUROBIOLOGY OF DISEASE

Glutamatergic cerebellar granule neurons synthesize and secrete reelin in vitro

(2009) Mélanie Sinagra et al.   Neuron Glia Biology

Reelin Secreted by GABAergic Neurons Regulates Glutamate Receptor Homeostasis

(2009) Cecilia Gonzalez Campo et al.   PLoS One