Accelerating chemoselective peptide bond formation using bis(2-selenylethyl)amido peptide selenoester surrogates

A straightforward method for automated Fmoc-based synthesis of bio-inspired peptide crypto-thioesters

(2016) Victor P. Terrier et al.   Chemical Science

An efficient computational model to predict protonation at the amide nitrogen and reactivity along the C–N rotational pathway

(2015) Roman Szostak et al.   CHEMICAL COMMUNICATIONS

Rapid Additive-Free Selenocystine–Selenoester Peptide Ligation

(2015) Nicholas J. Mitchell et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

One-pot chemical synthesis of small ubiquitin-like modifier protein–peptide conjugates using bis(2-sulfanylethyl)amido peptide latent thioester surrogates

(2015) Emmanuelle Boll et al.   Nature Protocols

Synthesis of Unprotected Linear or Cyclic O-Acyl Isopeptides in Water Using Bis(2-sulfanylethyl)amido Peptide Ligation

(2015) Rémi Desmet et al.   ORGANIC LETTERS

Selectively Activatable Latent Thiol and Selenolesters Simplify the Access to Cyclic or Branched Peptide Scaffolds

(2015) Laurent Raibaut et al.   ORGANIC LETTERS

Insights into the deselenization of selenocysteine into alanine and serine

(2015) Shahar Dery et al.   Chemical Science

Semi-synthesis of a HGF/SF kringle one (K1) domain scaffold generates a potent in vivo MET receptor agonist

(2015) Claire Simonneau et al.   Chemical Science

From protein total synthesis to peptide transamidation and metathesis: playing with the reversibility of N,S-acyl or N,Se-acyl migration reactions

(2014) Oleg Melnyk et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Selenopeptide Transamidation and Metathesis

(2014) Nathalie Ollivier et al.   ORGANIC LETTERS

Access to Large Cyclic Peptides by a One-Pot Two-Peptide Segment Ligation/Cyclization Process

(2014) Emmanuelle Boll et al.   ORGANIC LETTERS

A novel PEG-based solid support enables the synthesis of >50 amino-acid peptide thioesters and the total synthesis of a functional SUMO-1 peptide conjugate

(2014) Emmanuelle Boll et al.   Chemical Science

Development of New Thioester Equivalents for Protein Chemical Synthesis

(2013) Ji-Shen Zheng et al.   ACCOUNTS OF CHEMICAL RESEARCH

Total synthesis of biotinylated N domain of human hepatocyte growth factor

(2013) Laurent Raibaut et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Solid phase synthesis of peptide-selenoesters

(2013) Artin Ghassemian et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Examination of native chemical ligation using peptidyl prolyl thioesters

(2013) Takahiro Nakamura et al.   CHEMICAL COMMUNICATIONS

Chemical assembly of N-glycoproteins: a refined toolbox to address a ubiquitous posttranslational modification

(2013) Carlo Unverzagt et al.   CHEMICAL SOCIETY REVIEWS

Tidbits for the synthesis ofbis(2-sulfanylethyl)amido (SEA) polystyrene resin, SEA peptides and peptide thioesters

(2013) Nathalie Ollivier et al.   JOURNAL OF PEPTIDE SCIENCE

A Thioethylalkylamido (TEA) Thioester Surrogate in the Synthesis of a Cyclic Peptide via a Tandem Acyl Shift

(2013) Misako Taichi et al.   ORGANIC LETTERS

Bis(2-sulfanylethyl)amido Peptides Enable Native Chemical Ligation at Proline and Minimize Deletion Side-Product Formation

(2013) Laurent Raibaut et al.   ORGANIC LETTERS

Protein chemical synthesis by serine and threonine ligation

(2013) Y. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Insitu thioester formation for protein ligation using α-methylcysteine

(2013) Fabienne Burlina et al.   Chemical Science

Access to Cyclic or Branched Peptides Using Bis(2-sulfanylethyl)amido Side-Chain Derivatives of Asp and Glu

(2012) Emmanuelle Boll et al.   ORGANIC LETTERS

Shedding-Generated Met Receptor Fragments can be Routed to Either the Proteasomal or the Lysosomal Degradation Pathway

(2012) Frédéric Ancot et al.   TRAFFIC

Total Chemical Synthesis of a 304 Amino Acid K48-Linked Tetraubiquitin Protein

(2011) K. S. Ajish Kumar et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Design, Total Chemical Synthesis, and X-Ray Structure of a Protein Having a Novel Linear-Loop Polypeptide Chain Topology

(2011) Kalyaneswar Mandal et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A One-Pot Three-Segment Ligation Strategy for Protein Chemical Synthesis

(2011) Nathalie Ollivier et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Preformed Selenoesters Enable Rapid Native Chemical Ligation at Intractable Sites

(2011) Thomas Durek et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

N-Sulfanylethylanilide Peptide as a Crypto-Thioester Peptide

(2011) Kohei Sato et al.   CHEMBIOCHEM

Synthesis of Peptide Alkylthioesters Using the IntramolecularN,S-Acyl Shift Properties of Bis(2-sulfanylethyl)amido Peptides

(2011) Julien Dheur et al.   JOURNAL OF ORGANIC CHEMISTRY

Rethinking amide bond synthesis

(2011) Vijaya R. Pattabiraman et al.   NATURE

Histone H2B ubiquitylation disrupts local and higher-order chromatin compaction

(2011) Beat Fierz et al.   Nature Chemical Biology

Synthesis of Thiazolidine Thioester Peptides and Acceleration of Native Chemical Ligation

(2011) Julien Dheur et al.   ORGANIC LETTERS

Dual Kinetically Controlled Native Chemical Ligation Using a Combination of Sulfanylproline and Sulfanylethylanilide Peptide

(2011) Hao Ding et al.   ORGANIC LETTERS

N-to-C Sequential Ligation Using Peptidyl N,N-Bis(2-mercaptoethyl)amide Building Blocks

(2011) Renliang Yang et al.   ORGANIC LETTERS

Total Chemical Synthesis of Di-ubiquitin Chains

(2010) K. S. Ajish Kumar et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Traceless Ligation of Cysteine Peptides Using Selective Deselenization

(2010) Norman Metanis et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

9-Fluorenylmethoxycarbonyl-Based Solid-Phase Synthesis of Peptide α-Thioesters

(2010) Franziska Mende et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Invited reviewnative chemical ligation applied to the synthesis and bioengineering of circular peptides and proteins

(2010) Richard J. Clark et al.   BIOPOLYMERS

Chemical Protein Synthesis by Kinetically Controlled Ligation of Peptide O-Esters

(2010) Ji-Shen Zheng et al.   CHEMBIOCHEM

Bis(2-sulfanylethyl)amino Native Peptide Ligation

(2010) Nathalie Ollivier et al.   ORGANIC LETTERS

PeptidylN,N-Bis(2-mercaptoethyl)-amides as Thioester Precursors for Native Chemical Ligation†

(2010) Wen Hou et al.   ORGANIC LETTERS

Protein Autoproteolysis: Conformational Strain Linked to the Rate of Peptide Cleavage by the pH Dependence of the N → O Acyl Shift Reaction

(2009) Denny G. A. Johansson et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

N→SAcyl-Transfer-Mediated Synthesis of Peptide Thioesters Using Anilide Derivatives

(2009) Shugo Tsuda et al.   ORGANIC LETTERS

3-Mercaptopropionic acid-mediated synthesis of peptide and protein thioesters

(2008) Jaskiranjit Kang et al.   CHEMICAL COMMUNICATIONS

Total chemical synthesis of proteins

(2008) Stephen B. H. Kent   CHEMICAL SOCIETY REVIEWS