期刊
JOURNAL OF GERIATRIC ONCOLOGY
卷 7, 期 4, 页码 249-257出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.jgo.2015.12.002
关键词
Comorbidity; Multimorbidity; Cancer; Geriatric oncology; Aged
资金
- NCATS NIH HHS [UL1 TR001863] Funding Source: Medline
- NCI NIH HHS [R01 CA177592, R25 CA102618, UG1 CA189961, K12 CA120780] Funding Source: Medline
- NIA NIH HHS [U13 AG038151, R03 AG042342] Funding Source: Medline
Comorbidity is an issue of growing importance due to changing demographics and the increasing number of adults over the age of 65 with cancer. The best approach to the clinical management and decision-making in older adults with comorbid conditions remains unclear. In May 2015, the Cancer and Aging Research Group, in collaboration with the National Cancer Institute and the National Institute on Aging, met to discuss the design and implementation of intervention studies in older adults with cancer. A presentation and discussion on comorbidity measurement, interventions, and future research was included. In this article, we discuss the relevance of comorbidities in cancer, examine the commonly used tools to measure comorbidity, and discuss the future direction of comorbidity research. Incorporating standardized comorbidity measurement, relaxing clinical trial eligibility criteria, and utilizing novel trial designs are critical to developing a larger and more generalizable evidence base to guide the management of these patients. Creating or adapting comorbidity management strategies for use in older adults with cancer is necessary to define optimal care for this growing population. (C) 2015 Elsevier Ltd. All rights reserved.
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